Gene Information

Name : leuS (Cbei_4590)
Accession : YP_001311654.1
Strain : Clostridium beijerinckii NCIMB 8052
Genome accession: NC_009617
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 5316208 - 5318658 bp
Length : 2451 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCAAATTACGGAACAAAAATTGATGAAAAGTGGCAAAAATTTTGGGATGAGAATGAGGTTTATAAATTTAATCCTGA
AAATTCAGGTAAAAAACTCTATACATTAGAAATGTTTTCTTATCCATCAGGCGCTCAATTACATGCTGGTCACTGGTTTA
ACTATGGTCCAACAGATTCATGGGCAAGACTTAAGAGAATGCAAGGATATAATGTATTTCAACCAATGGGATTTGATGCC
TTTGGATTACCTGCTGAAAATTATGCTATAAAAACTGGAATTCATCCTCAAGATTCTACTTTAAAGAATATTGAGACAAT
GGAAAAACAATTGAAATCTATGGGTGCTATGTTTAATTGGGAAAATGAAGTTGTTACTTGTCTTCCTGATTATTATAAAT
GGACTCAGTGGCTATTCTTGAAACTTTACGAGAAAGGTCTAGCTTACAGAAAAAAAGCACCTGTAAATTGGTGCCCATCA
TGCAATACAGTATTAGCTAATGAACAAGTTGTTGATGGTGTTTGTGAAAGATGTAGTACTGAGGTTACAAAGAAAGACCT
TACTCAATGGTTCTTTAAAATAACTGAGTACGGCGATGAATTGCTTGATAAATTAGATGGTTTAGATTGGCCTGAAAAAA
CTAAGTCTATGCAAAAGCACTGGATTGGAAGATCTTATGGTGCAGAGGTTACTTTCAAAGTCAAGGATTCAGATTTGAAA
TTCGATGTATTTACTACAAGAGTTGATACTTTAAACGGTGTTACTTATGTAGTTTTAGCTCCTGAAAACAAACTAGTTGA
TGAGTTAACTATTCCAGAGTATAAGGCTGCTGTTGAAGAATATAAAGAAGCTGCTGCGAAGCAATCTGAAATTGAAAGAC
AATCAGTTTCAAAAGAAAAGACAGGAGTATTCACAGGATCTTATGCTATAAATCCTATTAATGGAAAAGTAGTCCCTATT
TGGATTTCTGATTATGTATTGGCTACTTATGGTACAGGATGTGTTATGGCAGTTCCTGCTCATGATGAAAGAGATTTTGC
TTTTGCAACAAAATTCAATTTACCAATCGAAAGAGTTATAACAGATAAAGAAAATACTAATCCAGACCTTCCATATTGCG
AATATGGAGTACTTGTTAATTCAGGAAAATTCGATGGATTAACAACTGATGAAGCTAAAAAGAAAATCGTTGAAGAATTA
GAAAAAGATGAATTAGGAGCAATGAAGAAAAACTTCAGATTAAGAGACTGGCTAGTTTCAAGACAAAGATATTGGGGTGC
TCCAATTCCTGTTATATACTGTGATGATTGTGGAATAGTTCCAGTACCTGAAAAGGATCTTCCAGTGAAACTTCCTTACA
ATGTTGAATTTACACCAGATGGTAAATCACCATTAGGTAAATGTGAGGATTTTGTAAATACAACTTGTCCTCATTGCGGG
AAGCCTGCAAAGAGAGAAGCTGATACTTTAGACACTTTTGTATGTTCATCTTTTTACTATTTAAGATATGTAGACAATAA
AAACGATGATGCACCTTTTGATTCTGAAAAAGTCAACAAAATGCTTCCTGTAGACAAATATGTTGGTGGACCAGAACATG
CTTGCATGCATTTATTATATGCTAGATTCATAACAAAAGCTTTAAGAGATATGGGATATTTAAACTTTGACGAACCATTC
TTAAGCTTAACTCACCAAGGATTGATCTTAGGACCAGATGGACTTAAAATGAGTAAATCAAAAGGAAATACTATTTCTCC
TGATGATTATATTAAAGAATATGGAGCTGACGTATTTAGAATGTACTTAATGTTTGGATTTGGTTATACTGAAGGTGGAG
CTTGGAGCGACGACGGAATAAAATCTGTTGGAAAATTCGTGGATAGAATTGAAAGAATCCTTGAAAATTGCAGAAATATA
ATAAATTCAAATGAGAGCACTAAAGATTCTATTGATTCAGCTGAAAAAGAATTAAACTTCTGGAAACATAATACTATTAA
AGGTGTTACTGAAGACGGAGATAAAATGCAATTTAACACTGCAATAGCAAGACTTATGGAGCTTACAAATGCTCTTAATA
AGTACACTCAAGAAAATATTAAAAACGCAAACTTCTTAAAAGAAACTATAGTTGATTTCATAAAACTACTTGCACCATTT
GCTCCTCACTTTGCTGAAGAGCAATGGAGTTTACTTGGAAATAATTCAACAATCTTTAATGAAAAATGGCCAGAATTTAA
CCCTGCTGCTTTAGTTAAAGATGAAGTCGAAATTGCAATCCAAATAAATGGTAAAATAAAAGCTAAAATCATGGTAGCTT
CTAATTTAGATGAAGAAGGTATAAAAGCTGCTTCATTAGAAAATGAGACTATTAAAGAAAATACTGAAGGTAAAACTATA
GTTAAAGTGATTGTAATTAAAGGAAGACTTGTTAATATAGTTGTAAAATAA

Protein sequence :
MANYGTKIDEKWQKFWDENEVYKFNPENSGKKLYTLEMFSYPSGAQLHAGHWFNYGPTDSWARLKRMQGYNVFQPMGFDA
FGLPAENYAIKTGIHPQDSTLKNIETMEKQLKSMGAMFNWENEVVTCLPDYYKWTQWLFLKLYEKGLAYRKKAPVNWCPS
CNTVLANEQVVDGVCERCSTEVTKKDLTQWFFKITEYGDELLDKLDGLDWPEKTKSMQKHWIGRSYGAEVTFKVKDSDLK
FDVFTTRVDTLNGVTYVVLAPENKLVDELTIPEYKAAVEEYKEAAAKQSEIERQSVSKEKTGVFTGSYAINPINGKVVPI
WISDYVLATYGTGCVMAVPAHDERDFAFATKFNLPIERVITDKENTNPDLPYCEYGVLVNSGKFDGLTTDEAKKKIVEEL
EKDELGAMKKNFRLRDWLVSRQRYWGAPIPVIYCDDCGIVPVPEKDLPVKLPYNVEFTPDGKSPLGKCEDFVNTTCPHCG
KPAKREADTLDTFVCSSFYYLRYVDNKNDDAPFDSEKVNKMLPVDKYVGGPEHACMHLLYARFITKALRDMGYLNFDEPF
LSLTHQGLILGPDGLKMSKSKGNTISPDDYIKEYGADVFRMYLMFGFGYTEGGAWSDDGIKSVGKFVDRIERILENCRNI
INSNESTKDSIDSAEKELNFWKHNTIKGVTEDGDKMQFNTAIARLMELTNALNKYTQENIKNANFLKETIVDFIKLLAPF
APHFAEEQWSLLGNNSTIFNEKWPEFNPAALVKDEVEIAIQINGKIKAKIMVASNLDEEGIKAASLENETIKENTEGKTI
VKVIVIKGRLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-165 45