Gene Information

Name : ycgO (KPN_02307)
Accession : YP_001335963.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 2528860 - 2530593 bp
Length : 1734 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGACGCCGCTGCGGTCATTAGTCTGTTTATTCTGGGTTCTGTTTTAGTAACCTGCAGTATCTTATTGAGCTCCTTTTC
TTCGCGCCTTGGCATCCCGATTCTGGTCATCTTTCTGGCCATCGGGATGCTGGCAGGCATTGACGGCATCGGCGGCATCC
CCTTCGACAACTACCCCTTCGCCTATATGGTGAGTAACCTGGCGCTGGCGGTGATCCTGCTGGATGGCGGGATGCGCACC
CAGGCCAGCTCCTTTCGCGTCGCGCTGTGGCCCGCGCTGTCGCTGGCGACGGTTGGGGTGCTGATCACCTCGGCGCTGAC
CGGGATGATGGCGGCCTGGTTGTTCAAGCTGGATCTGATCGAAGGCCTGCTGATCGGCGCCATTGTCGGCTCCACCGACG
CCGCGGCGGTCTTCTCGCTGCTCGGCGGCAAGGGGCTCAACGAGCGCGTCGGCTCGACGCTGGAGATAGAGTCAGGCAGT
AACGACCCGATGGCGGTCTTCCTGACCATCACCCTGATCGAAATGATCCAGCAGCACCAAACCGGCCTCAGCTGGATGTT
CGCCGTGCATATCATTCAGCAGTTCGGCCTCGGGATCGCCATCGGCCTCGGCGGCGGCTACCTGCTGCTGCAGATGATTA
ACCGCATCGTGCTGCCCGCCGGCCTCTATCCGCTGCTGGCGCTGAGCGGCGGGATCATGATTTTTGCCGTCACCACCTCC
CTCGACGGCAGCGGTATCCTCGCCGTCTATCTCTGCGGCTTTCTGCTGGGCAACCGGCCGATCCGCAACCGGCACGGCAT
CCTGCAGAACTTCGACGGCCTGGCGTGGCTGGCGCAGATCGCCATGTTCCTGGTGCTGGGCCTGCTGGTGACGCCCTCCG
ACCTGCTGCCGATCGCTATCCCGGCGCTGCTGCTGTCGATGTGGATGATATTCATTGCCCGGCCCCTGTCGGTGTTTGCC
GGCCTGCTGCCGTTTCGCGGCTTTAACCTGCGCGAACGGGTGTTTATCAGCTGGGTTGGCCTGCGCGGCGCGGTGCCCAT
TATTCTCGCGGTGTTCCCGATGATGGCCGGCCTGGACAACGCCCGCCTGTTCTTCAATGTCGCCTTCTTCGTGGTGCTGG
TGTCGCTGCTGCTGCAGGGCACTTCGCTGTCGTGGGCGGCGAAAAAAGCCAAAGTGGTGGTTCCGCCCATCAGCTGGCCC
ATCTCCCGCGTCGGGCTGGATATTCACCCGGAAAACCCGTGGGAGCAGTTTGTCTACCAGCTGGGGGCCGATAAGTGGTG
CATCGGCGCGGCGCTGCGCGACTTGCACATGCCACCGGAGACGCGGATTGCCGCGCTGTTTCGCAACAATGTCCTGCTGC
ACCCCACCGGCAGCACCCGCCTGCGGGAAGGCGATATCCTGTGCGTTATTGGTCGAGAGCACGACCTGCCGGCGCTGGGC
AAAATGTTCAGCCAGTCGCCGCCGGTGGCGCTCGATCAGCGCTTTTTCGGCGACTTCATTCTTGATGCTGAGGCCCGCTT
CGCCGATGTGGCGCAAATCTACGGTCTCGACGGCGGTGAGGAGTTCCGCGAGCATCAGCAGTCGCTCGGGGAAGTGGTGC
AGCAGCTGCTGGGCGCGGCGCCGGTGGTGGGCGACCAGGTGGAGTTCGCCGGGATGGTGTGGACGGTAGCTGAAAAAGAG
AACGATCACGTGCTGAAGGTTGGGGTGCGGGTCGCGGAAGACGAGGCGGAGTGA

Protein sequence :
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQQHQTGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTS
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAIPALLLSMWMIFIARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWP
ISRVGLDIHPENPWEQFVYQLGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALG
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAAPVVGDQVEFAGMVWTVAEKE
NDHVLKVGVRVAEDEAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 89
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 89