Gene Information

Name : Smed_4174 (Smed_4174)
Accession : YP_001312912.1
Strain :
Genome accession: NC_009620
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 647437 - 649269 bp
Length : 1833 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATCTATTCAAGCCTCTCGGCGCGACCCCTTCGGTCACCCAAGGGCCGCTCCCCGCGTCCCAAAAGGTCTACAGGCC
GGGCGATATCCATCCCGACATCCGCGTGCCGATGCGCGAGATCACCCTGCATCCGACCTCGGGCGAACCGCCGGTGACCG
TATACGACGCCTCCGGACCCTACACGCTTGAGAATGCCGATATCCGCATCGACGCAGGACTGCCGCGTCTGCGCCACGAC
TGGATCCTGAAGCGCGGCGGCGTGGAAAGTTACGAGGGCCGAGCGGTCAAGGCGGAAGACAACGGCTTTGCGAGCGGCGA
GCGCCTCACGCCGGAATTCCCGGTGCGCAATCAGCCGCTTCGCGCCAAGCCGGGACAAGCGGTCACCCAGATCGCCTTTG
CCCGCGCCGGCATCATCACACCGGAAATGGAGTTCATCGCCATCCGCGAAAATCTCGGCCGCAAAGCCGCGAAGGAGGTA
CTCACGCGCGATGGCGAGAGCTTCGGCGCATCGGTCCCCGATTTCGTCACGCCGGAATTCGTCCGCCAGGAGGTGGCCGC
CGGCCGGGCCATCATTCCGGCCAACATCAACCATCCGGAGTCGGAGCCGATGATCATCGGCCGCAACTTTCTGGTGAAGA
TCAACGCGAATATCGGCAATTCCGCCGTGACTTCCTCGATGGCCGAGGAAGTCGAGAAGATGGTATGGGCGACCCGCTGG
GGCGCCGATACGGTCATGGACCTTTCCACCGGCCGCAACATCCACAATATCCGCGAATGGATCATCCGCAATTCGCCGGT
GCCGATCGGCACGGTACCGCTTTACCAGGCACTGGAAAAGGTGAACGGCATTGCCGAGGACCTTTCCTGGGAGGTCTTCC
GCGACACGCTAATCGAACAGGCGGAACAGGGCGTAGACTATTTCACCATTCATGCCGGCGTCAGGCTCCACTATATCCCG
CTCACCGTCGATCGAGTCACCGGCATCGTCTCGCGCGGCGGATCGATCATGGCCAAGTGGTGTCTGCATCACCACCAGGA
GAGCTTCCTCTACGAGCATTTCGAGGAGATCTGCGACATCTGCCGCGCCTATGACGTTTCCTTTTCGCTGGGCGACGGTC
TGCGGCCCGGTTCTATCGCCGACGCCAACGACCGGGCGCAGTTCGCCGAACTCGAAACGCTCGGCGAGTTGACGCAGATC
GCCTGGGCCAGGGATTGCCAGGTGATGATCGAAGGCCCCGGCCACGTGCCGATGCACAAGATCAAGGAGAACATGGACAA
GCAGCTTGCCGTTTGCGGCGAAGCGCCTTTCTACACGCTGGGGCCGCTGACCACCGATATCGCGCCGGGCTACGACCACA
TCACCTCCGGCATCGGCGCGGCGATGATCGGCTGGTTCGGCACCGCGATGCTCTGCTACGTGACGCCGAAGGAGCATCTG
GGCCTTCCCGACCGCAACGACGTCAAGATGGGCGTCATCACCTACAAGATCGCCGCGCATGCCGCCGATCTCGCCAAGGG
GCATCCGGCCGCGCGCATCCGTGACGATGCACTGTCGCGCGCGCGCTTCGAGTTCCGCTGGGAGGATCAGTTCAATCTCT
CGCTCGACCCGGAGACGGCGCGGAACTTCCATGACGAAACGCTGCCGAAGGAGGCGCACAAGGTCGCGCATTTCTGCTCC
ATGTGCGGTCCGAAATTCTGTTCGATGCGGATTTCCCACGACATCCGTGCCGAGGCGCAGAAGGAGGGCCTTGAGGCGAT
GGCAGCGAAATACCGCGACGGCGGCGATCTCTATATGCCGGTCGATGGGAGCGATGCGCCCACTGGAGAATGA

Protein sequence :
MNLFKPLGATPSVTQGPLPASQKVYRPGDIHPDIRVPMREITLHPTSGEPPVTVYDASGPYTLENADIRIDAGLPRLRHD
WILKRGGVESYEGRAVKAEDNGFASGERLTPEFPVRNQPLRAKPGQAVTQIAFARAGIITPEMEFIAIRENLGRKAAKEV
LTRDGESFGASVPDFVTPEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWATRW
GADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVNGIAEDLSWEVFRDTLIEQAEQGVDYFTIHAGVRLHYIP
LTVDRVTGIVSRGGSIMAKWCLHHHQESFLYEHFEEICDICRAYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTQI
AWARDCQVMIEGPGHVPMHKIKENMDKQLAVCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHL
GLPDRNDVKMGVITYKIAAHAADLAKGHPAARIRDDALSRARFEFRWEDQFNLSLDPETARNFHDETLPKEAHKVAHFCS
MCGPKFCSMRISHDIRAEAQKEGLEAMAAKYRDGGDLYMPVDGSDAPTGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 65