Gene Information

Name : pykF (KPN_02133)
Accession : YP_001335791.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2336860 - 2338272 bp
Length : 1413 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAAAAGACCAAAATTGTTTGCACCATCGGTCCGAAAACCGAATCTGAAGAGATGCTGACCAAAATGCTGGAAGCCGG
CATGAATGTGATGCGTCTGAACTTCTCCCACGGTGACTATGCGGAACACGGTCAGCGCATCCAGAACCTGCGCAATGTGA
TGAGCAAAACCGGTAAGAAAGCCGCTATTCTGCTGGACACCAAAGGGCCGGAAATTCGTACCATCAAGCTGGAAGGCGGC
AACGACGTCTCCCTGAAAGCAGGCCAGACCTTCACCTTCACTACCGATAAATCCGTCATCGGCAACAACGAAATCGTTGC
GGTAACCTATGAAGGCTTCACCTCTGACCTCGCCGTCGGCAACACCGTCCTGGTGGACGATGGCCTGATCGGCATGGAAG
TCACGGCTATCGAAGGCAACAAAGTTATCTGTAAAGTGCTGAACAATGGCGACCTCGGCGAGAACAAAGGCGTTAACCTG
CCGGGCGTCTCCATCGCCCTGCCGGCGCTGGCTGAGAAAGACAAACAGGATCTGATCTTCGGTTGCGAACAGGGCGTGGA
CTTCGTCGCGGCCTCCTTCATCCGTAAACGTTCCGACGTCGTCGAGATCCGTGAGCACCTGAAAGCCCACGGCGGCGAAA
ACATCCAGATCATCTCCAAAATCGAAAACCAGGAAGGCCTGAACAACTTCGACGAAATCCTCGAAGCGTCTGACGGCATC
ATGGTTGCGCGTGGCGACATGGGCGTGGAGATCCCGGTTGAAGAAGTTATCTTCGCCCAGAAAATGATCATCGAAAAATG
TATCCGCGCGCGTAAAGTGGTTATCACCGCCACCCAGATGCTGGACTCCATGATCAAGAACCCGCGTCCGACCCGCGCTG
AAGCCGGCGACGTGGCTAACGCCATCCTCGACGGCACCGATGCGGTGATGCTGTCCGGCGAATCCGCGAAAGGTAAATAC
CCGCTGGAAGCGGTCACCATCATGGCGACCATTTGCGAACGTACCGACCGCGTGATGACCAGCCGTCTGGACTTCAACAA
CGACAACCGTAAACTGCGCATCACCGAAGCGGTGTGCCGCGGCGCGGTAGAAACCGCTGAGAAACTGGAAGCGCCGCTGA
TCGTGGTCGCCACCCAGGGCGGTAAATCCGCACGCGCTGTGCGCAAATACTTCCCGGATGCCACCATCCTGGCGCTGACC
ACCAACGAAACCACCGCTCGTCAGCTGGTGCTGAGCAAAGGCGTGGTACCGCAGCTGGTGGAAGAGATTGCCTCTACCGA
TGATTTCTATCATCTGGGCAAAGACCTGGCGCTGAAGAGCGGCCTCGCGCGTAAAGGCGACGTAGTGGTGATGGTTTCCG
GCGCATTAGTGCCGAGCGGCACGACTAATACCGCTTCCGTACACGTGCTGTAA

Protein sequence :
MKKTKIVCTIGPKTESEEMLTKMLEAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKKAAILLDTKGPEIRTIKLEGG
NDVSLKAGQTFTFTTDKSVIGNNEIVAVTYEGFTSDLAVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI
MVARGDMGVEIPVEEVIFAQKMIIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY
PLEAVTIMATICERTDRVMTSRLDFNNDNRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALT
TNETTARQLVLSKGVVPQLVEEIASTDDFYHLGKDLALKSGLARKGDVVVMVSGALVPSGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 0.0 97
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 0.0 97
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 0.0 96
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 0.0 96

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_001335791.1 pyruvate kinase VFG0479 Protein 0.0 97