Gene Information

Name : metB (KPN_03410)
Accession : YP_001337036.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Resistance
Product : putative cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 3735312 - 3736460 bp
Length : 1149 bp
Strand : +
Note : -

DNA sequence :
ATGTCATCTATCCACACCCTGAGTGTACATAGCGGAACCTTCACCGACAGCCACGGCGCAGTGATGCCGCCGATTTATGC
CACCTCCACTTTTGCTCAGCCAGCGCCGGGGCAGCATACCGGTTATGAATATTCCCGCAGCGGGAATCCCACCCGCCACG
CGCTGGAGACGGCGATCGCCGACCTGGAAAACGGCACGCGCGGCTACGCGTTCGCCTCCGGGCTGGCCGCCATCTCCACC
GTGCTGGAGCTGCTGGATAAGGACAGTCACCTGGTGGCGGTCGATGATGTGTATGGCGGCACTTACCGCCTGCTGGAAAA
CGTTCGCCGCCGTAGCGCGGGTCTGCAGGTGAGCTGGGTGAAACCCGACGACCTGGCGGGAATTGAAGCGGCGATCCGCC
CCGACACCCGCATGATCTGGGTGGAAACGCCCACCAACCCGCTGCTGAAGCTCGCGGATCTCAGCGCCATCGCCGCCATC
GCGCGCCGCCATAACCTGATCAGCGTCGCCGATAACACCTTCGCTTCGCCGGCGATCCATCGCCCGCTGGAGCATGAGTT
TGATATTGTGGTGCACTCCGCGACCAAGTACCTCAACGGCCATTCCGATGTCGTCGCCGGCCTGGCGGTGGTTGGCGATA
ACTCCGAGCTCGCGGAAAAGCTTGGCTATCTGCAGAATGCGGTAGGCGGCGTGCTTGACCCGTTCAGCAGCTTCCTGACG
CTGCGCGGCATCCGTACCCTGGCGCTGCGGATGGAGCGCCACAGCGCGAACGCGCTGCAGCTCGCCGAATGGCTGGAACA
GCAGCCGGAAGTGGAGCGAGTCTGGTTTCCCTGGCTGGCCTCGCACCCGCATCATCAGCTGGCGCGCCAGCAAATGGCCC
TGCCCGGCGGCATGATTTCGGTGGTGGTGAAGGGCGATGAAGGTTACGCCGAGCGCATCATCAGCAAGCTGCGCTGGTTT
ACGCTTGCGGAGAGCCTGGGCGGCGTGGAGAGTCTGGTGAGCCAGCCCTTCAGCATGACCCATGCCTCGATTCCGCTGGA
GAAACGCCTGGCGAACGGTATCACACCGCAGCTGATCCGCCTGTCGGTGGGGATCGAAGATCCTCACGATCTGATTGCCG
ACTGGCAGCAGGCGCTGCGGAGGGAGTGA

Protein sequence :
MSSIHTLSVHSGTFTDSHGAVMPPIYATSTFAQPAPGQHTGYEYSRSGNPTRHALETAIADLENGTRGYAFASGLAAIST
VLELLDKDSHLVAVDDVYGGTYRLLENVRRRSAGLQVSWVKPDDLAGIEAAIRPDTRMIWVETPTNPLLKLADLSAIAAI
ARRHNLISVADNTFASPAIHRPLEHEFDIVVHSATKYLNGHSDVVAGLAVVGDNSELAEKLGYLQNAVGGVLDPFSSFLT
LRGIRTLALRMERHSANALQLAEWLEQQPEVERVWFPWLASHPHHQLARQQMALPGGMISVVVKGDEGYAERIISKLRWF
TLAESLGGVESLVSQPFSMTHASIPLEKRLANGITPQLIRLSVGIEDPHDLIADWQQALRRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-81 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-82 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-58 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_001337036.1 putative cystathionine gamma-synthase BAC0207 Protein 6e-66 45