Gene Information

Name : SaurJH1_0495 (SaurJH1_0495)
Accession : YP_001315640.1
Strain : Staphylococcus aureus JH1
Genome accession: NC_009632
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 515936 - 517078 bp
Length : 1143 bp
Strand : +
Note : PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sav:SAV0460 cystathionine gamma-synthase

DNA sequence :
ATGAATAAGAAAACTAAATTAATTCACGGTGGACACACAACGGACGACTATACAGGTGCAGTTACTACACCAATTTATCA
AACAAGTACATATTTACAAGATGATATTGGTGATTTACGTCAAGGATATGAATATTCTCGTACTGCGAATCCAACAAGAA
GTTCTGTAGAAAGCGTTATTGCGGCATTAGAAAATGGCAAACATGGCTTTGCGTTTAGTTCAGGTGTTGCAGCTATCAGT
GCAGTTGTTATGCTGTTGGACAAAGGTGATCATATTATTTTAAATTCAGATGTATACGGCGGTACTTATCGCGCATTGAC
AAAAGTATTTACACGATTTGGCATTGAAGTGGATTTTGTAGATACAACGCATACAGATTCAATTGTACAAGCGATACGCC
CAACAACAAAGATGTTGTTTATTGAAACACCTTCTAATCCATTATTACGTGTTACTGACATTAAAAAGTCTGCTGAAATT
GCGAAAGAACACGGTTTGATTTCAGTCGTTGATAACACATTTATGACACCTTATTATCAGAATCCATTAGATTTAGGCAT
CGATATTGTCTTGCATTCTGCAACGAAATATTTAGGTGGACATAGTGATGTCGTTGCTGGTTTAGTTGCAACATCGGATG
ACAAGCTTGCAGAACGTTTAGCATTTATTTCAAATTCAACAGGTGGCATTTTAGGACCTCAAGATAGCTATTTACTTGTG
AGGGGTATTAAAACATTAGGTTTACGTATGGAACAAATTAATCGCAGTGTTATTGAAATTATTAAAATGTTACAAGCACA
TCCAGCTGTGCAACAAGTGTTCCATCCAAGTATTGAAAGTCATTTAAATCATGATGTCCATATGGCTCAAGCGGATGGCC
ATACAGGTGTGATTGCATTTGAAGTGAAAAATACAGAAAGTGCCAAACAATTGATTAAAGCAACATCGTATTACACATTA
GCTGAAAGTTTAGGTGCAGTGGAAAGTTTAATTTCAGTACCTGCATTGATGACACATGCATCCATTCCAGCAGATATTCG
AGCTAAAGAAGGTATTACAGACGGACTTGTAAGAATTTCTGTAGGTATTGAAGATACTGAAGATTTAGTCGATGATTTAA
AACAAGCACTAGATACGCTATAA

Protein sequence :
MNKKTKLIHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLRQGYEYSRTANPTRSSVESVIAALENGKHGFAFSSGVAAIS
AVVMLLDKGDHIILNSDVYGGTYRALTKVFTRFGIEVDFVDTTHTDSIVQAIRPTTKMLFIETPSNPLLRVTDIKKSAEI
AKEHGLISVVDNTFMTPYYQNPLDLGIDIVLHSATKYLGGHSDVVAGLVATSDDKLAERLAFISNSTGGILGPQDSYLLV
RGIKTLGLRMEQINRSVIEIIKMLQAHPAVQQVFHPSIESHLNHDVHMAQADGHTGVIAFEVKNTESAKQLIKATSYYTL
AESLGAVESLISVPALMTHASIPADIRAKEGITDGLVRISVGIEDTEDLVDDLKQALDTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-177 99
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-178 99
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-78 44