Gene Information

Name : Amet_0277 (Amet_0277)
Accession : YP_001318169.1
Strain : Alkaliphilus metalliredigens QYMF
Genome accession: NC_009633
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 313292 - 315139 bp
Length : 1848 bp
Strand : +
Note : PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; CoA-binding domain protein; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-ter

DNA sequence :
ATGAAGAAAAGGGTGTTGAGTGGGCTATTGATGATGATGGATGCTGCCATGATAAACATTGCAGTGGTCATTGCCTTTTA
CATACGATTTGATGGGGCTTTTTCAGGTAGATTCGCAGGGCAGTATATTCCTATTTATACGGACAACTTATTAACTTTCA
CTTTGATTAAAATCGCACTTTTTTATGCCTTTGGTATGTATCAAAACCTATGGAAATATGCCAGCATAGAGGCAGTCTTT
CAAATTATGATCGCAGCCTTCGTTGCCAACACAGGTGTGGTTAGCTATATGGTCCTCACCCAACAGGGGCATCTACCTAG
GAGTATTTACCTGTTGATGTTTATTTTGGACATGTTACTGGTAGGGGGCATACGCTTTAGCTATCGTGCCACTCGGGGAC
TACGGGAGCATGGTTTCATTAGAAGGAAAAACTGTAAACGGGTGATGATTGTAGGAGCCGGGACTGCCGGGGCTGTGGTC
ATCAAAGAGCTTAAAATCCATGATAACTTAAATTACAAACCAGTGGCAGTCATCGATGATGATGAGTCAAAGTTAGGCTC
TAAAATCAATGGGGTTCCTGTCCTGGGGGATCGATATCATATTAAAAAGGTAGCTGAAATGAAACAAGTAGATGAAATCA
TTATTGCCATACCCTCTGGGTTTAGACAAGAACTCAAGGAAATCGTGGAGGAATGTAGTAAAACCAAGTGTAAACTAAAA
ATATTACCTGGCATTGGTGAGTTGATCGATGGCAAGGTCAGTATGAAAAAGGCCCGTGATGTGGAGATTGAAGATCTATT
AGGTAGGGATGCCATTAATATAGATCTTGAGGAGATCAGTGAGTATCTACATAATCAAGTGGTCTTAATTACTGGAGGTG
GAGGATCTATTGGGTCTGAGCTTTGCAGACAGATTGCCACATTCAATCCCAAGAAGCTCTTAATATTAGATAACTATGAA
AATAATGCTTATGATATACAAAATGAATTGAGAAGAAAATATCCTGAGTTGAATTTAGAAGTGTTGATTGCTTCAGTAAG
AGAAAGGGACCGTATAGAGGAAATTTTTGGTCAATATTTACCTGAGGTCATATTTCATGCGGCGGCCCATAAGCATGTTC
CTTTGATGGAGGCCAATCCTCAGGAAGCCATTAAAAATAATATTTTTGGAACCAAAAATGTAGCAGAATGTGCTGATCAA
TTTGGTGCCAAGAGATTTGTTCTAATTTCCACAGATAAAGCGGTGAATCCCACTAATATTATGGGTGCCACCAAGCGAGT
AGCAGAAATGTTGATCCAGTCTATTGATTTAACAAGTAAAACTGAGTTCGTGGCGGTACGGTTTGGAAATGTATTAGGGA
GCAATGGTAGTGTGATTCCCCTCTTTAAAAGGCAAATTGCAGAAGGGGGACCGGTGACGGTGACACATCCAGAGGTTACT
CGATACTTTATGACCATCCCTGAGGCAGTTCAGCTGGTGATCCAAGCTGGTTCAATGGCAAGTGGCGGGGAAATATTTGT
CTTGGATATGGGAGAGCCAGTGAAGATTATTGATTTAGCCAGAAACCTTATTCGCCTTTCTGGGATGGAGCCTGATGTGG
ATATGGACATTAAGGTGGTTGGGTTAAGGCCAGGAGAAAAGCTCTATGAAGAGCTATTGATGGATGAAGAAGGATTAGAG
TCAACCAAGCATGATAAGATTTTTGTGGGAAAACCATTCTTTACTGATTTAAAGTTTTTAGAAAGAGAGTTGGACATTTT
ATCGGATCTCTTATTATTAAGAGACCAAGAGGAAGTCAAAGAATATATGGTGAAGATTGTTCCTACATATCATAGAGAGA
CAAGCTGA

Protein sequence :
MKKRVLSGLLMMMDAAMINIAVVIAFYIRFDGAFSGRFAGQYIPIYTDNLLTFTLIKIALFYAFGMYQNLWKYASIEAVF
QIMIAAFVANTGVVSYMVLTQQGHLPRSIYLLMFILDMLLVGGIRFSYRATRGLREHGFIRRKNCKRVMIVGAGTAGAVV
IKELKIHDNLNYKPVAVIDDDESKLGSKINGVPVLGDRYHIKKVAEMKQVDEIIIAIPSGFRQELKEIVEECSKTKCKLK
ILPGIGELIDGKVSMKKARDVEIEDLLGRDAINIDLEEISEYLHNQVVLITGGGGSIGSELCRQIATFNPKKLLILDNYE
NNAYDIQNELRRKYPELNLEVLIASVRERDRIEEIFGQYLPEVIFHAAAHKHVPLMEANPQEAIKNNIFGTKNVAECADQ
FGAKRFVLISTDKAVNPTNIMGATKRVAEMLIQSIDLTSKTEFVAVRFGNVLGSNGSVIPLFKRQIAEGGPVTVTHPEVT
RYFMTIPEAVQLVIQAGSMASGGEIFVLDMGEPVKIIDLARNLIRLSGMEPDVDMDIKVVGLRPGEKLYEELLMDEEGLE
STKHDKIFVGKPFFTDLKFLERELDILSDLLLLRDQEEVKEYMVKIVPTYHRETS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-101 48
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 1e-103 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amet_0277 YP_001318169.1 polysaccharide biosynthesis protein CapD VFG1300 Protein 4e-106 46
Amet_0277 YP_001318169.1 polysaccharide biosynthesis protein CapD VFG0029 Protein 6e-87 43