Gene Information

Name : guaA (Smed_3517)
Accession : YP_001329168.1
Strain : Sinorhizobium medicae WSM419
Genome accession: NC_009636
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3719416 - 3720978 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGACAGCCCATCCCGATACCGTCCTCATCGTCGATTTCGGCAGCCAGGTGACCCAGCTCATCGCCAGGCGCGT
GCGCGAATCCGGCGTCTATTGCGAGATCGTGCCGTTCCAGTCGGCCGAGGACGGTTTCCATCGCCTGAAGCCGAAGGCGG
TGATCCTGTCCGGCAGCCCGGCTTCGACGCTCGACGTCGGCTCGCCGCGTGCGCCTTCCGTCATTTTCGAAAGCGGCCTG
CCGGTCTTCGGCATCTGCTACGGTCAGCAGACCATGTGCGCGCAGCTCGGCGGCAAGGTCGAAAGCGGGCATCATCGTGA
ATTCGGCCGGGCTTTCCTCGAAGTCGAAAAGGACTGCCCGCTCTTCGAGGGGCTCTGGTCCCTCGGCTCGCGGCACCAGG
TGTGGATGTCGCATGGCGACCGGGTTACCGCCTTGCCCGATGGCTTCGAAGTCGTCGCCACCTCTTCCAACGCGCCCTTC
GCCTTCATCGCAGACGAGAAGCGCAGATACTATGCCGTCCAGTTCCATCCGGAAGTGGTGCATACGCCCGACGGGGCGAA
GCTCATCGCCAACTTCGTCCACAAGATCGCCGGCATCAAGGGCGATTGGACGATGTCGGCCTATCGCGCCAAGGCGGTCG
AAGCGATCCGCAACCAGGTCGGCGACAAGAAGGTGATCTGCGCGCTTTCCGGCGGCGTCGATTCGTCGGTTGCAGCACTC
CTCATCCACGAAGCCGTCGGCGACCAGCTCACCTGCATCCTCGTCGACCACGGTCTGATGCGCAAGGACGAGGCGGCGAA
CGTCGTCGCGATGTTCAAGGAGCACTACAACCTCCATCTGCTCCACGTCGACGCTTCCGACCGCTTCATTGGCGAACTCG
AAGGCGTCAGCGATCCGGAGACCAAGCGCAAGATCATCGGCCGCCTCTTCATCGAGGTCTTCGAGGAAGAGGCCGGGAAG
CTGGGCGGGGCAGATTTCCTCGCGCAGGGCACGCTTTATCCCGACGTCATCGAAAGCGTCTCCTTCACCGGCGGCCCTTC
GGTGACGATCAAATCGCACCACAATGTCGGCGGCCTGCCGGAGCGCATGAACATGCAGCTCGTCGAACCGCTGCGCGAAC
TCTTCAAGGACGAGGTACGCGTCCTCGGCCGCGAGCTCGGCCTGCCCGACAGCTTCATCGGCCGCCATCCCTTCCCCGGT
CCCGGCCTTGCGATCCGCTGCCCCGGCGGGATCAGCCGCGAGAAGCTCGAAATTCTGCGCGAGGCGGATGCGATCTATCT
TGACGAGATCCGCAAGGCAGGCCTCTACGACGCCATCTGGCAGGCCTTCGCCGTGCTGCTTCCCGTGCAGACGGTCGGCG
TCATGGGCGACGGGCGCACTTATGAATTCGTCTGCGCGCTTCGCGCCGTCACCTCCGTCGACGGCATGACGGCCGATTTC
TACCACTATGACATGGAATTCCTGGGCCGCGCTGCCACGCGCATCATCAACGAGGTCCGCGGCATCAACCGCGTCGTCTA
CGACGTCACCTCGAAGCCCCCGGGCACGATCGAGTGGGAATGA

Protein sequence :
MTQTAHPDTVLIVDFGSQVTQLIARRVRESGVYCEIVPFQSAEDGFHRLKPKAVILSGSPASTLDVGSPRAPSVIFESGL
PVFGICYGQQTMCAQLGGKVESGHHREFGRAFLEVEKDCPLFEGLWSLGSRHQVWMSHGDRVTALPDGFEVVATSSNAPF
AFIADEKRRYYAVQFHPEVVHTPDGAKLIANFVHKIAGIKGDWTMSAYRAKAVEAIRNQVGDKKVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKDEAANVVAMFKEHYNLHLLHVDASDRFIGELEGVSDPETKRKIIGRLFIEVFEEEAGK
LGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRVLGRELGLPDSFIGRHPFPG
PGLAIRCPGGISREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-137 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-115 49