Gene Information

Name : glnA (KPN_04178)
Accession : YP_001337824.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : -
Position : 4577914 - 4579299 bp
Length : 1386 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGCTGAACGAGCACGAAGTGAAGTTTGTCGATCTGCGCTTCACCGATACCAAAGGTAAAGAACAGCACGTCACGATTCC
GTCTCATCAGGTAAATGCCGAATTCTTCGAAGAAGGCAAAATGTTTGATGGCTCCTCGATTGGTGGCTGGAAAGGTATCA
ACGAATCTGACATGGTCCTGATGCCGGACGCGTCCACCGCGGTCATTGACCCGTTCTACGAAGAACCGACCCTGATCATC
CGCTGCGATATCCTCGAGCCAGGCACCCTGCAGGGCTATGACCGTGACCCGCGCTCCATCGCGAAACGCGCTGAAGAGTA
CCTGCGCGCCACCGGCATCGCTGATACCGTCCTGTTCGGGCCAGAACCAGAATTCTTCCTGTTCGACGACATCCGTTTTG
GCGCCTCTATCTCGGGCTCCCATGTCGCGATCGATGACATTGAAGGTGCGTGGAACTCCTCCACCAAATACGAAGGCGGT
AACAAAGGTCACCGTCCGGGCGTGAAAGGGGGTTACTTCCCGGTTCCGCCAGTAGACTCTTCTCAGGACATCCGTTCCAC
CATGTGTATGATCATGGAAGAGATGGGTCTGGTTGTTGAAGCCCATCACCATGAAGTAGCAACCGCAGGTCAGAACGAAG
TGGCAACCCGCTTCAATACCATGACCAAAAAAGCGGATGAAATTCAGATTTACAAATACGTTGTTCACAACGTCGCTCAC
CGCTTTGGTAAAACCGCGACCTTTATGCCGAAACCGATGTTCGGCGACAACGGCTCCGGCATGCACTGCCATATGTCTCT
GGCGAAAAACGGTACCAACCTGTTCTCCGGCGACAAATACGCCGGTCTGTCTGAGCAGGCGCTGTTCTACATCGGCGGCG
TAATCAAACACGCTAAAGCCATCAACGCCCTGGCGAACCCGACCACCAACTCCTACAAGCGTCTGGTCCCGGGTTACGAA
GCGCCGGTTATGCTGGCTTACTCTGCCCGTAACCGCTCTGCCTCTATCCGTATTCCGGTGGTGACCTCTCCGAAAGCGCG
TCGTATCGAAGTGCGCTTCCCGGACCCGGCTGCCAACCCGTACCTGTGCTTTGCGGCGCTGCTGATGGCTGGCCTTGATG
GTATCAAGAACAAAATCCATCCGGGCGAAGCAATGGATAAAAACCTGTATGACCTGCCGCCGGAAGAAGCGAAAGAGATC
CCGCAGGTTGCCGGTTCTCTGGAAGAAGCCCTGCAGGCCCTGGATGCTGACCGCGAGTTCCTGACCGCTGGCGGCGTGTT
CACCAATGACGCTATCGATGCCTACATCGCCCTGCGTATGGAAGAGAACGACCGCGTACGCATGACTCCGCATCCGGTTG
AGTTCGAACTGTACTACAGCGTCTAA

Protein sequence :
MLNEHEVKFVDLRFTDTKGKEQHVTIPSHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFYEEPTLII
RCDILEPGTLQGYDRDPRSIAKRAEEYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGG
NKGHRPGVKGGYFPVPPVDSSQDIRSTMCMIMEEMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAH
RFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALFYIGGVIKHAKAINALANPTTNSYKRLVPGYE
APVMLAYSARNRSASIRIPVVTSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEI
PQVAGSLEEALQALDADREFLTAGGVFTNDAIDAYIALRMEENDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 1e-102 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_001337824.1 glutamine synthetase VFG1399 Protein 3e-114 52