Gene Information

Name : smpB (SaurJH1_0822)
Accession : YP_001315965.1
Strain : Staphylococcus aureus JH1
Genome accession: NC_009632
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 884941 - 885405 bp
Length : 465 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCTAAGAAGAAATCACCAGGTACATTAGCGGAAAATCGTAAAGCAAGACATGATTATAATATTGAAGATACGATTGA
AGCGGGAATCGTATTACAAGGTACAGAAATAAAATCGATTCGCCGAGGTAGTGCTAACCTTAAAGATAGTTACGCGCAAG
TTAAAAACGGTGAAATGTATTTGAATAATATGCATATAGCACCATACGAAGAAGGGAATCGTTTTAATCACGATCCTCTT
CGTTCTCGAAAATTATTATTGCATAAACGTGAAATCTTTAAATTAGGTGAACAAACTCGAGAAATTGGTTATTCGATTGT
GCCGTTAAAGCTTTATTTGAAGCATGGACATTGTAAAGTATTACTTGGTGTTGCACGAGGTAAGAAAAAATATGATAAAC
GTCAAGCTTTGAAAGAAAAAGCAGTCAAACGAGATGTTGCGCGCGATATGAAAGCCCGTTATTAA

Protein sequence :
MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPL
RSRKLLLHKREIFKLGEQTREIGYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-64 99
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 9e-31 50
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-24 44