Gene Information

Name : vraD (NWMN_2598)
Accession : YP_001333632.1
Strain : Staphylococcus aureus Newman
Genome accession: NC_009641
Putative virulence/resistance : Resistance
Product : ABC transporter ATP-binding protein, involved in vancomycin resistance
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 2865524 - 2866282 bp
Length : 759 bp
Strand : +
Note : -

DNA sequence :
ATGACGATATTATCAGTGCAACATGTTTCAAAAACATACGGTAAAAAGCACACATTTCAAGCACTTAAAGATATTAACTT
TGACATACAAAAAGGCGAATTCGTTGCGATTATGGGGCCTTCTGGATCAGGTAAGACAACCTTATTAAATGTACTAAGTT
CAATTGACCAAATTTCTAGCGGTAGCGTGATTGCTAACGGACAAGAGCTTAATAAACTTAATCAAAAAGCACTTGCCAAA
TTCCGCAAAGAATCATTAGGTTTCATCTTCCAAGATTACAGTATTCTGCCGACATTAACCGTTAAAGAAAACATTATGTT
ACCTTTATCTGTTCAAAAAATGTCGAAGGCAACAATGGAAGAAAATTATAAAGCGATCACGACAGCATTAGGTATTTATG
ACCTAGGAAATAAATACCCTAGCGAATTATCTGGTGGTCAACAACAAAGAACTGCAGCAGCGAGAGCATTTGTTCACAAA
CCACAAATCATATTTGCAGATGAGCCAACAGGCGCACTCGACTCGAAAAGTGCAAATGACCTATTACAACGTTTGGAAGA
AATGAATAAATCGTTTGATACAACTATTGTCATGGTTACACATGATCCGGTTGCAGCAAGTTTTGCAGAACGTGTCATCA
TGCTAAAAGATGGCCAAATTCATACACAACTTTATCAGGAAGGACGTTCTAAACAGGCCTTTTATGAAGACATTGTACAT
CTTCAATCAGTATTAGGTGGTGTCTCAAATGACATTTAA

Protein sequence :
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAK
FRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHK
PQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVH
LQSVLGGVSNDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 4e-30 45
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-32 45
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-32 45
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 5e-32 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vraD YP_001333632.1 ABC transporter ATP-binding protein, involved in vancomycin resistance CP001581.1.gene798.p Protein 1e-35 43
vraD YP_001333632.1 ABC transporter ATP-binding protein, involved in vancomycin resistance CP001581.1.gene598.p Protein 2e-37 43
vraD YP_001333632.1 ABC transporter ATP-binding protein, involved in vancomycin resistance NC_012469.1.7686878. Protein 4e-36 43