Gene Information

Name : Amet_3706 (Amet_3706)
Accession : YP_001321485.1
Strain : Alkaliphilus metalliredigens QYMF
Genome accession: NC_009633
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3804386 - 3805528 bp
Length : 1143 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cac:CAC0391 cystathionine beta-lyase

DNA sequence :
ATGAATTTTGGAACAAAACTAATACATAATACAAACGATAAGGATAAAATAACCGGTGCTTTAAGTATACCCATCTATCA
GGTGTCTACCTATCACCAAGAGGATATTGAGGCAGAACAGGAGTATCAATATTCAAGGTCAGAAAATCCAACAAGAAGAG
CCATAGAGGAAACAATAGCTGAACTTGAAAATGGAGATAGGGGGTTTGCGTTTTCCTCAGGAATGGCAGCGACTTCATCT
GTGCTTTCAATTTTTTCCGCAGGAGATCACATCATTGCCTGTCAAGACGTATATGGCGGAACATATAGGGCTTTGAATCG
TATTTTTAATCGGTACGGAATAGAAGTCAGCCTTGTAGATACAACTGATTTAGGTGAGATTGAGGCCAATATCAAAGAGA
ATACACGGGCAATTTTTCTTGAAACACCATCTAACCCTACATTGAAAATAACCAATCTTAAGGGTGCAGTGGGTATTGCA
AAGGCACATCATTTACTGGTTATTGTAGACAATACATTTATGACTCCTTATTTACAGCGCCCCCTTGATCTTGGAGCAGA
TATCGTGATCCATAGTGCAACGAAATTTATAGGTGGGCATAGTGATGTTGTTGCAGGTTTGGTTGCCGTAAAAGGGAAAG
CACTTTCGGAAAGACTGTACATGATTCAAAACGGTTTTGGGGCTGTGTTAGGACCACAGGATTCATGGTTGCTGCTGCGA
GGACTTAAAACTTTGAAGGTGAGGATGGATTATCAGCAAAAGAATGCTGAGGAGCTTGCTCAATGGTTATCCAATCATGA
AAAAATCCAGAAAGTATACTACCCTGGCCTGCTTGGGCACCAAAACCGAGAAATTCATGACACCCAGGCTAACGGTGCAG
GTGCAGTCATGAGCTTTAAGACAGTTGAAATAGAAACAGCACAGAAATTCATGAAAATGGTAAAACTTGCTGCTGTAGCA
GTAAGTCTCGGGGGAGTCGAAACAATTGCATCCTATCCCGTTAAAATGTCTCATGCAGCAATGCCTAAAGCCCAAAGAGA
ATCACTCGGTATTACTGAGAATTTGATTCGCCTATCAGTAGGGTTAGAGGACATAAAAGATTTGATAGAGGACTTTGATA
AAGCACTGGCGGGAGCGGAGTAA

Protein sequence :
MNFGTKLIHNTNDKDKITGALSIPIYQVSTYHQEDIEAEQEYQYSRSENPTRRAIEETIAELENGDRGFAFSSGMAATSS
VLSIFSAGDHIIACQDVYGGTYRALNRIFNRYGIEVSLVDTTDLGEIEANIKENTRAIFLETPSNPTLKITNLKGAVGIA
KAHHLLVIVDNTFMTPYLQRPLDLGADIVIHSATKFIGGHSDVVAGLVAVKGKALSERLYMIQNGFGAVLGPQDSWLLLR
GLKTLKVRMDYQQKNAEELAQWLSNHEKIQKVYYPGLLGHQNREIHDTQANGAGAVMSFKTVEIETAQKFMKMVKLAAVA
VSLGGVETIASYPVKMSHAAMPKAQRESLGITENLIRLSVGLEDIKDLIEDFDKALAGAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-85 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-87 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-75 48