Gene Information

Name : Smed_3427 (Smed_3427)
Accession : YP_001329080.1
Strain : Sinorhizobium medicae WSM419
Genome accession: NC_009636
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 3632689 - 3633441 bp
Length : 753 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAATCGTGAACAAGCGGGCAAAGCCCTCGTACTCATTCCGGCGCGCATGGCGTCGACGCGCCTGCCCGGCAAGCCGCT
TGCCGACATTTGCGGGCTGCCGATGATCGTGCAGGTGGCAAGGCGGGCGGCGGAGGCCGAGGTCGGCCGGATCGTGGTGG
CCGTGGATCATCCGGAGGTTTTCGCAGCCGTGAGCGACGCCGGCTTCGAGGCGATCATGACGCGGGTCGACCACCAGTCC
GGCTCCGACCGGATTCACGAGGCGCTTCTTAAGGCCGATCCGCAAGGTGAGGCGGAAATCGTCATCAACGTGCAGGGCGA
TTTGCCGACCATCGAGCCCGGCCCGATCCGTGCGGCACTGAAGCCGCTGGAAAATCCTTCGACGGACATTGCCACGCTGA
CCGTGGCGATCACCGACGAGCACGAAAAGACCAACCCCAACGTCGTCAAGGTCGTCGGCTCGCCGCTGTCGCAGAGCCGC
TTCCGCGCGCTCTATTTCACCCGCGCGACCGCGCCCTACGGCGAAGGTCCTCTCTATCACCATATCGGCCTTTACGCCTA
TCGCCGCAGGGCACTCGAGACCTTCGTTTCGTTGAAGCCGTCGGCGCTTGAAAAGCGCGAATCGCTGGAACAGCTGCGGG
CGCTCGAAGCGGGCATGCGCATCGATGTGGAGATCGTCGATTCGGTGCCGCTCGGCGTCGACACGCCTGCAGATCTCGAC
AAGGCCCGCCGGATCCTTTCGGCCCGGGCCTGA

Protein sequence :
MNREQAGKALVLIPARMASTRLPGKPLADICGLPMIVQVARRAAEAEVGRIVVAVDHPEVFAAVSDAGFEAIMTRVDHQS
GSDRIHEALLKADPQGEAEIVINVQGDLPTIEPGPIRAALKPLENPSTDIATLTVAITDEHEKTNPNVVKVVGSPLSQSR
FRALYFTRATAPYGEGPLYHHIGLYAYRRRALETFVSLKPSALEKRESLEQLRALEAGMRIDVEIVDSVPLGVDTPADLD
KARRILSARA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-29 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 5e-28 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-28 45