Gene Information

Name : Tmel_0253 (Tmel_0253)
Accession : YP_001305512.1
Strain : Thermosipho melanesiensis BI429
Genome accession: NC_009616
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 254814 - 256091 bp
Length : 1278 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATATAAAACTTCTTAGAAAAGAACCAGAAATTTTTTATAATGCACTTGAAAAAAGGGCAATGGATAAAGAAAT
TATTGATAGAATTTTAGTATTGGATAGAGAATGGAGAAGTATTTTGGCTGAGGTAAACAATTTAAAAGCGAAAAGAAACG
AGTTGTCAAAGATGGTTGCAAAATTAAAGGCTGAAAAAAAAGATATTGAAGCCGAAGAATTAATTAAAGAGAGTAAAGGA
ATTGGCGAGAAGATAAAAAAGTTGGACGAAAGGCAAAAAAGACTTGAAGAGGAAATGAAAAATCTTGCTTTGGAAATTCC
GAATATACCACATGAAAGTGTTCCAGTCGGTAAAGATGAAACGGAGAATGTTGAAGTTAGAAAATGGGGGACACCTAGAA
AATTTGATTTTGAACCAAAAGCACATTGGGATTTAGGACCAGAACTTGGGCTTATTGATTTTGAAAGGGCTGCCAAGTTA
AGTGGAGCTCGCTTTACTGTGATGTATGGACTTTTAGCAAAGCTTGAACGTGCACTTATTCAATTTATGTTGGATGTGCA
TACTAAGGAACATGGATATACTGAGGTGTGGGTTCCACATCTTGTTAGAAGAGAGGTTATGATATGGACAGGAAAGCTTC
CAAAATTTGAAGATGAATCATACAATACGAAAAAAGATGATCTTTTCTTAATTCCCACTGCTGAAGTGCCCATTACCGCA
TTACATGCAGAAGAAATATTGAAGGAAAAAGAACTTCCAAAAAAATACGTTTCGTATACTTCTTGTTATAGAAGAGAAGC
GGGAAGCTATGGAAAAGATGTCAGAGGAATGATAAGGCAGCATCAATTTGATAAAGTTGAATTGGTGTGGTTTACAAAGG
AAGAAGAATCTTTTAATGCATTGGAGCAACTAACTAGAGATGCGGAGAGGATATTACAACTTTTGGAGTTACCGTACAGG
GTGGTAAATCTTTGTACAGGTGATTTGGGCTTTGCATCTGCAAAGACTTACGATATTGAAGTTTGGCTTCCTTCATATAA
TGATTATAAAGAAGTTTCGTCGTGTAGTAATATTACCGATTTTCAAGCAAGAAGAGCAAATATTAAATATAGAGGTTCCG
ACAATAAAACGCATTTTGTTCACACGTTGAACGGTTCTGGATTGGCTATTGGTAGAACACTTGTTGCAATTATGGAAAAT
TATCAAAATGAAGATGGTACAATCACTATTCCTAAGGTATTAGTTCCATATATGGGAGTGGAAAAAATATCCATTTGA

Protein sequence :
MIDIKLLRKEPEIFYNALEKRAMDKEIIDRILVLDREWRSILAEVNNLKAKRNELSKMVAKLKAEKKDIEAEELIKESKG
IGEKIKKLDERQKRLEEEMKNLALEIPNIPHESVPVGKDETENVEVRKWGTPRKFDFEPKAHWDLGPELGLIDFERAAKL
SGARFTVMYGLLAKLERALIQFMLDVHTKEHGYTEVWVPHLVRREVMIWTGKLPKFEDESYNTKKDDLFLIPTAEVPITA
LHAEEILKEKELPKKYVSYTSCYRREAGSYGKDVRGMIRQHQFDKVELVWFTKEEESFNALEQLTRDAERILQLLELPYR
VVNLCTGDLGFASAKTYDIEVWLPSYNDYKEVSSCSNITDFQARRANIKYRGSDNKTHFVHTLNGSGLAIGRTLVAIMEN
YQNEDGTITIPKVLVPYMGVEKISI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-94 50