Gene Information

Name : clpB (KPN_02915)
Accession : YP_001336551.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : protein disaggregation chaperone
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3204883 - 3207456 bp
Length : 2574 bp
Strand : -
Note : part of multi-chaperone system with DnaK, DnaJ, and GrpE

DNA sequence :
ATGCGTCTGGATCGTCTTACCAATAAATTCCAGCTTGCTCTTGCCGATGCCCAGTCGCTCGCACTCGGGCACGACAACCA
ATTCATCGAACCTCTTCATTTAATGAGCGCCTTGCTGAATCAGGAAGGGGGATCGGTACGTCCTTTATTAACCTCGGCGG
GCGTGAATGCCGGGAAACTGCGCACTGACATCGAACAGGCCTTGAGCCGTTTACCGCAGGTGGAAGGCACCGGCGGCGAT
GTGCAACCTTCTCAGGATTTAGTGCGGATCCTCAACCTTTGCGACAAGCTGGCGCAAAAGAAAAAGGACAACTTTATTTC
GTCGGAACTGTTCGTTCTGGCGGCGCTTGAATCGCGCGGTACGCTGACCGACCTTTTAAAATCCGCCGGAGCAACAACCG
CCAACGTGACTCAGGCGATTGAACAAATGCGCGGAGGTGAAAGCGTGAACGATCAGGGTGCCGAAGACCAACGTCAGGCA
TTGAAGAAATTTACCGTCGATCTGACCGAGCGAGCCGAGCAGGGCAAGCTGGATCCGGTGATCGGCCGTGATGAAGAGAT
TCGCCGTACCATTCAGGTACTGCAGCGTCGTACCAAAAACAACCCGGTGCTGATCGGTGAACCCGGGGTGGGTAAAACGG
CAATCGTCGAAGGCCTGGCGCAGCGTATCGTCAACGGCGAAGTACCAGAAGGGCTGAAAGGCCGTCGGGTATTGGCGCTG
GATATGGGGGCGCTGGTGGCCGGGGCGAAATACCGCGGTGAGTTTGAAGAGCGTCTGAAAGGCGTGCTGACCGACCTGTC
CAAACAGGAAGGCAACGTCATTCTGTTTATCGACGAACTGCATACCATGGTTGGCGCTGGTAAAGCCGACGGCGCGATGG
ATGCGGGTAACATGCTGAAGCCGGCGCTGGCGCGTGGTGAACTGCACTGCGTCGGGGCGACGACGCTTGATGAATACCGT
CAGTACATCGAAAAAGACGCCGCGCTGGAACGTCGCTTCCAGAAAGTGTTCGTTGCCGAGCCTTCGGTAGAAGATACCAT
CGCGATTCTGCGCGGTCTGAAAGAACGTTATGAGCTGCACCACCACGTGCAGATCACTGACCCGGCTATCGTGGCGGCGG
CGACCTTATCGCATCGCTATATTGCCGACCGTCAGCTGCCGGATAAAGCCATCGACCTCATCGATGAGGCGGCATCCAGC
ATCCGTATGCAGATTGACTCCAAACCGGAAGAGCTGGACCGTCTCGATCGGCGTATTATCCAGCTGAAACTGGAACAGCA
GGCGCTGAAGAAAGAGTCTGATGAGGCGAGCCTGAAGCGTCTCGATATGCTCAACGAGGAGCTGGCGGATAAAGAACGGC
AGTACTCGGTGCTGGAAGAAGAGTGGAAAGCGGAAAAAGCGTCGCTCTCCGGCACCCAGACCATCAAAGCTGAGCTGGAG
CAGGCGAAAATCGCCATCGAACAGGCGCGCCGCGTCGGCGATCTGGCGCGGATGTCCGAGCTGCAGTATGGCAAAATTCC
GGAACTGGAGAAACAGCTGGCGGCTGCCACTCAGTCCGAAGGGAAAACCATGCGTCTGCTGCGTAATAAAGTGACGGATG
CTGAAATCGCCGAAGTGCTGGCTCGCTGGACCGGTATCCCGGTCTCCCGCATGATGGAAAGCGAGCGTGACAAACTGCTG
CGTATGGAGCAGGAGCTGCATCATCGGGTGATTGGCCAGGATGAGGCGGTTGAAGCGGTATCCAACGCCATTCGCCGCAG
CCGCGCCGGGCTGTCCGATCCGAACCGGCCGATTGGTTCGTTCCTGTTCCTCGGTCCAACCGGGGTCGGTAAAACCGAGC
TGTGTAAAACGCTGGCTAACTTTATGTTCGACAGCGACGACGCAATGGTGCGTATCGATATGTCCGAGTTTATGGAGAAA
CATTCCGTCTCGCGTCTGGTCGGTGCGCCTCCGGGATACGTCGGCTATGAAGAGGGCGGTTACCTGACCGAGGCGGTGCG
CCGTCGTCCTTATTCCGTCATCCTGCTGGATGAAGTGGAAAAAGCGCACCCGGATGTGTTCAACATTCTGCTGCAGGTAC
TCGACGACGGGCGTCTCACCGACGGGCAGGGGAGAACGGTCGACTTCCGTAATACGGTAGTCATCATGACCTCGAACCTC
GGTTCCGATCTGATTCAGGAACGGTTCGGCGAGCTGGACTACGGACATATGAAGGACCTGGTGCTGGGGGTAGTCAGCCA
GAACTTCCGTCCGGAGTTCATCAACCGTATCGACGAAGTGGTGGTCTTCCATCCGCTGGGCGAGAAACATATTGCCTCTA
TTGCCCAGATCCAGCTGCAGCGTCTGTATAAACGTCTGGAAGAGCGCGGATATGAAGTGCAGATGTCCGATGAGGCGCTG
AAGCTGCTGAGCGCCAACGGTTACGATCCGGTATACGGCGCGCGGCCATTGAAACGTGCTATTCAGCAGCAGATTGAGAA
CCCGTTAGCCCAGCAGATCCTTTCCGGTGAGCTGGTTCCGGGTAAAACCATCGAGCTGGTAGTAAAAGACGACCGCATTG
TGGCAGTGCAGTAA

Protein sequence :
MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVRPLLTSAGVNAGKLRTDIEQALSRLPQVEGTGGD
VQPSQDLVRILNLCDKLAQKKKDNFISSELFVLAALESRGTLTDLLKSAGATTANVTQAIEQMRGGESVNDQGAEDQRQA
LKKFTVDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKGRRVLAL
DMGALVAGAKYRGEFEERLKGVLTDLSKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASS
IRMQIDSKPEELDRLDRRIIQLKLEQQALKKESDEASLKRLDMLNEELADKERQYSVLEEEWKAEKASLSGTQTIKAELE
QAKIAIEQARRVGDLARMSELQYGKIPELEKQLAAATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESERDKLL
RMEQELHHRVIGQDEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFMFDSDDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQERFGELDYGHMKDLVLGVVSQNFRPEFINRIDEVVVFHPLGEKHIASIAQIQLQRLYKRLEERGYEVQMSDEAL
KLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKTIELVVKDDRIVAVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-102 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-97 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 8e-98 41