Gene Information

Name : nrdF (KPN_03007)
Accession : YP_001336643.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 3305517 - 3306479 bp
Length : 963 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACCCATTTAACGCGCGTCAGCGCAATCAACTGGAACCGCATTGATGACGATAAAGATCTTGAGGTCTGGAACCGTCT
CACCAGCAACTTCTGGCTGCCGGAGAAAGTGCCGCTGTCGAACGACATTCCCGCCTGGCAAACCCTCAGCGCGGCGGAGC
AGCAGTTGACCATTCGCGTCTTTACCGGATTGACCCTGCTTGACACCATTCAGAACACCGTCGGCGCCCCGGCGCTAATG
GCGGACGCCTTAACCCCGCATGAGGAGGCGGTGCTGTCGAACATCAGCTTTATGGAGGCGGTTCATGCCCGCTCTTACAG
CTCCATCTTTTCCACGCTGTGCCACAGCAAGGAAGTGGATGCCGCCTTCGCCTGGAGCGAAAGCTGCGATCCCCTGCAGC
GCAAGGCGCAGCTGATGCTGGATTACTATCAGGCCGACGAGCCGCTGAAGAAAAAAATCGCCAGCGTGTTCCTCGAATCC
TTTCTCTTCTACTCCGGCTTCTGGCTGCCGATGTACTTCTCCAGCCGGGGAAAGCTGACCAACACTGCGGATCTGATCCG
CCTGATCATTCGCGATGAAGCGGTGCATGGCTATTACATCGGCTACAAGTACCAGAAAGGACTGGAGATCGTCAGCCCCG
GCAAGCGCGAAGAATTGAAAAATTTCGCCCTCGATCTGCTGATGGATCTTTACGACAACGAACTGGCCTACAGCCGGGAG
CTGTACGGCGAGAGCGGCTGGTTCGACGACGTCAGCGCTTTCCTGTGCTACAACGCCAACAAAGCGCTGATGAACCTCGG
CTACGAGGCGCTGTTCCCGGCGGAGATGGCGGCGGTCAATCCGGCAATCCTCGCAGCGCTGTCGCCCAACGCCGACGAAA
ACCATGACTTTTTCTCCGGTTCCGGCTCCTCCTACGTGATAGGAAAAATGGAAGAGACCGCCGACGACGATTGGGACTTT
TAA

Protein sequence :
MTHLTRVSAINWNRIDDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQLTIRVFTGLTLLDTIQNTVGAPALM
ADALTPHEEAVLSNISFMEAVHARSYSSIFSTLCHSKEVDAAFAWSESCDPLQRKAQLMLDYYQADEPLKKKIASVFLES
FLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKGLEIVSPGKREELKNFALDLLMDLYDNELAYSRE
LYGESGWFDDVSAFLCYNANKALMNLGYEALFPAEMAAVNPAILAALSPNADENHDFFSGSGSSYVIGKMEETADDDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-105 67