Gene Information

Name : phoB (KPN_00340)
Accession : YP_001334022.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Resistance
Product : transcriptional regulator PhoB
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 380059 - 380748 bp
Length : 690 bp
Strand : +
Note : two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB

DNA sequence :
ATGGCGAGAAGAATTCTGGTCGTTGAAGATGAAGCTCCAATCCGCGAAATGGTCTGCTTTGTTCTGGAGCAAAATGGCTT
TCAGCCTGTCGAAGCGGAAGATTATGACAGCGCGGTGAATCAACTCAATGAACCCTGGCCTGATTTGATTCTCCTGGACT
GGATGCTGCCGGGCGGTTCGGGGCTGCAGTTTATTAAACTGCTCAAGCGCGAGGCGATGACGCGGGATATTCCGGTAGTG
ATGCTGACCGCGCGTGGAGAAGAAGAGGATCGCGTTCGCGGCCTGGAGACCGGCGCGGATGACTACATCACCAAGCCTTT
CTCTCCGAAAGAGCTGGTGGCGCGAATCAAAGCGGTGATGCGCCGTATTTCACCGATGGCGGTGGAAGAGGTGATCGAAA
TGCAGGGGCTGAGCCTCGACCCTTCATCGCACCGGGTAATGACCGGCGACAGTCCGCTGGATATGGGACCGACGGAATTT
AAATTATTGCACTTCTTTATGACCCATCCGGAGCGGGTGTACAGCCGCGAACAGCTGCTGAACCACGTCTGGGGGACCAA
CGTTTATGTGGAAGACCGCACGGTGGACGTCCATATTCGCCGCCTGCGCAAAGCGCTGGAACACAGTGGCCATGATCGTA
TGGTGCAAACGGTTCGCGGCACGGGGTATCGTTTCTCCGCCCGTTTCTGA

Protein sequence :
MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGLQFIKLLKREAMTRDIPVV
MLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPSSHRVMTGDSPLDMGPTEF
KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEHSGHDRMVQTVRGTGYRFSARF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDB402_0209 YP_005126722.1 two-component system response regulator Not tested Not named Protein 8e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoB YP_001334022.1 transcriptional regulator PhoB HE999704.1.gene2815. Protein 4e-39 43
phoB YP_001334022.1 transcriptional regulator PhoB CP000647.1.gene2531. Protein 7e-34 42
phoB YP_001334022.1 transcriptional regulator PhoB CP001918.1.gene3444. Protein 4e-33 41
phoB YP_001334022.1 transcriptional regulator PhoB BAC0596 Protein 2e-33 41
phoB YP_001334022.1 transcriptional regulator PhoB CP000034.1.gene2186. Protein 1e-32 41
phoB YP_001334022.1 transcriptional regulator PhoB NC_002695.1.916589.p Protein 8e-33 41
phoB YP_001334022.1 transcriptional regulator PhoB CP001138.1.gene2239. Protein 2e-33 41
phoB YP_001334022.1 transcriptional regulator PhoB BAC0039 Protein 1e-32 41