Gene Information

Name : aldB (KPN_02991)
Accession : YP_001336627.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : lactaldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 3290475 - 3291995 bp
Length : 1521 bp
Strand : -
Note : -

DNA sequence :
ATGCGTTATGCACATCCTGGCCAGCCCGGCGCCGTGGTTTCATTTAAATCGGCTTACGGCAACTTTATTGACGGTAGATT
TGTCGAGCCGCTGAGCGGTGAATTCTTTATGAATACTTCGCCGGTCGACGGCAGCAACATTGCGCAGTTTCCCCGCTCGG
ATGCCAGAGACATTGACTTCGCCCTCGACGCCGCCCATCGCGCGGCGCCGGCGTGGGGTAAAACCTCAGTGCAACAGCGC
TCCAGGCTGCTGCTGCAGGTCGCCGATCGTATTGAACAGCATCTGGAATATCTGGCGGTGGCGGAGAGCTGGGACAATGG
GAAACCGATCCGCGAAACGCTTAACGCCGACCTGCCGCTGGCGGTGGACCATTTTCGCTACTTCGCCGGCTGCCTGCGCG
CCCAGGAGGGTAGTACCGCCGAAATTGACGAAACCACGGTGGCCTATCATTTCCATGAACCGCTGGGGGTGGTCGGACAG
ATTATCCCGTGGAACTTCCCGCTGCTGATGGCCGCGTGGAAGCTGGCCCCGGCCCTGGCGGCGGGGAACTGCGTGGTGCT
CAAACCGGCGGAACAGACGCCGCTAAGCATTACCCTGCTGCTGGAGCTGATCGGCGATCTGTTCCCGGCCGGGGTGCTTA
ACGTGGTGCAGGGTTTCGGCAAAGAGGCGGGCGAGGCGCTGGCCACCAGCAAGCGTATCGCCAAGCTGGCGTTTACCGGC
TCCACGCCGGTCGGGCGGCATATTCTCGCCTGCGCGGCGGAAAATATTATCCCCTGCACCGTCGAGCTGGGGGGGAAATC
GCCCAACATCTACTTCGCCGACGTGATGGACGGAGAAGAGGAATTTATTGAGAAGGCGGTGGAGGGGCTGGTGCTCGGCT
TCTTCAACCAGGGTGAGGTCTGTACCTGCCCGTCGCGGGCGCTGATCCATGAATCCATCTATGAGCCCTTTATGGCACGG
GTAATGGAGAAGGTGGCGCAGATCCGCCGCGGCGATCCGTTAGATACCGACACCATGATCGGCGCTCAGGCTTCCCGCCA
GCAGTTCGATAAGATCCTCTCCTATATTCAGATTGCCCGGGAAGAGGGTGGGCAAATACTGACCGGCGGCGAACGGGCGG
CTATCGCGCCGGCGCTGGATAATGGCTTTTATATTCAGCCCACGCTGATTAAAGGTCGCAACGATATGCGCTCCTTCCAG
GAGGAGATCTTTGGGCCGGTGATCGGGGTGACCACCTTTAAGGACGAAGCGGAAGCGCTGGCTATCGCCAATGAGACCCA
GTTTGGTCTCGGCGCCGGGGTGTGGACGCGGGATACCAACCTCGCCTATCGCATGGGTCGCGGCATTAAAGCCGGTCGCG
TGTGGACCAACTGCTATCATGTCTACCCGGCGCATGCGGCGTTCGGCGGCTATAAACAGTCCGGCGTCGGCCGGGAAACG
CACAAGATGGCGCTGGATGCCTATCAGCAAACCAAAAACCTGCTGGTGAGCTACGGCACCGCGCCGCTGGGCCTGTTCTG
A

Protein sequence :
MRYAHPGQPGAVVSFKSAYGNFIDGRFVEPLSGEFFMNTSPVDGSNIAQFPRSDARDIDFALDAAHRAAPAWGKTSVQQR
SRLLLQVADRIEQHLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLELIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKLAFTG
STPVGRHILACAAENIIPCTVELGGKSPNIYFADVMDGEEEFIEKAVEGLVLGFFNQGEVCTCPSRALIHESIYEPFMAR
VMEKVAQIRRGDPLDTDTMIGAQASRQQFDKILSYIQIAREEGGQILTGGERAAIAPALDNGFYIQPTLIKGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALAIANETQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALDAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-154 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-161 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-161 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-161 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-160 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-57 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_001336627.1 lactaldehyde dehydrogenase VFG0082 Protein 5e-155 66