Gene Information

Name : Smed_2519 (Smed_2519)
Accession : YP_001328184.1
Strain : Sinorhizobium medicae WSM419
Genome accession: NC_009636
Putative virulence/resistance : Resistance
Product : Bcr/CflA subfamily drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 2616683 - 2617882 bp
Length : 1200 bp
Strand : +
Note : TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00744 putative transport protein transmembrane

DNA sequence :
ATGTCTTCAAAGCCACATGTCTGGCGCTATTCGCTGCCGGCAGCGCTGCTGCTGATGGCGCCCTTCGATATCCTCGCCTC
CCTGGCCATGGATATCTATCTCCCCATCGTTCCGGCGATGCCGGGCATTCTCGGGACCAGCCCCGCCGTGGTGCAGCTCA
CGCTGAGCCTCTATGTGGTCATGCTCGGCCTCGGCCAGATCGTCTTCGGGCCTCTCTCCGATCGCATCGGACGACGGCCC
GTGCTCATCGGCGGAGCGATGCTTTTCGCCGCGGCTTCGTTCTGCCTTGCGGCATCATCCAGCGCCATTCCTTTCGTCGC
CTTCCGCTTCCTGCAGGCGATTGGCGCATCTGCGGCCCTGGTGGCCACCTTCTCGACTATTCGGGATGTATATGGCAATC
GCCCTGAAAGCGTGGTCATCTACAGCCTGTTCAGTTCCATCCTGGCATTCGTGCCGGCTCTGGGGCCGATCGCCGGTGCC
GCGCTGGCGGAGAGGTTCGGATGGCGCTCGATCTTCGTGACACTGGGCGCATTTGCCGTAATCGCGCTGCTGCAGGCCTT
GCCCCGGTGGCATGAATCTCGCCCTTCGGCGCCCGCGCCGTCGCGGCACGCATTCGGGCCGCTTCTCCGCAGCCTCGCCT
TCTGGACCTATACTCTCGGCTTCAGCGCCGCCATGGGCACCTTCTTCGTGTTCTTTTCCACCTCACCGCGCGTGCTGATC
GGCAAGGCAGGATATTCGGAGCTTCAGTTCAGCCTCGCCTTTGCCACCGTCGCGGCCGTCATGATCTTCACGGCGCGCTT
TGCCAAGCAGTTTGTCTTCCGATGGGGAACTTCGGGCAGCCTCCTGCGGGGCATGTGCATGTTGCTCCTCGGGGCGGCAC
TCCTGGCTGCCGGGCAAGGCCTCGGCACCCCTTCGTCCTGGGTCTTCATCGCGCCCATGTGGGTCATGGCCGTCGGCATC
GTCTTCACGGTGTCGGTAACCGCGAACGGCGCTCTCAAGGATTTTGGAGACATGGCGGGTTCGGCGGTCGCAGTCTATTT
CTGCGTCCAAAGCCTCATCGTCGCGACGGCGGGGACACTGCTCGTGATCGCACTGCCCGGCGACACCGCATGGCCGCTTG
CGGCCTATGCCTCGATCATGGCCGGTATCGTGCTGATCGCGCGCCGGCAGCTGCATTCCGGAAGGCAGCCGCAGACATGA

Protein sequence :
MSSKPHVWRYSLPAALLLMAPFDILASLAMDIYLPIVPAMPGILGTSPAVVQLTLSLYVVMLGLGQIVFGPLSDRIGRRP
VLIGGAMLFAAASFCLAASSSAIPFVAFRFLQAIGASAALVATFSTIRDVYGNRPESVVIYSLFSSILAFVPALGPIAGA
ALAERFGWRSIFVTLGAFAVIALLQALPRWHESRPSAPAPSRHAFGPLLRSLAFWTYTLGFSAAMGTFFVFFSTSPRVLI
GKAGYSELQFSLAFATVAAVMIFTARFAKQFVFRWGTSGSLLRGMCMLLLGAALLAAGQGLGTPSSWVFIAPMWVMAVGI
VFTVSVTANGALKDFGDMAGSAVAVYFCVQSLIVATAGTLLVIALPGDTAWPLAAYASIMAGIVLIARRQLHSGRQPQT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 5e-98 68
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-99 65
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-99 65
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-99 65
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 1e-99 65
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 1e-99 65
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 7e-74 49
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 3e-73 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Smed_2519 YP_001328184.1 Bcr/CflA subfamily drug resistance transporter DQ984668.gene.p01 Protein 4e-74 49
Smed_2519 YP_001328184.1 Bcr/CflA subfamily drug resistance transporter AF156486.gene.p01 Protein 2e-72 49
Smed_2519 YP_001328184.1 Bcr/CflA subfamily drug resistance transporter DQ522237.1.gene4.p01 Protein 4e-74 49
Smed_2519 YP_001328184.1 Bcr/CflA subfamily drug resistance transporter NC_010410.6003586.p0 Protein 4e-74 49
Smed_2519 YP_001328184.1 Bcr/CflA subfamily drug resistance transporter AF294653.1.gene4.p01 Protein 6e-74 48