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Name : secA (Tmel_0589) Accession : YP_001305841.1 Strain : Thermosipho melanesiensis BI429 Genome accession: NC_009616 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 618619 - 621180 bp Length : 2562 bp Strand : - Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGAAATTATTCGACAAGAATGAGAGAGTTTTAAAAAGGTACTGGAAAAGGGTAAAAAAGATAAATGAAATTAACTTATC TAATGTGCCATTTAGTGAACTTATATTAAATATGGAAAAGATTAAAAACAATATAACAGGGGAAAACATAGATGATTACC TTGTAGATGTTTTTGCAATTGTTAGAGAGATTGCAAAAAGAACAATAGGATTAAGACCATTTGATGTGCAACTTATTGGT GGTATGGTGTTACATGAGGGAAAGGTAGCAGAAATGAAAACTGGTGAAGGAAAAACACTAGTAGCTACAATGCCAATTGT TTTAAATGCGTTGCTTAAAAAAGGTGTGCATCTTGTTACAGTAAATGATTATCTTGCTAAAAGAGATGCTATGTGGATGG GGCCTATTTATCTTGCTTTGGGACTTAGAGTAGCTGTTATAAATACCCAAAACAAATCTTATGAAGTTGTCTGGAAAAAT AAAGAACTTTTCGAGAAGGCAATTAGAGAAAATCTAAGTGTATGGCCAGAAGGTTTTGCTGAAGAATTTTTGCCTGATGA TAAAAAGGTAAATACAGATTGTTTTGATGTAGAATTAAAAGAAATTACTAGAAAAGAAGCATACGAATGCGATATTACAT ACGGGACAAATACAGAATTTGGATTCGATTATTTAAGAGATAACCTAGTGATTAATTTGGATTCTCGTGTTCAAAGAGGC CATTTTTTTGCGATTGTCGATGAAGTAGATAGTATACTTATTGATGAAGCTCGAACACCATTAGTAATAAGTGGGCCTTC TAAGACTAAAGCATCAGATTACAGAAGGTTCAACCAAGTTGCAAAGAGATTGAAAAAAGATGTCCATTTTACAGTGGATG AGAAGAAAAAGACAGTTGTTTTAACAGATGAAGGGATAGAGTATGTTGAAAAATTGCTGAACATAGAGAATCTTTACGAT CCAGAACATGTGAATAAAATGTATTTTCTTTTAAATGCACTTAAAGCTCATCATTTATTTAAAAAGGATGTTGACTACAT TGTCAACAATGGAGAAGTTATTATAGTTGACGAGTTTACTGGGAGATTGTTACCTGGTAGAAGGTACAGCGGAGGCCTCC ATCAGGCAATAGAAGCAAAAGAAGGTGTGCCAATAAAAGAAGAATCTTTAACATATGCAACTATAACCTATCAAAACTAT TTTAGAATGTATAAAAAATTGGCGGGAATGACTGGGACGGCAAAGACTGAGGAAGAAGAGTTTAAACAAATATATGGAAT GGAAGTAGTTGTAATTCCTACTCATAAACCTATGATTAGAAAAGATAGGGATGATTTAATATATAGAACAGAAGAGGAGA AATTCCAGGCAGTAGTAAGTGAAATAAAAAAAAGGCATGAGAAAGGTCAACCGGTGTTAGTTGGAACAACATCTATTGAG AAAAGTGAAAGATTAAGTCAAATGTTAAAAAAGGAAAATATACCGCATAACGTTCTTAATGCAAAGTATCATGAAAAAGA AGCGGAAATTGTTGCACGAGCTGGACAAAGGGGAGCTGTAACTATAGCAACGAATATGGCAGGTAGAGGTACTGATATAA AATTGGGGCCGGGTGTTAAAGAGCTTGGCGGGTTGTTAATAATAGGTACAGAAAGGCATGAAAGTAGAAGGATAGATAAT CAACTTAGGGGAAGAGCGGGTAGACAGGGTGATCCAGGAGAATCTATATTCTTTCTTTCTCTTGAGGATGATATAATTAG GATTTTTGGTGGAGAAAAGCTCGAAAAAATAATGAATTTGGTTAAAATTGAAAAAGGAGAACCTATTTATCATCCAATGC TCACAAAGCTCATTGAAAGGGTTCAGAAGAAAGTGGAAAGTATAAACTTTGCAATTAGAAAGAATTTATTACAAATGGAT ACAGTATTAGATGCTCAAAGAAAAGCTATTTACAGCTATAGAGAATATTTACTTTCTGGAAATCTAGACGAGCACTTTTA TGATGCAATGGAGGATTTCATAGAGAGGATATTGGAAGAATTTTGTGAAAAAGAAGTGTGTGATACTCAGAAGATAAACG AATCGTTGAAAATTTTGAATATAGACGAAAAATTACCGGATACAAGAGAAGAAACAAAAAAATATTTAAAAGATATTATA TTAAAGAGATATAATAAGAAGAAAGAAGAATTAGGTGAAGATTTTTCAAAAATAGGAAAATACATTGCTCTTAGAGTTTT GGATGAAAATTGGAGACAATATCTTGAAGAAGTTGAACATGTGAAAGAAGCAGTAAGCCTTAGAGCATATGGCCAAAAGG ATCCAATAATCGAGTTTAAAAAGGAAACATTTAGAATGTTTGATGAAATGATGGCAAGAATATATGAACAATCTATTGTG TATACCTTAAACATAAGAAAAATAACAGATGAAGCGGAAAAAGAATCTAAAAAGGAACTTGAAAAGTTATACGTACAACA CGATGAATTTAGTCTTGTTAACAGAAAAGAGAGAAGAACAGCAGAAAAGAAAGGGAAAAAAAGGTTAAAGGTTAAGAGGT GA Protein sequence : MKLFDKNERVLKRYWKRVKKINEINLSNVPFSELILNMEKIKNNITGENIDDYLVDVFAIVREIAKRTIGLRPFDVQLIG GMVLHEGKVAEMKTGEGKTLVATMPIVLNALLKKGVHLVTVNDYLAKRDAMWMGPIYLALGLRVAVINTQNKSYEVVWKN KELFEKAIRENLSVWPEGFAEEFLPDDKKVNTDCFDVELKEITRKEAYECDITYGTNTEFGFDYLRDNLVINLDSRVQRG HFFAIVDEVDSILIDEARTPLVISGPSKTKASDYRRFNQVAKRLKKDVHFTVDEKKKTVVLTDEGIEYVEKLLNIENLYD PEHVNKMYFLLNALKAHHLFKKDVDYIVNNGEVIIVDEFTGRLLPGRRYSGGLHQAIEAKEGVPIKEESLTYATITYQNY FRMYKKLAGMTGTAKTEEEEFKQIYGMEVVVIPTHKPMIRKDRDDLIYRTEEEKFQAVVSEIKKRHEKGQPVLVGTTSIE KSERLSQMLKKENIPHNVLNAKYHEKEAEIVARAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLLIIGTERHESRRIDN QLRGRAGRQGDPGESIFFLSLEDDIIRIFGGEKLEKIMNLVKIEKGEPIYHPMLTKLIERVQKKVESINFAIRKNLLQMD TVLDAQRKAIYSYREYLLSGNLDEHFYDAMEDFIERILEEFCEKEVCDTQKINESLKILNIDEKLPDTREETKKYLKDII LKRYNKKKEELGEDFSKIGKYIALRVLDENWRQYLEEVEHVKEAVSLRAYGQKDPIIEFKKETFRMFDEMMARIYEQSIV YTLNIRKITDEAEKESKKELEKLYVQHDEFSLVNRKERRTAEKKGKKRLKVKR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 1e-94 | 42 |
