Gene Information

Name : secA (Cbei_0433)
Accession : YP_001307577.1
Strain : Clostridium beijerinckii NCIMB 8052
Genome accession: NC_009617
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 523416 - 525983 bp
Length : 2568 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGGACTATTAAATGCCGTATTTGGAACATATAGTGAAAGAGAAGTTAAAAGGCTCAAACCTACTATACAAAAAATAAA
TGATCTAGATGAAGAGCTGCAAAAGCTTTCTGATGAGGAGTTAAAGGCAAAAACTCCAGCATTTAAAGAAAGATTAGCAA
ATGGTGAAACATTAGATGATATTTTACCAGAAGCATTCGCAGTTGTAAGAGAAGCTTCAAAAAGAGTTTTAGGAATGAAG
CACTATGATGAACAACTTATGGGTGGTATGATACTTCATCAAGGTAGAATATCAGAAATGAAAACAGGTGAAGGTAAAAC
TCTAGTTGCTACTTTACCAGCGTACTTAAATGGGTTAAGTGGAAATGGTGTTCACATAGTAACAGTTAACGACTATCTTG
CAAAAAGAGATGCTGAGCAGATGGGTGAGTTATATGGTTTCTTAGGATTAACTACAGGTGTTATTGTACATGAATTAAAT
AATGATCAAAGAAGAGAATCATATGCGTCAGATATCACTTATGGAACTAATAATGAATTTGGATTTGACTACTTAAGAGA
TAACATGGTTATTTACAAAGAGGAAAGAGTTCAAAGACCATTAAATTTTGCTATAGTCGATGAAGTTGACTCAATATTAA
TAGATGAAGCTAGAACTCCACTTATAATTTCGGGTCAAGGTGAAAAATCTACTGAATTTTATAAAGTTGCAGACTATTTT
GCAAAGAAGTTAGTTGTAGAGAAAGATTTTACTAGAGATGAAAAAGCAAATGCAGTAATGTTAACTGATGAAGGTGTTAG
AAAAGCAGAAGTAACCTTTAAAGTAGCCAATTATGCAGATGCTGAAAATATTGAATTACAACACTATGTAACTCAAGCGT
TAAAAGCAAACTTTGCCATGAGAAGAGACAAAGATTACATGGTTAAAGATGGCGAAGTAATAATTGTTGATGAATTTACA
GGAAGACTTATGGAGGGAAGAAGGTATTCAGATGGTCTTCATCAAGCGATAGAAGCTAAAGAAGGAGTTAAAATCGCTAG
AGAATCAAAAACTTTGGCTACTATAACATTCCAAAATTATTTTAGAATGTATAAAAAGTTATCAGGTATGACTGGTACTG
CATTAACAGAAGAAAATGAATTTAGAGAAATTTACGGGTTAGATGTTATTGTTATACCAACACATAGACCAATAGCAAGA
AAAGATAATCCAGACTTAGTATTTAGCACAGAGCTTGGAAAAATAAAGGCAGTTGCTTCAGAGGTTGAAAAAGCTCATGC
TAAAGGGCAACCAGTATTAGTTGGTACAGTAAGTATTGAAAAGTCAGAACTTGTATCAAGTATGCTTAAGAAAAAAGGAG
TACCACATCAAGTATTAAATGCTAAATTCCATGAACAAGAAGCTGAAATAATAAGTCATGCTGGTGAAAAGGGCATGGTT
ACTATAGCTACTAATATGGCAGGTAGAGGTACTGATATCAAGCTTGGCGAAGGTGTAGTTGAACTTGGCGGTCTTAAAAT
AATAGGTACTGAAAGACATGAATCAAGAAGAATAGATAACCAGTTAAGAGGACGTTCAGGAAGACAAGGAGATCCAGGTG
AATCAACATTCTTTATTTCCTTAGAAGATGATCTAATGAGAATATTTGGATCAGAAAAAATTCAAGGTGTTGTTGAAAAA
TTAGGACTTCAAGAAGAAGAAGCAATTGAAAGCAAAATGGTTTCAAAAGCTATTGAGAATGCTCAAAAGAAGGTTGAAGG
TAATAACTTCGATATTAGAAAACAATTATTGGGTTATGACGATGTAATGAATATCCAAAGAGAAGTTATCTACAAACAAA
GATCAGAAGTTCTTGAAGGCGAAGATGTAAAAGAAGAAATATTATCAATGACAAAGGATATTATTGCTGACGCTGTTAAT
ACTTATGTTACAGGTGAATCAGAAGATTATAGAGAAGAATTCTTGCATCTAATGGTTGCTTTACAAGATATATGTATAGC
GCCAGGTACAGTTAATTTACCTAGTCTTGAAAATCTGTCAAATGAGGAAATAATCGAAAGCTTATTTGAATCAGCACGTA
AGTTCTATGAACATAAGGAAGAAGAGTTTGGTGCAGAAAGATTAAGAGAAGTTGAAAGAGTTGTTCTTTTAAGAGCTGTT
GATACTAAATGGATGAATCATATAGATAATATGGATCATTTAAAACAAGGTATAGGGCTTCAATCATTCAAACAAATTGA
TCCAGTTCAAGCGTACCAAATGGAAGGTAGCGAAATGTTTAATGATATGATTAAAGCAATCAAAGAAGAAACAGTTAGAC
TGTTATTCCATGTTAGAATAGAAGTTGCACCAGAAAGAGTAAGGGTTGCTCAAGAAACTGCGGCAATTCATGAGGAATCT
TCAAGTGCCGCAGCTCCAGGGCCAGGACAAAATCAACCAGGTGGACCAGGTGGACCTAGTGCAGGGCCAGTAGCTCCAGT
TAGAAATCTAGATAAGCATGGAAGAAATGAATTATGCCCTTGTGGTAGCGGTAAGAAATTTAAAAATTGTTGTGGAAGAG
AAGCATAA

Protein sequence :
MGLLNAVFGTYSEREVKRLKPTIQKINDLDEELQKLSDEELKAKTPAFKERLANGETLDDILPEAFAVVREASKRVLGMK
HYDEQLMGGMILHQGRISEMKTGEGKTLVATLPAYLNGLSGNGVHIVTVNDYLAKRDAEQMGELYGFLGLTTGVIVHELN
NDQRRESYASDITYGTNNEFGFDYLRDNMVIYKEERVQRPLNFAIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
AKKLVVEKDFTRDEKANAVMLTDEGVRKAEVTFKVANYADAENIELQHYVTQALKANFAMRRDKDYMVKDGEVIIVDEFT
GRLMEGRRYSDGLHQAIEAKEGVKIARESKTLATITFQNYFRMYKKLSGMTGTALTEENEFREIYGLDVIVIPTHRPIAR
KDNPDLVFSTELGKIKAVASEVEKAHAKGQPVLVGTVSIEKSELVSSMLKKKGVPHQVLNAKFHEQEAEIISHAGEKGMV
TIATNMAGRGTDIKLGEGVVELGGLKIIGTERHESRRIDNQLRGRSGRQGDPGESTFFISLEDDLMRIFGSEKIQGVVEK
LGLQEEEAIESKMVSKAIENAQKKVEGNNFDIRKQLLGYDDVMNIQREVIYKQRSEVLEGEDVKEEILSMTKDIIADAVN
TYVTGESEDYREEFLHLMVALQDICIAPGTVNLPSLENLSNEEIIESLFESARKFYEHKEEEFGAERLREVERVVLLRAV
DTKWMNHIDNMDHLKQGIGLQSFKQIDPVQAYQMEGSEMFNDMIKAIKEETVRLLFHVRIEVAPERVRVAQETAAIHEES
SSAAAPGPGQNQPGGPGGPSAGPVAPVRNLDKHGRNELCPCGSGKKFKNCCGREA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 1e-123 41