Gene Information

Name : Tmel_0413 (Tmel_0413)
Accession : YP_001305666.1
Strain : Thermosipho melanesiensis BI429
Genome accession: NC_009616
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 435264 - 437633 bp
Length : 2370 bp
Strand : +
Note : PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase

DNA sequence :
ATGAGATATTTAGATGAAAAGATGCAAGAGTTAGTTCAGCAAGCAGCTGAAAATCTGGAGAACAAAAGGCAAAACCTTCT
AAAACCGGAACACGTATTATACGAAGTACTTCAAGAGGAAACCATTCAAAAAATTTTATTAAAAGATAAAGGATTAAGTT
TAGAAGAGATTTTTGATAGATTAGAAGAACTAATAGAAAGTCAATACGGGGTATACTATGGTTCCGGTTCAGGTGTTTAC
ATATCAAACGAGTTATCTAGAATTTTTGAACTTTCAAGAAAAGAAGCAAAATTATTAGGTTCAAACAAAGTTTCTCCTGT
ACATTTTCTTTTAGCACTGCTAAAAGACGGTTCCACACAAGCTGCATCAATACTATCTAGATATGGTATAACCTACGAAG
AGATAATTAAGAAAGTAAAAGAATTATCTGAAAGTGGTGAATTAGATGGAGAAGGAAACGTACTTACAAAATATACAGTT
GATTTAACTAAGCTTGCAAAAGAAGGAAAATTATCACCAGTTATTGGAAGAGAAAAAGAAATAGAAAGGGTTATAGAGAT
TCTCTCCAGAAAAACAAAAAACAACCCTGTATTAATTGGTGATCCCGGAGTTGGTAAAACTGCAATTGTGGAAGGTCTCG
CACAGAGAATTGTCGAAGGAAAAGTACCAGACAAATTAAAAAACAAACGTATTTTAATGCTTGACTTGGGTAAAATGCTT
GCAGGAAGTAAATATCGTGGTGAATTTGAAGAAAGACTTAAAAAGGTGATGGAAGAAATAAATAAATTAAAAAACAACGT
TATATTATTTATTGATGAACTTCATACAATTGTCGGAGCGGGTGCTGCTGAAGGTGCTATGGATGCATCAAATATGCTAA
AACCTGCACTTGCAAGAGGAGAATTACATGCAATAGGCGCAACAACATTGGAAGAATATAGAAAGCATATTGAAAAAGAC
AAAGCTCTTGCACGAAGATTCCAACCTGTCTTTGTAGAAGAGCCAAGTGTTGAAGAAACTATAAGAATATTAAAAGGTCT
AAAGGAAACTTACGAAAAACATCACAACGTAAAAATCACAGATGAAGCTATAGAAGCTGCAGCAAAATTATCTTCAAAGT
ACATACAAGATAGATTTATGCCAGATAAAGCAATAGATTTAATAGACGAAGCTGCAGCAAAAGTAAGTTTAAAGTCTTCC
GACCCAAAAATCTCTGAATTAAAAGAAAAGATAAAATCTTTAAGTGAAAAGATTGATGAATTAACCATCAATTCAAAATA
TAAAGAAGCAGCTGAAATGAAACAACAAATGTTCAAATTACAAAAGCAATACGAAGAGCTCGAAAAAAAATATGGTACAG
ATACCGTCTCCGCCGAAACTGTAGCAAAGGTTGTTGAATCTTGGACTGGAATTCCAGCAACAAAAATGATGGAATCTGAA
AAAGAAAAATTATTAAAGTTTGAAGAATTAGTTCACCAAAGAATGGTTGATCAAGAAGAAGCAGTAAGAGTTGTAGCAGA
TGCAATAAGAAAAGCAAGAGCAGGAATAAAAGATCCAAATAGACCTATCGGAACTTTCCTATTTTTGGGGCCAAGTGGTG
TCGGTAAAACAGAACTTGCAAAGACTATTGCAGAGTTGTTGTTTGGTTCAGAAAACGCATTAATTAGGATTGACATGAGT
GAGTATATGGAAAAACATTCAGTAGCAAGACTTATCGGTGCACCTCCAGGATACGTTGGATATGACCAAGGAGGGCAACT
TACTGAAGCTGTTAGAAGAAAACCATACAGTGTTATCTTGTTAGATGAAGTTGAAAAAGCACACCCTGAAGTTTTCAACG
TGTTATTACAAATGTTTGATGACGGAAGATTAACCGATGGAAAAGGAAATACTGTTGATTTCAGAAATACAATAATAATC
ATGACAAGCAATCTTGCAAGTGATAAAATCTTAAGAAAAGTAGAAGCAGGTATAGACTTTGAAAAGATAGAAGAAACGGT
AAGGGAAGATTTAAAACATTACTTTAGACCAGAGTTTATAAATAGAATAGACCACATTGTAATCTTTAAACCTCTAACTA
AGGAAAATATGAAAGAAATTGTCGAAAAATTAGTTGCAAAGCTTGAAAAAAGGTTAAAAGAAAAGAAGTTAAAGATAAGC
CTAACAGATACTGCAAAAGAATATCTAGCTAGCAAAGGATATGATCCTGCATTTGGTGCAAGACCTCTAAGAAGACTTAT
AGAAAGAGAAATCGAAACACCATTATCAAGAAAGATAATAGCAGGTGAAATAATCGAAGGTGATGTTGTTCTTGTTGACG
AAAAAGATGGAAAATTAATAGTTGAAAAAGAAAAACAGTTAACAAAATAA

Protein sequence :
MRYLDEKMQELVQQAAENLENKRQNLLKPEHVLYEVLQEETIQKILLKDKGLSLEEIFDRLEELIESQYGVYYGSGSGVY
ISNELSRIFELSRKEAKLLGSNKVSPVHFLLALLKDGSTQAASILSRYGITYEEIIKKVKELSESGELDGEGNVLTKYTV
DLTKLAKEGKLSPVIGREKEIERVIEILSRKTKNNPVLIGDPGVGKTAIVEGLAQRIVEGKVPDKLKNKRILMLDLGKML
AGSKYRGEFEERLKKVMEEINKLKNNVILFIDELHTIVGAGAAEGAMDASNMLKPALARGELHAIGATTLEEYRKHIEKD
KALARRFQPVFVEEPSVEETIRILKGLKETYEKHHNVKITDEAIEAAAKLSSKYIQDRFMPDKAIDLIDEAAAKVSLKSS
DPKISELKEKIKSLSEKIDELTINSKYKEAAEMKQQMFKLQKQYEELEKKYGTDTVSAETVAKVVESWTGIPATKMMESE
KEKLLKFEELVHQRMVDQEEAVRVVADAIRKARAGIKDPNRPIGTFLFLGPSGVGKTELAKTIAELLFGSENALIRIDMS
EYMEKHSVARLIGAPPGYVGYDQGGQLTEAVRRKPYSVILLDEVEKAHPEVFNVLLQMFDDGRLTDGKGNTVDFRNTIII
MTSNLASDKILRKVEAGIDFEKIEETVREDLKHYFRPEFINRIDHIVIFKPLTKENMKEIVEKLVAKLEKRLKEKKLKIS
LTDTAKEYLASKGYDPAFGARPLRRLIEREIETPLSRKIIAGEIIEGDVVLVDEKDGKLIVEKEKQLTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-159 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmel_0413 YP_001305666.1 ATPase VFG0079 Protein 9e-170 51
Tmel_0413 YP_001305666.1 ATPase VFG0080 Protein 1e-138 50