Gene Information

Name : smpB (Cbei_0634)
Accession : YP_001307777.1
Strain : Clostridium beijerinckii NCIMB 8052
Genome accession: NC_009617
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 756504 - 756974 bp
Length : 471 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAGAAAAAGAAATGAGAATTCATTAGCAGAAAATAGAAAAGCAAGGCATGACTATTTTGTAGAAGAGGCAATGGA
AGCAGGTTTGGTTTTAGTTGGGACAGAGGTTAAATCAATAAGAAATGGAAGAGTGAATCTTAAAGACTGTTATGCAGATA
TATATAATGGTGAAATATTTGTAAAGAATATGCACATATCTCCTTATGAACAAGGAAATATATTTAATGTAGATCCATTA
AGAGAGAGAAAATTACTTCTTCATAGAGATGAAATAAGAAGACTTGATGGTTTAGTGTCTAGAGATGGATATACCTTAAT
ACCTCTATCATTGTATTTGAAGGACGGAAAAGTTAAAGTTGCGCTTGGAGTTTGTAAAGGTAAGAAAAATTATGATAAGA
GAGACTCGATGTTAGAAAAAGCTCATAAGAGGGACATGGATAGAGCAATTAAGGAAAAGAATAAATATTAA

Protein sequence :
MARKRNENSLAENRKARHDYFVEEAMEAGLVLVGTEVKSIRNGRVNLKDCYADIYNGEIFVKNMHISPYEQGNIFNVDPL
RERKLLLHRDEIRRLDGLVSRDGYTLIPLSLYLKDGKVKVALGVCKGKKNYDKRDSMLEKAHKRDMDRAIKEKNKY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-39 61
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-27 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-28 45