Gene Information

Name : guaA (Cbei_0332)
Accession : YP_001307476.1
Strain : Clostridium beijerinckii NCIMB 8052
Genome accession: NC_009617
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 400819 - 402351 bp
Length : 1533 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAAGAGATTTAGTTTTAGTTGTTGATTTTGGTGGACAATATAACCAACTAATAGCAAGAAGAGTAAGAGAATGTGG
CGTTTATTGCGAGATTATTCCATATGACTATACTATAGAAAAGATAAAAGCTAAAAATCCAAAAGGTATAATATTTACAG
GCGGTCCTAACAGTGTTTATGGGGAAGATACTCCAACTGTAGAAAAAGAAGTATTTGAATTAGGCGTGCCAGTACTTGGA
ATATGCTATGGTGATCAACTAATGGCACATTTGCTAGGTGGAAAAGTTGCGACAGCACCAGTAAGAGAATATGGAAAAAC
AAATGTAAAAGTAGATAAATCATCTAAATTATTTGAAGGAATCGAAACTGATGGTATAGCTTGGATGAGTCATACTGATT
ATATTGAAGAAGCTCCAAAAGGATTTAAGGTAATAGCAACTACAGAAGTTTGTCCTGTTGCAGCTATGGAAAATGAAGAA
AAAAGGCTTTATGGAGTTCAATTCCATGCAGAAGTTGAACACACTCAATTTGGGCAAAAAATGCTAGAAAACTTTATACA
CAATATTTGTGGGTTAGAAAACAGCTGGTCTATGGGATCTTTTGCAGAAGAAAAAATAAAAGAAATAAAAGAATTAGTTG
GAGATAAGAAAGTGTTATGTGCTTTATCTGGTGGAGTTGACTCTTCAGTAGCAGCAATGATTGTACATAAGGCTATTGGT
CACAACTTAACTTGTATATTTGTTGACCATGGTTTACTAAGAAAAGATGAAGGCGATACTGTTGAAAGAGTGTTTAAGAA
AGAATTTGATATGAACATTAAGAGAGTTAATGTTGCAGATAGATTCCTTGGAAAACTTGCAGGAGTATCTGATCCTGAAA
CTAAGAGGAAAATAATCGGTGAAGAATTTATAAGAGTTTTTGAAGAAGAAGCTAAAAAGGTTGGTCAAATTGATTATCTT
GTTCAAGGAACAATTTATCCAGATATCGTAGAAAGTGGAACTAAGACATCGGCAACTATAAAATCCCATCATAATGTTGG
TGGACTTCCAGAAGATATGCAATTTGAACTTATAGAACCATTAAGAGAATTATTTAAAGATGAAGTTAGGGCAGTTGGAG
AGGAACTTGGCATTCCTCATAAATTGGTTTGGAGACAGCCTTTCCCAGGTCCAGGTCTTGCCATTAGAGTTTTAGGTGAG
ATTACAGAAGAAAAACTTGAAATAGTTAGAGAAGCAGATGCTATTTTCAGAGAAGAAATTGCAAATGCAAATCTTGATGA
ATCTATTTGGCAATACTTTGCATGTTTACCTAATATCCGTTCTGTTGGAGTTATGGGAGATGAAAGAACATATTCTCATA
CAATAGCTTTAAGAGCAGTTACATCAAGTGATGCAATGACTTCTGAATGGGCAAGAATTCCATACGAAATTTTAGATTTA
GTAAGCAGAAGAATTGTAAATGAAGTTAAGGGAGTAAACAGAATTGTTTATGACATAACTTCAAAACCACCAGCTACTAT
AGAATGGGAATAA

Protein sequence :
MKRDLVLVVDFGGQYNQLIARRVRECGVYCEIIPYDYTIEKIKAKNPKGIIFTGGPNSVYGEDTPTVEKEVFELGVPVLG
ICYGDQLMAHLLGGKVATAPVREYGKTNVKVDKSSKLFEGIETDGIAWMSHTDYIEEAPKGFKVIATTEVCPVAAMENEE
KRLYGVQFHAEVEHTQFGQKMLENFIHNICGLENSWSMGSFAEEKIKEIKELVGDKKVLCALSGGVDSSVAAMIVHKAIG
HNLTCIFVDHGLLRKDEGDTVERVFKKEFDMNIKRVNVADRFLGKLAGVSDPETKRKIIGEEFIRVFEEEAKKVGQIDYL
VQGTIYPDIVESGTKTSATIKSHHNVGGLPEDMQFELIEPLRELFKDEVRAVGEELGIPHKLVWRQPFPGPGLAIRVLGE
ITEEKLEIVREADAIFREEIANANLDESIWQYFACLPNIRSVGVMGDERTYSHTIALRAVTSSDAMTSEWARIPYEILDL
VSRRIVNEVKGVNRIVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-161 63
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-161 63
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-161 63
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-141 54