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Name : lysS (NWMN_0479) Accession : YP_001331513.1 Strain : Staphylococcus aureus Newman Genome accession: NC_009641 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 543965 - 545512 bp Length : 1548 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTTTGAGTGTACCAGTTGGAATACTAAAGGATTACAACAAGTTAAAGGAGAGAAAGTTATGTCAGAAGAAATGAATGA CCAAATGTTGGTTCGACGTCAAAAATTACAAGAATTATATGATCTTGGTATAGACCCGTTTGGTTCTAAATTTGACCGTT CAGGTTTATCTAGTGATTTGAAAGAAGAGTGGGACCAGTATTCTAAAGAAGAATTGGTAGAAAAAGAAGCGGATAGTCAT GTCGCTATAGCTGGACGATTAATGACTAAGCGTGGTAAAGGTAAAGCAGGATTTGCACACGTTCAGGACTTAGCTGGACA AATTCAAATTTACGTTCGTAAAGATCAAGTTGGCGATGACGAATTTGATTTATGGAAAAATGCTGATTTAGGCGATATCG TTGGTGTTGAAGGTGTAATGTTCAAAACAAATACTGGCGAATTATCGGTTAAAGCGAAGAAATTCACGCTACTAACTAAA TCATTGCGACCATTACCGGATAAATTCCACGGTTTACAGGATATTGAACAGAGATATCGTCAAAGATATTTAGATTTAAT TACGAACGAAGATAGCACTCGTACATTTATTAATCGTAGTAAAATCATTCAAGAAATGCGTAATTATTTAAATAATAAAG GTTTCTTGGAAGTAGAAACACCTATGATGCACCAAATTGCTGGTGGAGCAGCTGCTAGACCATTTGTAACACATCATAAT GCATTAGATGCAACGTTATACATGCGTATTGCTATTGAGTTGCATTTAAAACGTTTAATTGTCGGTGGACTTGAAAAAGT ATATGAAATTGGTAGAGTATTCCGTAATGAAGGTGTATCAACTAGACATAACCCTGAATTCACAATGATTGAATTATATG AAGCATATGCAGATTATCATGACATTATGGATTTAACAGAATCTATGGTGAGACATATTGCCAATGAAGTGTTAGGTTCT GCAAAAGTACAATACAATGGGGAAACGATTGATTTAGAATCTGCTTGGACTCGTTTGCATATTGTTGATGCTGTAAAAGA AGCTACTGGTGTAGATTTTTATGAAGTTAAAAGTGATGAAGAAGCTAAAGCTTTAGCTAAAGAACATGGTATTGAAATTA AAGATACAATGAAATATGGTCATATTTTAAATGAATTCTTTGAGCAAAAAGTTGAAGAAACACTTATTCAGCCAACGTTT ATCTATGGTCATCCGACTGAAATTTCACCTTTAGCGAAGAAAAATCCTGAAGATCCTAGATTTACTGATCGTTTCGAATT GTTCATTGTAGGTAGAGAGCATGCAAATGCATTTACTGAATTAAATGATCCTATTGATCAAAAAGGTCGTTTTGAAGCGC AACTTGTTGAAAAAGCGCAAGGTAATGATGAAGCGCATGAAATGGATGAAGATTACATTGAAGCGTTAGAATATGGTATG CCTCCGACAGGTGGTCTTGGTATCGGTATTGACAGATTGGTTATGTTATTAACTGACTCTCCATCAATCAGAGACGTATT ATTATTCCCTTATATGAGACAAAAATAA Protein sequence : MFECTSWNTKGLQQVKGEKVMSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSH VAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTK SLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHN ALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIANEVLGS AKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTF IYGHPTEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGM PPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 8e-120 | 50 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_001331513.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 5e-120 | 50 |
