Gene Information

Name : Amet_3707 (Amet_3707)
Accession : YP_001321486.1
Strain : Alkaliphilus metalliredigens QYMF
Genome accession: NC_009633
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3805534 - 3806691 bp
Length : 1158 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cth:Cthe_2799 cystathionine gamma-synthase

DNA sequence :
ATGAGTTGCGTGAAGGATAAGAAGTTGCATATTGAAACTGAAGTTGTACATGGATTTAAAGGATATGATCCCCATACGGG
AGCTGTAAGTTTTCCCATATACCAGAGTGCAACCTTTAGGCACCCGGGTCTTAATGAGACCACGGGCTATGATTACTCAA
GATTACAAAACCCGACCCGGGAAGAACTTGAAAATACCATGGCATGTTTAGAAAAAGGAAAGCATGGACTGGCTTTTTCC
AGTGGTATGGCGGCGATATCAACAGTGTTTACTCTGTTTACACCGGGTCAGCATATTATTGTTTCGGATGATCTTTATGG
AGGCACCTATCGAATTTGTGAAGAGATTTATAAACGGTATGGGATTGAATTTAGCTATGTTGACACCAGTAAAATTAGGG
AAGTTGAGAAGGCCTTAAGGGAGAACACAGCTGCGATATTCATTGAAACACCATCAAATCCCATGATGAAGGTAGCTGAT
ATTGCTTCAATTTCTGAAATTGCAAAGTCAAAGGAGGTAATGCTTATTGTAGACAATACCTTTTTGACACCGTATTTTCA
GAGACCCCTAGGGCTTGGGGCAGATATTGTGATTCATAGTGGAACAAAATATCTCGGTGGACACAATGATACCCTGGCTG
GATTTGTGATTGTAAAGGATGACGATCTAGGAGAAAACCTGAAACTGATTCAAAAAAGCCAAGGAGCTGTTCTAGCTCCC
TTTGATAGTTGGTTAATCCTACGTGGTATTAAAACATTAGGAATTAGACTTGAAAAGCAACAGCAGAATGCCATAAAAGT
AGCCGCTTGGTTAAAGGAGCACCAGCAGGTTGAAAAAGTCTATTATGTGGGAGATCCTGACCATGAGGGATACCAATTAT
CTAAGAAACAAGCATCGGGCTTTGGCGCCATGATTTCTTTTACAGTCAAGAGTCAGGAAGTGGCAAAGCAGGTACTTGAC
CGTGTTCAAGTCATAATGTTTGCAGAGAGTCTAGGTGGTGTTGAAAGTCTAATCACGTATCCTATGGTACAGACCCATGC
AGCTATCCCCCAAGAGATAAGGGAAAGAATTGGTGTAAATGATAAACTATTAAGGCTTTCTGTTGGCATAGAAGCAGTAG
AAGATATCATATTAGACTTAGAAAGGGCATTGAGGTGA

Protein sequence :
MSCVKDKKLHIETEVVHGFKGYDPHTGAVSFPIYQSATFRHPGLNETTGYDYSRLQNPTREELENTMACLEKGKHGLAFS
SGMAAISTVFTLFTPGQHIIVSDDLYGGTYRICEEIYKRYGIEFSYVDTSKIREVEKALRENTAAIFIETPSNPMMKVAD
IASISEIAKSKEVMLIVDNTFLTPYFQRPLGLGADIVIHSGTKYLGGHNDTLAGFVIVKDDDLGENLKLIQKSQGAVLAP
FDSWLILRGIKTLGIRLEKQQQNAIKVAAWLKEHQQVEKVYYVGDPDHEGYQLSKKQASGFGAMISFTVKSQEVAKQVLD
RVQVIMFAESLGGVESLITYPMVQTHAAIPQEIRERIGVNDKLLRLSVGIEAVEDIILDLERALR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-83 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-84 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-70 43