Gene Information

Name : sitC (KPN_03080)
Accession : YP_001336711.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : iron transporter: fur regulated
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 3377237 - 3378085 bp
Length : 849 bp
Strand : +
Note : -

DNA sequence : 
ATGAGCTGGCTGCTGGAGCCGTTTGGCTATCACTATATGCTCAATGCGATGTGGGTGTCGGCGCTGGTGGGCGGCGTCTG
CGCCTTTCTCTCCTGCTACCTGATGCTCAAAGGCTGGTCGCTGATTGGCGACGCCCTCTCCCACTCGATTGTACCCGGCG
TCGCCGGGGCCTATATGCTCGGCCTGCCCTTCGCGCTCGGCGCATTTCTCTCCGGCAGTCTGGCGGCAGGCAGCATGCTG
TTTTTGCAACAGCGCTCGCGGCTAAAAGAGGATGCTATTATCGGGCTGATCTTCTCCTCCTTCTTCGGGATCGGGCTGTT
TATGGTGTCGCTGAATCCGACGTCGGTGAATATCCAGACCATCATCCTCGGCAATATTCTGGCCATCGCCCCGGAGGATA
TTATCCAGCTGGCGGCGATCGGCTTTATCTCAATGGCGATTCTGCTGCTGAAATGGAAAGACCTGATGGTGACCTTCTTT
GATGAACACCATGCCCGCTCGATTGGCCTGAACACCCGCGGCCTGAAGCTGCTGTTCTTTACCCTGCTGGCCGCCTGCAC
CGTGGCGGCGCTGCAGACCATCGGCGCCTTTCTGGTCATCTGCGTGGTGGTCACTCCCGGGGCTACCGCGTGGTTGTTAA
CCGATCGCTTCCCGCGCCTGCTGGCTATCGCCGTGTCTATCGGCAGCCTGACCAGTTTCTTCGGCGCCTGGCTCAGCTAC
TATCTCGACGGCGCCACCGGCGGCATTATCGTGGTCGCGCAAACGCTGCTGTTCCTCATCACCTTTATCTTCGCGCCGAA
GCACGGCCTGCTGGCCAGCCGCCGCCGCGCCAGGGAGGCCGCATGCTGA

Protein sequence : 
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGSLAAGSML
FLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFF
DEHHARSIGLNTRGLKLLFFTLLAACTVAALQTIGAFLVICVVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 6e-86 87
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 6e-86 87
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 5e-86 87
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 7e-86 87
sitC NP_461784.1 permease Virulence SPI-1 Protein 7e-86 87
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 4e-37 43
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 1e-36 43
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 1e-36 43
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-36 43
sitD NP_461785.1 permease Virulence SPI-1 Protein 6e-37 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC YP_001336711.1 iron transporter: fur regulated BAC0351 Protein 3e-86 87
sitC YP_001336711.1 iron transporter: fur regulated BAC0441 Protein 4e-68 69
sitC YP_001336711.1 iron transporter: fur regulated BAC0352 Protein 3e-37 43
sitC YP_001336711.1 iron transporter: fur regulated BAC0442 Protein 4e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC YP_001336711.1 iron transporter: fur regulated VFG0527 Protein 3e-86 87
sitC YP_001336711.1 iron transporter: fur regulated VFG0528 Protein 2e-37 43