Gene Information

Name : tktB (KPN_02799)
Accession : YP_001336439.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 3066150 - 3068144 bp
Length : 1995 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCCGAAGAGAGCTTGCCAACGCCATCCGCGCCCTGAGTATGGACGCCGTGCAGAAAGCCAACTCCGGCCACCCCGG
TGCGCCGATGGGGATGGCTGATATTGCCGAAGTGCTGTGGAACGATTTTCTCAAGCACAATCCGCAGAACCCTGACTGGG
TGGACCGCGACCGTTTCATCTTGTCCAACGGCCACGCGTCGATGCTGCTCTACAGTCTGCTGCACCTGACCGGCTACGAT
CTGCCGCTGTCTGAACTGAAGCAGTTCCGTCAGCTGCACTCTAAAACGCCCGGCCACCCGGAGCATGGCTATACCCCTGG
GGTGGAAACCACCACCGGCCCGCTGGGCCAGGGGCTGGCGAACGCCGTCGGGATGGCCATCGCCGAACGGACGCTGGCGG
CGCAGTTTAATCGCCCCGGCCATGAGATCATTGACCATCACACCTGGGTGTTCATGGGCGATGGCTGTTTGATGGAGGGG
ATCTCCCATGAGGCCTGTTCGCTGGCCGGCACGCTCGGACTGGGCAAGCTGATCGGTTTTTACGATCACAACGGCATCTC
CATCGACGGCAAAACCGAAGGCTGGTTTTCCGATGATACGGCGGAACGCTTCCGCGCCTATCACTGGCACGTCATAGGCG
ATATCGACGGCCACGATCCGCAGGCTATCAAACAGGCGATAACGGAAGCGCAGGCGGTGAAAGATAAACCGTCACTGATT
ATCTGCCGGACCATCATCGGCTTCGGTTCGCCCAACAAAGCCGGCTCAGAGGAGTCTCACGGGGCGGCGCTTGGCGAAAA
AGAGGTAGCGCTAGCCCGCCAGCAGCTTGGCTGGAAATATCCTCCGTTCGAGATCCCGAAAGAGATCTACGCGGGCTGGG
ATGCGCGTCCGCGCGGGGAAAAAGCGGAGCACGCCTGGAACGAGAAATTCGCCGCCTACCAGCAGCAGTTCCCGGAGCTG
GCCGCTGAGCTGACCCGACGTATGAATGGCGCCCTGCCGGAAGACTTTGCCGCGACCGCCCGCGACTACGTGGCGAAACT
GCAGGCCGAGCCGGCGAAAATCGCCAGTCGCAAGGCTTCGCAAAACGCGCTGAACGCCTACGGCCCGCACCTTCCGGAAC
TGCTGGGCGGTTCTGCGGATCTTGCGCCGAGTAACCTGACCATCTGGTCTGGATCGACATCGATTAAAGAAGATCCTGCG
GGCAATTATATCCACTACGGGGTGCGCGAGTTTGGCATGACCGCGGTGGCCAACGGCATTGCCCTGCACGGGGGCTTTAT
TCCTTATACCTCGACCTTCCTGATGTTTGTGGAGTACGCCCGCAACGCCGCGCGCATGGCGGCCCTGATGAAGGCCCGGC
AGATCATGGTCTATACCCATGACTCGATCGGTCTTGGGGAAGACGGGCCGACGCACCAGGCGGTGGAACAGCTGGCCAGT
CTGCGGCTGACGCCCAACTTCAGCACCTGGCGCCCCTGCGACCAGGTGGAGACCGCCGTCGCCTGGCAGGCGGCTATCGC
GCGACAGGGCGGGCCGACGGCGCTGATCCTGTCGCGACAAAACCTGGCGCAGATGCCGCGTACCCCGGAACAGGTGCAGG
ATATCGCCCGGGGTGGCTACGTGCTTAAGGATGCCGGCGGAAAACCCGACCTGATCCTCATCGCCACCGGCTCGGAAGTG
GAGATCACCGTCCTGGCCGCGGAAAAACTGTTGGCCAAAGGGGTAAATGTGCGGGTCGTCTCGCTCCCTTCCACTGATGT
GTTTGACGCCCAGGATGAGGCCTGGCGCGAATCGGTGCTGCCGTCGGACGTCAGCGCCCGGGTGGCGGTCGAAGCCGGGA
TAGCGGACTACTGGTATAAATATGTCGGCTTAAAAGGCAAGATCGTCGGCATGACCGGCTATGGCGAATCCGCCCCGGCA
GAGCAGTTGTTCCCGTTCTTTGGCTTTACGGTCGACCATATCGTCGCCACCGCCGAACAGGTGCTTAACGGGTGA

Protein sequence :
MSRRELANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPQNPDWVDRDRFILSNGHASMLLYSLLHLTGYD
LPLSELKQFRQLHSKTPGHPEHGYTPGVETTTGPLGQGLANAVGMAIAERTLAAQFNRPGHEIIDHHTWVFMGDGCLMEG
ISHEACSLAGTLGLGKLIGFYDHNGISIDGKTEGWFSDDTAERFRAYHWHVIGDIDGHDPQAIKQAITEAQAVKDKPSLI
ICRTIIGFGSPNKAGSEESHGAALGEKEVALARQQLGWKYPPFEIPKEIYAGWDARPRGEKAEHAWNEKFAAYQQQFPEL
AAELTRRMNGALPEDFAATARDYVAKLQAEPAKIASRKASQNALNAYGPHLPELLGGSADLAPSNLTIWSGSTSIKEDPA
GNYIHYGVREFGMTAVANGIALHGGFIPYTSTFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGEDGPTHQAVEQLAS
LRLTPNFSTWRPCDQVETAVAWQAAIARQGGPTALILSRQNLAQMPRTPEQVQDIARGGYVLKDAGGKPDLILIATGSEV
EITVLAAEKLLAKGVNVRVVSLPSTDVFDAQDEAWRESVLPSDVSARVAVEAGIADYWYKYVGLKGKIVGMTGYGESAPA
EQLFPFFGFTVDHIVATAEQVLNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 71
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 66