Gene Information

Name : Cbei_1506 (Cbei_1506)
Accession : YP_001308638.1
Strain : Clostridium beijerinckii NCIMB 8052
Genome accession: NC_009617
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 1777662 - 1778645 bp
Length : 984 bp
Strand : +
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: cac:CAC1543 lactate dehydrogenase

DNA sequence :
ATGAGAATTTTAGCATATAGTCATAGGCGTGATGAAACACAGTATTTCGAAGAATTTAGTAAAAAGTATAATGTTGAAGT
TGTTTTATGTAATGAGGAACCAAGTTTAGAAACAGCACCTCTTGCAAAAGGTTTTGATTGTATCAGTATAATTACAACAA
ATATAAACTCAGAATTAGTTGGAAAATTTCATGAGTTAGGTGTCAAATTTATATCAACAAGGACTATTGGATATGATCAT
ATAGATTTGAAAAAGGCTAAGGAACTTGGGGTTCGTGTAGGGAATGTGACGTATTCACCAAATAGCGTAGCAGATTATAC
TATAATGTTAATATTAATGGCAGTTAGAAAAGTCAAACTTATAATGGAAAGAAGCAATGTGCAAGACTTTTCTTTAAGGG
GTATTCAAGGTAAGGAATTACCTAACTTGACTATAGGTGTTGTAGGGACAGGGAAAATAGGGAGGACCGTTATCAAGCAT
TTAAGTGGTTTTGGTTGTAAGATATTAGCACATGATATATATGAAAATGATGAAGTGAAATCAAATGCTAAGTATGTAGA
TTTGGAAAATTTATTTAAATATAGTGATATTATAACATTGCATATGCCGGCTACAGATGATAATTATCATATAATTAATA
AGAAAGCCATTAAATTAATGAAAGATGGAGTCTTTATTATTAATACTGCCCGTGGATCATTAATTAATACAAATGATTTA
ATACATGGAATTGAAAGTAAAAAGATAGGAGGAGCTGCTTTAGATGTTATTGAACAGGAATCTAATATTTATTATAGTGA
TCTAAAGGGAGAGGCTTTAAAAAATAGAAATTTAGCTATTCTAAAGTCTTTTCCTAATGTAATAATAACACCTCATGCAG
CTTTTTATACAGATCAAGCGGTAAGTGATATGATTGAAAATTCAATAAAAAGCTGCATATTATTCTCAGAAAATAAGGAA
AACCCATGGGAGATAGATATATAA

Protein sequence :
MRILAYSHRRDETQYFEEFSKKYNVEVVLCNEEPSLETAPLAKGFDCISIITTNINSELVGKFHELGVKFISTRTIGYDH
IDLKKAKELGVRVGNVTYSPNSVADYTIMLILMAVRKVKLIMERSNVQDFSLRGIQGKELPNLTIGVVGTGKIGRTVIKH
LSGFGCKILAHDIYENDEVKSNAKYVDLENLFKYSDIITLHMPATDDNYHIINKKAIKLMKDGVFIINTARGSLINTNDL
IHGIESKKIGGAALDVIEQESNIYYSDLKGEALKNRNLAILKSFPNVIITPHAAFYTDQAVSDMIENSIKSCILFSENKE
NPWEIDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-65 45
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-64 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF155139.2.orf4.gene Protein 1e-64 46
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit NC_014475.1.orf2.gen Protein 9e-63 45
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit NC_005054.2598279.p0 Protein 9e-63 45
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF310956.2.orf4.gene Protein 1e-65 45
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit FJ349556.1.orf3.gene Protein 3e-63 45
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit U35369.1.gene5.p01 Protein 2e-64 43
Cbei_1506 YP_001308638.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF130997.1.orf3.gene Protein 2e-59 41