Gene Information

Name : Amet_3125 (Amet_3125)
Accession : YP_001320923.1
Strain : Alkaliphilus metalliredigens QYMF
Genome accession: NC_009633
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 3168468 - 3171161 bp
Length : 2694 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGAACTTAAAACGTATGGTGATTATCGATGGGAACAGTCTCATTAACCGCGCTTTTTATGCACTACCACCTTTGACCAA
TAAAGAAGGCCAACATACCAATGCCATTTATGGCTTCATGACAATGCTGCTGAAGGTAATGGACGACTACGATCCACAGT
ATATTAGTGTGGCTTTTGACCGTAAAGCACCCACCTTTAGACATAAGAGCTTCGAAGGGTACAAGGCAGGCCGAAAAAAA
ATGCCTCCGGAATTAGCAGAGCAGCTAGAACCTCTAAAGGAAGTACTAGATGCATTTCATATTTACCGCGTTGAGATTGA
TGGATTTGAAGCCGACGACTTAATTGGTACCCTATCGAAATATGCCGAGGAACAAGACATTGAGTGTTTAATTGTAACGG
GTGATAAGGATGCGCTGCAGCTGGCTTCAGAAAAGGTGAAAATCCTTTTTACAAAAAAAGGGATTTCTAGCCTGGAGATA
TATGATCCCCAAAAGATTATGGAGCAATATGAAGTGACTCCTGAACAATTTATTGATCTAAAGGGACTGATGGGGGATAA
TTCTGATAACATTCCTGGAATTCCTGGTGTGGGGGAGAAAACGGCCATTAAATTGCTGAAGCAGTTTGGCACCGTAGAGA
ATTTAATTCAAAATGCGGGAGAAATTTCAGCGCAAAAACTTCGGGAGAAGGTAGAGAATAACACAGAGCAAGCCATGATG
AGTAAACGCTTAGCAACGATTATGACCAATGTACCTGTGGAAATTGAGCTAGAAAAACTAAAAAAGATCGCAATTGATGA
AGAAAAGGTATTAGCTCTCTTTAAAAAATTCGAGTTTAATACTTTGATTGGCAGAGTCATCGCTCGCAAAGAAGAGGTTG
ACGGTGAAGTAGTTGTTAAACAAGAAAAAATGACCAATGAGATTGCCCAAATTACCAATATAGATGAGCTTAAAAAGGCC
TTCGATGAAGTAAGAGCTGGCAAGCAGATGATACTCCAAACAAAAACAGAAGAAGAAAACATTGTACTAGATCATATCCT
AGCCATTACCTTTAGTGTTAATGGTGAAAAACTATATTACATAGATGTACGGGACTTTTCAGATAAAGAGGCTCTATTGA
TACAAATTAAAGAGGTATTAGAGGATGAGGAGATCCATAAAATTGGACACGACATTAAGCATGAAATTCGTCACTTTTAT
GTGCATGACATCGAAATGAAAAATGTCACATTTGATACCATGATAGGAGAATACTTGATTGATCCTGCTAAATCTAGCTA
TGCCCTAAAGGATTTAGCAGCCCAGTATATCGGGCAAGAGGTGATGTCAGAGGAAGAACTTAGAGGAAAGGGTAAAAATC
TAATATCCATTGGAGAAGCCCCTAAGGAAGACTTAATGAAATATCTGTGCCAGAGAGTCAGCGTTATTGGTAAAATCTAT
CCTGAAATTAAAGCCAAGATGCAAGAACTTGAATTAGAGAAACTGTACTACGAAGTGGAATTACCCTTGGTAGAGGTGTT
AGCTGCCATGGAATATAAGGGAATCAAAGTGGACCGAAGTATGTTAGAAATATTAGAAATAGAGTTTGGTGAACAAATCG
ATTTATTGACGAAGGCAATCCATGAACTGGCAGAAACGAATTTTAATATTAATTCTCCTAAGCAATTAGGCGAAGTGCTA
TTTGAAAAGTTGGAACTACCCCCAATAAAAAAGACAAAAACCGGTTATTCTACTAATGCAGAAGTGTTGGAAAAGTTACA
AGATCAACATGATATTATTCCTAAGATTTTAGAATATCGTCAAGTCACAAAACTAAAGAGTACCTATGTCGATGGATTAC
TAAATATTATTAATCCTGAGACAGGGCGTATTCATTCCAACTTCAATCAAACGGTTACAACAACAGGGCGAATCTCTAGT
ACAGAGCCTAATTTACAAAATATTCCTATCAAGCTAGAAATGGGTAGAAGACTCAGAAAGGTGTTTGTGGCTAATGAAAA
TCATCAGTTTATTGATGCAGACTACTCACAGGTTGAATTGAGAGTCTTAGCCCATATTTGTGAAGATGAGAATCTACTGG
ATGCCTTTCTTAAAAATCAGGATATCCATACAAGAACTGCAGCTGAAATTTTTGATGTACCCATGGAGGAAGTTACTGAC
TCCATGAGGAGCAGTGCCAAGGCCGTTAATTTTGGGATTGTCTATGGTATCAGTGATTATGGACTATCTCAAAATCTAAA
TATTACCAGAGTGAAAGCTAAAAAGTATATTGACAACTATTTGGATAAATATCCTTCGGTGAAAAGGTATATGGACGAGA
TTGTAGAGCAGGCTCACCAGCAGGGCTATGTTGTTACATTATTTAATAGAAGAAGATATCTTCCAGAGTTGAAATCCAGA
AATTTCAACATTAGATCCTTTGGTGAGCGAATGGCCATGAATACACCGATTCAAGGAAGTGCGGCTGATATTATTAAAAT
TGCCATGGTCAATGTGTATCGTAGGCTAAAGGAGCAGGGATTAACATCAAAATTAATTTTACAGGTACATGATGAATTAA
TTGTAGAGGCGCCAGACAATGAAGTAGAGGTAGCCATTAAAATAGTAAGAGAATCTATGGAAGAAGCAATGAATCTAAAG
GTACAGCTGAAAGTAGATTTAGCCTATGCCAATAATTGGTATGATGCGAAGTAA

Protein sequence :
MNLKRMVIIDGNSLINRAFYALPPLTNKEGQHTNAIYGFMTMLLKVMDDYDPQYISVAFDRKAPTFRHKSFEGYKAGRKK
MPPELAEQLEPLKEVLDAFHIYRVEIDGFEADDLIGTLSKYAEEQDIECLIVTGDKDALQLASEKVKILFTKKGISSLEI
YDPQKIMEQYEVTPEQFIDLKGLMGDNSDNIPGIPGVGEKTAIKLLKQFGTVENLIQNAGEISAQKLREKVENNTEQAMM
SKRLATIMTNVPVEIELEKLKKIAIDEEKVLALFKKFEFNTLIGRVIARKEEVDGEVVVKQEKMTNEIAQITNIDELKKA
FDEVRAGKQMILQTKTEEENIVLDHILAITFSVNGEKLYYIDVRDFSDKEALLIQIKEVLEDEEIHKIGHDIKHEIRHFY
VHDIEMKNVTFDTMIGEYLIDPAKSSYALKDLAAQYIGQEVMSEEELRGKGKNLISIGEAPKEDLMKYLCQRVSVIGKIY
PEIKAKMQELELEKLYYEVELPLVEVLAAMEYKGIKVDRSMLEILEIEFGEQIDLLTKAIHELAETNFNINSPKQLGEVL
FEKLELPPIKKTKTGYSTNAEVLEKLQDQHDIIPKILEYRQVTKLKSTYVDGLLNIINPETGRIHSNFNQTVTTTGRISS
TEPNLQNIPIKLEMGRRLRKVFVANENHQFIDADYSQVELRVLAHICEDENLLDAFLKNQDIHTRTAAEIFDVPMEEVTD
SMRSSAKAVNFGIVYGISDYGLSQNLNITRVKAKKYIDNYLDKYPSVKRYMDEIVEQAHQQGYVVTLFNRRRYLPELKSR
NFNIRSFGERMAMNTPIQGSAADIIKIAMVNVYRRLKEQGLTSKLILQVHDELIVEAPDNEVEVAIKIVRESMEEAMNLK
VQLKVDLAYANNWYDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 2e-148 41