Gene Information

Name : SaurJH1_2494 (SaurJH1_2494)
Accession : YP_001317605.1
Strain : Staphylococcus aureus JH1
Genome accession: NC_009632
Putative virulence/resistance : Virulence
Product : beta-channel forming cytolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2580737 - 2581684 bp
Length : 948 bp
Strand : +
Note : TIGRFAM: beta-channel forming cytolysin; PFAM: Combined Leucocidin/ASH4 hemolysin; KEGG: sam:MW2343 gamma-hemolysin component C

DNA sequence :
ATGCTTAAAAATAAAATATTAGCTACAACTTTATCTGTGAGCTTACTTGCCCCTCTTGCCAATCCGTTATTAGAAAATGC
TAAAGCTGCCAACGATACTGAAGACATCGGTAAAGGAAGCGATATAGAAATTATCAAAAGGACAGAAGATAAAACAAGTA
ATAAATGGGGCGTGACTCAAAATATTCAATTTGATTTTGTGAAGGATAAAAAATATAACAAAGATGCTCTGATATTAAAG
ATGCAAGGATTCATTAGCTCTAGAACAACATATTACAACTATAAAAAAACTAATCATGTTAAAGCTATGCGATGGCCATT
CCAATATAATATTGGTTTAAAAACAAATGATAAATATGTTTCTTTAATTAATTATTTACCTAAAAATAAAATTGAATCTA
CAAACGTGAGTCAGACATTAGGATACAATATCGGTGGTAATTTCCAATCAGCCCCATCACTCGGTGGTAATGGATCATTT
AACTATTCTAAATCGATTAGCTATACACAACAAAATTATGTAAGTGAAGTAGAACAACAAAACTCAAAAAGTGTTTTATG
GGGCGTCAAAGCGAATTCATTCGCCACTGAATCAGGTCAAAAATCAGCATTTGATAGCGATTTATTTGTAGGCTACAAAC
CTCATAGTAAAGATCCTAGAGATTATTTCGTTCCAGACAGTGAGTTACCTCCTCTTGTACAAAGTGGATTTAACCCTTCA
TTTATCGCCACAGTATCTCATGAAAAAGGTTCAAGCGATACAAGCGAATTTGAAATTACTTACGGAAGAAACATGGATGT
CACTCATGCCATTAAAAGATCAACGCATTATGGCAACAGTTATTTAGACGGACATAGAGTCCATAATGCATTCGTAAATA
GAAACTATACTGTTAAATACGAGGTCAATTGGAAGACTCATGAAATCAAGGTGAAAGGACAGAATTGA

Protein sequence :
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILK
MQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSF
NYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPS
FIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 3e-113 77
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 3e-113 77
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 4e-88 68
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 4e-88 68
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 4e-88 68
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 3e-88 68
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 7e-86 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SaurJH1_2494 YP_001317605.1 beta-channel forming cytolysin VFG1274 Protein 5e-134 100
SaurJH1_2494 YP_001317605.1 beta-channel forming cytolysin VFG1277 Protein 1e-113 77
SaurJH1_2494 YP_001317605.1 beta-channel forming cytolysin VFG1273 Protein 5e-88 68