Gene Information

Name : arsB (KPN_03304)
Accession : YP_001336932.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Resistance
Product : Ars family arsenical pump
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 3625438 - 3626730 bp
Length : 1293 bp
Strand : -
Note : -

DNA sequence :
ATGTTGCTGGCAGGTACGATTTTTATCCTGACCCTGGTGCTGGTGATCTGGCAGCCGCGGGGGTTAGGGATCGGCTGGAG
CGCGGCATTTGGCGCGGCGCTGGCGCTGGCCACCGGTGGCGTACAGGTAGCCGATATCCCGGTGGTATGGCATATCGTCT
GGAATGCGACCGCCACCTTTATCGCCGTTATCATTATCAGCCTGCTGCTTGATGAGTCTGGCTTTTTCGAATGGGCCGCG
CTGCACGTTTCCCGCTGGGGAAGAGGCCGGGGTCGTCTGCTGTTTACCTGGATTATCCTGCTCGGCGCGGCGGTGGCGGC
GCTGTTTGCCAACGATGGGGCGGCGCTGATCCTCACGCCAATCGTGATTGCCATGCTGCGAGCGCTGGGGTTCAGCAAGA
GAACGATGCTGGCCTTTGTCATGGCCGCCGGATTTATTGCCGATACCGCCAGCCTGCCGCTGGTGGTGTCGAATCTGGTG
AATATCGTTTCGGCAGATTTCTTTGCCATCGGCTTCAGGGAGTACGCTTCGGTGATGGTGCCGGTCGATCTCGCGGCGAT
CCTCACCACCCTGGCGATGCTGCACCTGTTCTTTCGCAAGGATATCCCGCCGGCCTGGGATATGGCGTTACTAAAAGCGC
CGGCCACGGCGATAAAAGATCCAGCGACGTTCCGCACCGGCTGGGGCGTGCTGCTGCTGTTGCTGGCTGGCTTTTTCGTC
CTTGAACCGCTGGGGATCCCGGTCAGCGCCATCGCGGCGCTCGGTGCCGGGATCCTGTTTGTTGTCGCGAAGCGCGGGCG
GGTAATTAACACCGGCAAGGTGCTGCGCGGCGCCCCGTGGCAGATAGTGATCTTCTCGCTGGGAATGTATCTGGTGGTGT
ATGGTCTGCGAAACGCCGGGTTAACGGATTATCTGACCACGGTGCTGAACATGCTGGCGGAGCGCGGGCTCTGGGCCGCG
ACGCTGGGCACCGGTATCCTGTCGGCCTTCCTCTCTTCAATAATGAATAATATGCCCAGCGTACTGGTCGGCGCCCTGTC
GATTGATGGCAGCGCGGCAACAGGGACGATCAAAGAGGCCATGATTTATGCCAACGTCATCGGCTGCGATCTGGGGCCCA
AGATCACGCCAATTGGTAGCCTGGCCACGCTGCTGTGGCTGCATGTGCTGGCGCAGAAGCACATCACCATCGGTTGGGGG
TATTATTTCCGCTGCGGCATCACCATGACCCTGCCGGTGCTGCTTGTGACGCTGGCCGCGCTGGCGCTGCGTCTCTCCTT
CAACCAGCCATGA

Protein sequence :
MLLAGTIFILTLVLVIWQPRGLGIGWSAAFGAALALATGGVQVADIPVVWHIVWNATATFIAVIIISLLLDESGFFEWAA
LHVSRWGRGRGRLLFTWIILLGAAVAALFANDGAALILTPIVIAMLRALGFSKRTMLAFVMAAGFIADTASLPLVVSNLV
NIVSADFFAIGFREYASVMVPVDLAAILTTLAMLHLFFRKDIPPAWDMALLKAPATAIKDPATFRTGWGVLLLLLAGFFV
LEPLGIPVSAIAALGAGILFVVAKRGRVINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLTTVLNMLAERGLWAA
TLGTGILSAFLSSIMNNMPSVLVGALSIDGSAATGTIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKHITIGWG
YYFRCGITMTLPVLLVTLAALALRLSFNQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 5e-150 86
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 4e-99 58
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 3e-97 56
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 6e-100 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_001336932.1 Ars family arsenical pump BAC0576 Protein 4e-150 86
arsB YP_001336932.1 Ars family arsenical pump BAC0578 Protein 8e-151 86
arsB YP_001336932.1 Ars family arsenical pump BAC0031 Protein 6e-150 85
arsB YP_001336932.1 Ars family arsenical pump BAC0577 Protein 2e-149 84
arsB YP_001336932.1 Ars family arsenical pump BAC0574 Protein 2e-98 57
arsB YP_001336932.1 Ars family arsenical pump BAC0575 Protein 1e-100 56