Gene Information

Name : Cbei_1449 (Cbei_1449)
Accession : YP_001308583.1
Strain : Clostridium beijerinckii NCIMB 8052
Genome accession: NC_009617
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1704794 - 1707223 bp
Length : 2430 bp
Strand : +
Note : TIGRFAM: ATPase P; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: dsy:DSY0829

DNA sequence :
ATGGCAAGCAATATAAAAATAGCTAGTGGTCCTGTTAACGCAAAATTATCAAAGAAAGATAGTATAAAGAAAGTAAAGAA
AGAATTTATCTTAGAAGGACTTGGATGTGCCAATTGTGCAGCTAAAATAGAACAAAAAATAAATGAATTAGATGGAGTTA
ATTTTGCCAATGTAAATTTTCTTACTAAAACTTTAATATTAGAAACAAATGAAGTTAATAAATTAGAAGAGCTGATAGGA
GCAGTAACTAACATTGTAACTAATATTGAATCTCATGTTAAAGTTGTAGAAAAGGTAACAGAAAAAATTTTGAAAAAAGA
AATTTTACTTGAAGGATTATGCTGTGGTAACTGTGCTGCAAAAATCGAAAGGGAATCAAATAATATAGATGGTGTGAAAT
CTGCACTAGTGGACTTTATATCAACAAAGCTTATTATAGAGATGGAAGACCCAGCAAAAGAAAATGCCATTATTGATAAT
GTTAAACGAATTGTCAAAAGAATAGAACCAGATGTTAATGTTGTTGAAATTGATGGAATAGATAGAAGAGCTATGAGCAA
GAATGAAAAGGTTGAAGAGGATAATGATAAGTTGGAAATTATAAGATTAGCTATTGGTGCTATAATTTTTGGAGCCGCTA
CTATTTTTAAATTTTCAAATTATATAGAATTATTATTATATCTAATAAGCTATATTCTTATAGGTGGAGAAGTGGTCTTA
AGAGCTCTAAAAAATATAGCTAAAGGTCAAGTATTTGATGAGAATTTCTTGATGACTATAGCAACTATTGGTGCTTTTGC
AATAGGCGAATATCCAGAAGGAGTTGCAGTTATGCTTTTCTACCAAATAGGAGAAATGTTTCAAGATATGGCTGTTAATC
GCTCTAGAAAATCCATCACATCACTTATGGATATAAGACCGGATTTTGCTAATTTAAAAATAAATAATGATTTCAAAAAA
GTAGATCCAGAAGAAGTTAAGCTTGGAGATATTATATTAGTTAAACCAGGCGAAAAAGTGCCATTAGATGGTGAAATAAT
TGAAGGAAACTCTATGGTTGATACTGCTGCATTGACAGGTGAGTCTGTTCCTAGAGAAGTAGGGGTAGGAGACAGTATTT
TAAGTGGAGTAATTAATAAAAATGGACTTTTAACAATAAAGGTAGAAAAAGAATTTGGAGATTCTACTGTTGCTAAGATA
CTGGATTTAGTTCAAAATGCAAGTGGAAAAAAGGCTCCGACAGAAAATTTTATAACAAAGTTTGCTAGATATTATACTCC
TGCTGTTGTTTTTGCAGCTTTAGCACTAGCTGTAATACCACCAATTGTTATTGAGGGAGCAACATTCTCACAGTGGATTT
ATAGAGCATTAGCATTCTTAGTTGTATCTTGTCCATGTGCATTAGTTGTATCTATACCTCTAGGATTTTTTGGAGGAATA
GGCGGAGCATCAAAAAATGGGATACTCGTTAAAGGTGGGAATTACCTTGAAGCATTAAATAATGTTGAAACAGTTGTGTT
TGATAAAACAGGAACTCTTACAAAAGGAATATTTAAAGTGACAGAAATAAGGCCAGAAAATAATATTTCAAAAGATGAAC
TCATAGCTTGTGCGGCTTATGCAGAAAATTACTCAAATCATCCAATAGCAACTTCTATATTAAGAGCTTATGATAAAGAG
ATAATTACAGATAAGATAACAGGTTATGAAGAAATATCAGGGCACGGCGTAAAAGTTGTTCTAGATGGAAAAGAGGTATT
TGCTGGAAACTACAAGTTAATGGATAAGGAGAATATATCTTATAACAAAGTAGATGAAATAGGAACTGTAGTCCATATTG
CTATAGAAAAGAAATATGCAGGTTATATTGTTATTTCAGATGAAGTAAAAGAAGATTCATTAAAGGCTATAAAAGCTTTA
AAAGAAATAGGTATTAAGAAGACAGTAATGCTTACAGGTGATAATAAAACTGTTGGAAGTAAAATTGCTAAAGAATTAGG
TTTGGATGAAGTTCATGCTGAACTATTACCAGATCAAAAAGTAGAAGAGCTAGAGCTATTGTTTAAGGAAAAATCACCTA
GAGGCAAGATAGTATTTGTTGGAGATGGAATAAATGATGCGCCAGTTCTAGCGAGGGCTGATATAGGTATAGCAATGGGC
GGTGTTGGCTCAGATGCAGCAATTGAAGCTGCTGATGTAGTTATAATGACAGATGAACCATCAAAAATAGCTTCGGCTAT
AAAGATTGCAAAGAAGACTAGAACTATAGTAATGCAAAATATAGTTTTCGCATTAGGTATTAAATTGATAATATTGGCGC
TTGTAGCTGTAGGTATGGGCACTATGTGGGAAGCGGTATTTGGTGATGTTGGAGTTGCATTGCTTGCAGTCTTAAATGCT
ATGAGAGCTATGAAAGTAGATAATATATAG

Protein sequence :
MASNIKIASGPVNAKLSKKDSIKKVKKEFILEGLGCANCAAKIEQKINELDGVNFANVNFLTKTLILETNEVNKLEELIG
AVTNIVTNIESHVKVVEKVTEKILKKEILLEGLCCGNCAAKIERESNNIDGVKSALVDFISTKLIIEMEDPAKENAIIDN
VKRIVKRIEPDVNVVEIDGIDRRAMSKNEKVEEDNDKLEIIRLAIGAIIFGAATIFKFSNYIELLLYLISYILIGGEVVL
RALKNIAKGQVFDENFLMTIATIGAFAIGEYPEGVAVMLFYQIGEMFQDMAVNRSRKSITSLMDIRPDFANLKINNDFKK
VDPEEVKLGDIILVKPGEKVPLDGEIIEGNSMVDTAALTGESVPREVGVGDSILSGVINKNGLLTIKVEKEFGDSTVAKI
LDLVQNASGKKAPTENFITKFARYYTPAVVFAALALAVIPPIVIEGATFSQWIYRALAFLVVSCPCALVVSIPLGFFGGI
GGASKNGILVKGGNYLEALNNVETVVFDKTGTLTKGIFKVTEIRPENNISKDELIACAAYAENYSNHPIATSILRAYDKE
IITDKITGYEEISGHGVKVVLDGKEVFAGNYKLMDKENISYNKVDEIGTVVHIAIEKKYAGYIVISDEVKEDSLKAIKAL
KEIGIKKTVMLTGDNKTVGSKIAKELGLDEVHAELLPDQKVEELELLFKEKSPRGKIVFVGDGINDAPVLARADIGIAMG
GVGSDAAIEAADVVIMTDEPSKIASAIKIAKKTRTIVMQNIVFALGIKLIILALVAVGMGTMWEAVFGDVGVALLAVLNA
MRAMKVDNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-94 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-94 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cbei_1449 YP_001308583.1 heavy metal translocating P-type ATPase BAC0055 Protein 5e-123 50