Gene Information

Name : uvrY (KPN_02412)
Accession : YP_001336065.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 2635906 - 2636613 bp
Length : 708 bp
Strand : -
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence :
GTGGGAGATAAAGTATCAGTAGCGTTATCCCTCATTCTGGAGATTATTCCTTTGATCAACGTTCTTCTTGTTGATGACCA
CGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAAGGGATTAAAGTCGCTGGCGAAGCCTGCTGCGGCG
AGGACGCCGTCAAGTGGTGCCGGGCTAATTCCGCAGATGTCGTCCTGATGGACATGAACATGCCTGGGATCGGTGGTCTT
GAAGCGACGCGCAAAATCGCGCGCTCCGTGGCGGGCACCAAAGTGATCATGTTGACCGTGCATACCGAGAATCCTTTACC
TGCCAAGGTCATGCAGGCGGGCGCGGCAGGCTATCTCAGTAAAGGCGCCGCGCCGCAGGAAGTGGTGAATGCCATCCGCT
GCGTCGCGTCCGGGCAGCGCTATATTGCCTCCGATATTGCCCAGCAAATGGCGTTAAGTCAGATTGAACCCGAAAAGACA
GAATCGCCGTTTGCCAGTTTGTCTGAACGCGAATTGCAGATTATGCTGATGATCACCAAAGGTCAGAAGGTGAATGAGAT
CTCAGAGCAGCTAAATCTGAGTCCTAAAACGGTTAACAGCTACCGCTATCGGATGTTCAGTAAATTAAACATTCATGGCG
ATGTCGAGCTGACCCACCTGGCAATTCGCCATGGCCTGTGTAATGCGGAGTCGTTAGCAAGCCAGTGA

Protein sequence :
MGDKVSVALSLILEIIPLINVLLVDDHELVRAGIRRILEDIKGIKVAGEACCGEDAVKWCRANSADVVLMDMNMPGIGGL
EATRKIARSVAGTKVIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVNAIRCVASGQRYIASDIAQQMALSQIEPEKT
ESPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAESLASQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 1e-46 50
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 1e-46 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
uvrY YP_001336065.1 response regulator VFG1889 Protein 2e-54 52