Gene Information

Name : SaurJH1_1905 (SaurJH1_1905)
Accession : YP_001317029.1
Strain : Staphylococcus aureus JH1
Genome accession: NC_009632
Putative virulence/resistance : Virulence
Product : beta-channel forming cytolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1992353 - 1993288 bp
Length : 936 bp
Strand : -
Note : TIGRFAM: beta-channel forming cytolysin; PFAM: Combined Leucocidin/ASH4 hemolysin; KEGG: saa:SAUSA300_1769 leukotoxin LukE

DNA sequence :
ATGTTTAAGAAAAAAATGTTAGCTGCAACTTTGTCAGTAGGACTGATTGCGCCTTTAGCATCTCCGATTCAAGAATCTAG
AGCTAATACTAATATAGAGAATATTGGTGATGGTGCTGAAGTAATCAAACGTACGGAGGATGTAAGTAGTAAGAAATGGG
GCGTTACTCAAAATGTTCAATTCGACTTTGTAAAAGATAAAAAATATAACAAAGATGCTTTAATTGTTAAAATGCAAGGT
TTTATTAATTCCAGAACTTCATTTTCAGATGTGAAGGGTAGTGGATATGAATTGACTAAACGAATGATTTGGCCATTCCA
ATATAATATAGGACTGACGACTAAAGATCCAAATGTTAGCTTAATCAATTACCTTCCTAAAAACAAAATAGAAACTACTG
ATGTTGGTCAAACATTAGGATATAACATTGGAGGTAATTTCCAGTCAGCACCATCTATAGGTGGCAATGGCTCATTTAAT
TATTCTAAAACAATTAGTTATACCCAAAAGAGTTATGTCAGTGAAGTAGACAAGCAAAACTCAAAATCAGTTAAATGGGG
TGCTAAAGCAAACGAATTTGTTACGCCTGATGGTAAAAAATCTGCGCATGATAGATATTTATTCGTACAAAGTCCAAATG
GTCCAACAGGTTCAGCAAGAGAATATTTTGCTCCTGATAATCAATTGCCACCTTTAGTTCAAAGTGGCTTTAATCCATCA
TTTATCACTACACTATCACATGAAAAAGGTTCAAGTGATACGAGTGAATTTGAAATTTCATATGGTAGAAACTTAGATAT
TACATATGCGACTTTATTCCCTAGAACTGGTATTTACGCAGAAAGAAAGCATAATGCATTTGTAAATAGAAACTTTGTAG
TTAGATATGAAGTTAATTGGAAAACACACGAAATTAAAGTGAAAGGACATAATTAA

Protein sequence :
MFKKKMLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQFDFVKDKKYNKDALIVKMQG
FINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVSLINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFN
YSKTISYTQKSYVSEVDKQNSKSVKWGAKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPS
FITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNWKTHEIKVKGHN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 4e-142 99
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 4e-142 99
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 4e-142 99
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 4e-142 99
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 4e-142 99
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 4e-142 99
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 4e-142 99
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 2e-109 74
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 1e-100 69
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 1e-100 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SaurJH1_1905 YP_001317029.1 beta-channel forming cytolysin VFG1273 Protein 6e-106 71
SaurJH1_1905 YP_001317029.1 beta-channel forming cytolysin VFG1277 Protein 6e-101 69
SaurJH1_1905 YP_001317029.1 beta-channel forming cytolysin VFG1274 Protein 3e-90 67