Gene Information

Name : tktA (KPN_03357)
Accession : YP_001336984.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 3675760 - 3677754 bp
Length : 1995 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCTCACGTAAAGAGCTTGCTAACGCTATTCGTGCGCTGAGCATGGACGCTGTACAGAAAGCCAAATCCGGCCACCC
GGGGGCCCCGATGGGTATGGCTGACATTGCCGAAGTGCTGTGGCGTGATTTCCTGAACCATAACCCGAACAATCCGGCCT
GGGCTGACCGTGACCGTTTTGTGTTGTCAAATGGCCATGGTTCGATGCTGATTTACAGCCTGCTGCACCTCACTGGCTAC
GATCTGCCGATTGAAGAGCTGAAAAACTTCCGCCAGCTGCACTCCAAAACCCCGGGTCACCCGGAAGTCGGCTACACCGC
AGGCGTGGAAACCACCACCGGTCCGCTGGGCCAGGGTATCGCTAACGCGGTCGGGATGGCTATCGCCGAGAAAACCCTGG
CGGCGCAGTTCAACCGTCCGGGACACGATATCGTCGACCACTACACCTACGCCTTCATGGGCGACGGCTGCATGATGGAA
GGCATTTCTCACGAAGTGTGCTCCCTGGCCGGTACCCTGAAACTGGGTAAACTGGTGGCGTTCTATGATGACAACGGCAT
CTCCATCGACGGCCACGTTGAAGGCTGGTTCACCGACGACACCGCCAAACGCTTTGAAGCCTACGGCTGGCACGTGGTGC
GCGGCGTGGACGGTCACGACGCTGACGCCATCAAACGCGCGGTAGAAGAAGCGCGGGCGGTCACCGACAAACCGTCCCTG
CTGATGTGTAAAACCATCATCGGTTTCGGTTCGCCGAACAAAGCCGGTACCCACGACTCCCACGGCGCGCCGCTGGGCGA
CGCCGAAATCGCCCTGACCCGCGAAGCGCTGGGCTGGAAACACGCGCCGTTTGACATCCCGTCTGACATCTATGCCCAGT
GGGATGCCAAAGAAGCCGGCCAGGCGAAAGAAGCCGCATGGAACGAGAAGTTTGCGGCTTACGCCAAAGCCTTCCCGCAG
GAAGCAGCCGAATTCACCCGCCGTATGAAAGGCGAGATGCCGTCTGACTTCGACGCGAAAGCTAACGAGTTCATCGCGAA
GCTGCAGGCCAACCCGGCGAAAATCGCCAGCCGTAAAGCCTCGCAGAACGCCATCGAAGCCTTCGGCCCGCTGCTGCCGG
AATTCCTCGGCGGCTCCGCAGATCTCGCGCCGTCCAACCTGACCCTGTGGTCCGGCTCTAAGCCGATCAACGAAGACGCT
GCCGGGAACTACATCCACTACGGCGTGCGCGAGTTCGGTATGACCGCTATCGCCAACGGTATCGCGCTGCACGGCGGCTT
CCTGCCGTACACCTCCACCTTCCTGATGTTCGTGGAATACGCGCGTAACGCGGTACGTATGGCCGCGCTGATGAAACAGC
GTCAGGTGATGGTCTACACCCACGACTCGATCGGTCTGGGCGAAGACGGCCCGACTCACCAGCCGGTAGAGCAGGTGGCT
TCCCTGCGCGTGACCCCGAACATGTCCACCTGGCGTCCGTGTGACCAGGTTGAATCCGCGATTGCGTGGAAATATGGCGT
GGAGCGTCAGGACGGCCCGACCGCGCTGATCCTCTCCCGTCAGAACCTGGCGCAGCAGGAGCGTACCGCAGAGCAGCTGG
CGAACGTGGCCCGCGGCGGTTATGTGCTGAAAGAGTGCACCGGCTCGCAGCCGGAGCTGATCTTCATCGCCACCGGTTCA
GAAGTGGAGCTGGCGGTTGCCGCATGGGACAAACTGACTGCCGAAGGCGTGAAGGCGCGCGTGGTTTCCATGCCGTCCAC
CGACGCGTTCGACAAGCAGGATGCGGCTTATCGCGAATCCGTACTGCCGAAAGCCGTGACCGCGCGCGTTGCCGTGGAAG
CGGGTATCGCTGACTACTGGTTCAAATACGTTGGCCTGAACGGCGCTATCGTTGGCATGACCACCTTCGGTGAGTCTGCG
CCGGCTGAGCAGCTGTTCGAGGAGTTCGGCTTCACCGTTGATAACGTGGTCGCTAAAGCGAAAGCGCTGCTGTAA

Protein sequence :
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLNHNPNNPAWADRDRFVLSNGHGSMLIYSLLHLTGY
DLPIEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
GISHEVCSLAGTLKLGKLVAFYDDNGISIDGHVEGWFTDDTAKRFEAYGWHVVRGVDGHDADAIKRAVEEARAVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREALGWKHAPFDIPSDIYAQWDAKEAGQAKEAAWNEKFAAYAKAFPQ
EAAEFTRRMKGEMPSDFDAKANEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKPINEDA
AGNYIHYGVREFGMTAIANGIALHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQVA
SLRVTPNMSTWRPCDQVESAIAWKYGVERQDGPTALILSRQNLAQQERTAEQLANVARGGYVLKECTGSQPELIFIATGS
EVELAVAAWDKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWFKYVGLNGAIVGMTTFGESA
PAEQLFEEFGFTVDNVVAKAKALL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 82
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68