Gene Information

Name : nanE (KPN_03626)
Accession : YP_001337286.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine-6-phosphate 2-epimerase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3010
EC number : -
Position : 3987028 - 3987732 bp
Length : 705 bp
Strand : -
Note : Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate

DNA sequence :
ATGTCTTTACTCGCACAACTGGACCAGCGTATCCGTCATCATGGCGGATTAATTGTCTCCTGCCAGCCGGTGCCGGGCAG
TCCGCTGGATAATCCCGCTATCGTCGCAGCAATGGCGCTGGCGGCTGAGCAGGCGGGAGCGGTAGCGCTGCGCATCGAAG
GCCTGGCCAACCTGCAGGCCGTTCGTCCGTTAGTGACAGTGCCCGTTATTGGGTTGATCAAACGCGATTTGCCCGATAGC
CCGGTGCGTATTACGCCATGGCTGGAAGATATCGACGCGCTGGCGCAGGGCGGAGCGGATATTATTGCTATTGACGGCAC
CCAGCGTCAGCGTCCGGCGTCAGTGTCGGCGCTATTAGCAGAAATTCATCAGCTGGGAAAAGTGGCGATGGCCGATTGCT
CATCTCTCGACGATGCTCTCGAGTGCTGGCAGTTGGGGGCTGAGATTGTCGGGACGACTCTCTCCGGCTATACCGCAGAG
GAGACGCCGGATGAGCCGGATCTGGCGCTGGTGCAATGCCTGAGCGTTGCGGGCTGCAGAGTGATTGCCGAAGGGCGCTA
TAACACGCCTGCCCAGGCGGCGGAGGCGATGCGTTGCGGCGCGTGGGCGGTGACCGTCGGCTCGGCGATTACCCGCCTGG
AGCATATCTGCGGCTGGTATAATACGGCGCTGAAAGCGGCGGTTTGCCCGGCGAATGAGCAATAA

Protein sequence :
MSLLAQLDQRIRHHGGLIVSCQPVPGSPLDNPAIVAAMALAAEQAGAVALRIEGLANLQAVRPLVTVPVIGLIKRDLPDS
PVRITPWLEDIDALAQGGADIIAIDGTQRQRPASVSALLAEIHQLGKVAMADCSSLDDALECWQLGAEIVGTTLSGYTAE
ETPDEPDLALVQCLSVAGCRVIAEGRYNTPAQAAEAMRCGAWAVTVGSAITRLEHICGWYNTALKAAVCPANEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1781 NP_231416.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 1e-41 55
nanE ACA01846.1 N-acetylmannosamine-6-phosphate epimerase Not tested VPI-2 Protein 1e-41 55
VC0395_A1378 YP_001217321.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 2e-41 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanE YP_001337286.1 N-acetylmannosamine-6-phosphate 2-epimerase VFG1114 Protein 5e-42 55