Gene Information

Name : Amet_4068 (Amet_4068)
Accession : YP_001321809.1
Strain : Alkaliphilus metalliredigens QYMF
Genome accession: NC_009633
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 4156252 - 4158012 bp
Length : 1761 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein, mobile region; Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; KEGG: tte:TTE1815 pyruvate kinase

DNA sequence :
ATGAAAAAAACAAAAATTGTCTGTACAATAGGGCCAGCCAGTGAATCTAAGGAAGTGTTCACTGAGTTAGTAAAGCAGGG
TTTAAACGTAGCTAGGTTAAACTTTTCCCATGGAAACCATGAAGAGCATGGTGAGCGAATTAAAATGATTAAAGAAGTGA
GACGAGAGCTTGAACAATCTGTAGCAATTTTACTAGATACTAAGGGACCAGAAATTCGCACAGGAAAGTTTAAAGATCCA
GAGGTCCTGCTAGCGGAAGGGCAGGTATTCACTGTGACCACACGTGATGTCGTAGGGGATCAAAATATGTGTAGTGTTAG
CTATGAAGGGTTGGCTAGAGATGTTAAGCCTGGAGATGAAATATTGATTGATGATGGACTAGTGGGACTTAGGGTGCAAA
AAATCATCCAAGGAACAGATGTTGAATGCATCGTTGAAAATGCAGGAATCGTGAAAAATCACAAAGGAGTCAATGTTCCA
GGGGTACAAATTAATTTACCTGCCATTACAGAAAAAGATGAAGGTGATATTGTATTTGGAATCCAGATGGATATTGATTT
TATTGCGGCTTCCTTCGTCAGAAAAGCATCTGATGTATTGGCTATCAAAAGGATATTAGAGGAAAATAATGCAGATCATA
TTCAAATTATCTCTAAAATAGAGAATCAAGAAGGAATGGATAATTTAGATGAAATCATAGAAGTCTCAGATGGGATTATG
GTAGCTCGAGGAGATTTAGGTGTAGAAATACCAACAGAAGATGTTCCCCTAGCTCAAAAAGAAATGATTCTAAAATGTAA
CAAGGTTGGAAAACCAGTGATCACAGCTACTCAGATGTTGGATTCTATGATGCGTAATCCTAGACCCACTCGTGCAGAGG
TAACGGATGTGGCCAATGCAATATTTGATGGAACCGATGCAATCATGCTTTCGGGGGAAACCGCAGCAGGAAAATATCCG
ATAGAATCTGTGAAAACAATGGCGAGAATCGCATTAAGAACTGAAGGGGCCATTGATTACCGTAGCCTATTGAACAAAAA
GGCCCAAGAACGGGAATTGACAATCACCGATGCAATTAGTCATGCTACCTGCAGTACAGCAAGTGACTTACAGGCATCTG
CAATTTTAATAGCTACGTCCTCAGGACATACCGCAAGGATGGTCTCTCGATTTAAACCTCAGGCACCAATTATTGCAGCC
ACAACCAGTGAGCGTGTGATGAGAAAGCTGAGTTTAACTTGGGGTGCTTATTGTCTATTAGTAGATGAATTTCAATCAAC
CGATGATATTATTGATGCAACAGTGGAACATGCCTTGGAGAAAGAGTATATTAAGAGAGGCGACTTGATCGTTATGACGG
CAGGAGTGCCTGTAGGCATAGCAGGAACAACAAACCTATTGAAGGTACATATTGTTGGGGATGTATTGGTAAATGGAACC
GGGGTAGGCAAAATTCCCGCCACTGGAAAAGTGGTTGTGATCCATCAGCATGATGAGCTAGGACAAGAAACATTCAATGA
GGGTGACATTTTAGTGGTTTCTTGTACAGATAAGGATCTGATTCCATTGATGGAGAAAGCAGGGGCTATGATTGTAGAAG
AAGGTGGCATCACAAGTCATGCAGCTATTGTAGGGTTAAACCTTCATAAGCCCACAGTGGTTGGAGCCATAGGCGCAACA
GAGAAGCTGAAAACCGGAGATATTGTCACTGTAGATACCATTCGGGGATTGATATATAGTGGAAAGACACGTGTCTTGTA
A

Protein sequence :
MKKTKIVCTIGPASESKEVFTELVKQGLNVARLNFSHGNHEEHGERIKMIKEVRRELEQSVAILLDTKGPEIRTGKFKDP
EVLLAEGQVFTVTTRDVVGDQNMCSVSYEGLARDVKPGDEILIDDGLVGLRVQKIIQGTDVECIVENAGIVKNHKGVNVP
GVQINLPAITEKDEGDIVFGIQMDIDFIAASFVRKASDVLAIKRILEENNADHIQIISKIENQEGMDNLDEIIEVSDGIM
VARGDLGVEIPTEDVPLAQKEMILKCNKVGKPVITATQMLDSMMRNPRPTRAEVTDVANAIFDGTDAIMLSGETAAGKYP
IESVKTMARIALRTEGAIDYRSLLNKKAQERELTITDAISHATCSTASDLQASAILIATSSGHTARMVSRFKPQAPIIAA
TTSERVMRKLSLTWGAYCLLVDEFQSTDDIIDATVEHALEKEYIKRGDLIVMTAGVPVGIAGTTNLLKVHIVGDVLVNGT
GVGKIPATGKVVVIHQHDELGQETFNEGDILVVSCTDKDLIPLMEKAGAMIVEEGGITSHAAIVGLNLHKPTVVGAIGAT
EKLKTGDIVTVDTIRGLIYSGKTRVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-106 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-107 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-107 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-106 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amet_4068 YP_001321809.1 pyruvate kinase VFG0479 Protein 3e-107 52