Gene Information

Name : Tmel_1269 (Tmel_1269)
Accession : YP_001306503.1
Strain : Thermosipho melanesiensis BI429
Genome accession: NC_009616
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 1276868 - 1278172 bp
Length : 1305 bp
Strand : -
Note : TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase

DNA sequence :
ATGGATAGACTGGAATTGTTAAAAAAAAGATTATCCGAGTACAATCCTTATCAAAAAATAGGGGCAGTCAGTAAAATAGT
GGGACTCACAATAGAATCAAAAGGTCCAGATGCCTTTTTGGGAGAACTTTGTAAGATAATCACAGAATACAAAAAGTCAT
ACGCAGAAGTAGTAGGGTTTAACGAAAATGGCGTTATATTAATGCCATTAGAAGATATTTCTGGTTTAAAAAAAGGGTGT
CAAGTAATAAAAACCAACCAATATGTAAGTATACCTGTATCCGAAGAACTCTTGGGTAGGGTAGTTGATGCTCTCGGAAG
GCCTCTAGATGGTAAGAAAATTCTTTCTAAAGAAAAAATTCCAATAGTTCGAGAAGCACCAAATCCGCTCATTAGAAAAA
GAATAACGACGCCTATTTCAGTTGGAATAAGGGCAATTGATGGTTTTCTAACTCTTGGATACGGTCAAAGAATTGGTATT
TTTGCTGGTAGTGGTGTGGGAAAAAGTACGCTACTTGGTATGATAGCTAGAAATACTTCTGCCGATATAAACGTAATTTC
TCTAATTGGTGAAAGAGGAAGAGAAGTTAGGGAATTTATAGAAAAAGACTTAAAAAAAGAAGGATTAAAACGTTCAATTG
TCGTTGTTTCTACATCCGACCAACCTGCCTTACTTAGAGTAAAAGCACTTTTAACAGCAACATCGATAGCAGAATATTTC
AGAGATAAGGGATACAACGTGTTGTTGATGGTAGATTCTTTAACCAGATGGGCTATGGCACAAAGGGAAGTGGGACTTGC
AACCGGTGAACCGCCAACAACAAGAGGTTATCCACCAAGTGTTTTTGCTGGATTACCAAAAATATTAGAAAGAGCTGGAA
ATTCTGACAAAGGAAGTATAACAGGTATTTACACTGTTCTTGTAGAAGCCGATGACTTTAATGAGCCTATTTCAGATACG
GTTAGAGGAATAGTAGACGGTCATATAATCCTTTCGAGAAAACTTGCAGAATCAGCACATTATCCTGCAATTGACGTATT
AATGAGTGTGAGTAGATTAATGAACGACATTGTAACAAAAGAACATAAAATTTCCGCTATGAAACTTAAAGACTTAATAG
CAACATATTACGATGCAAAGGATTTAATCGATGTTGGTGCATATAAAAAAGGAACAAATCCAAAAATAGATAAATCCATT
GAATTAATTGATGAAATAAATAAATTTCTAAAACAATCAATAGATGAAAGCATGAGTTTTGATGATACAGTACAATACTT
AATTTCAATAGCCAAAAAAATATAG

Protein sequence :
MDRLELLKKRLSEYNPYQKIGAVSKIVGLTIESKGPDAFLGELCKIITEYKKSYAEVVGFNENGVILMPLEDISGLKKGC
QVIKTNQYVSIPVSEELLGRVVDALGRPLDGKKILSKEKIPIVREAPNPLIRKRITTPISVGIRAIDGFLTLGYGQRIGI
FAGSGVGKSTLLGMIARNTSADINVISLIGERGREVREFIEKDLKKEGLKRSIVVVSTSDQPALLRVKALLTATSIAEYF
RDKGYNVLLMVDSLTRWAMAQREVGLATGEPPTTRGYPPSVFAGLPKILERAGNSDKGSITGIYTVLVEADDFNEPISDT
VRGIVDGHIILSRKLAESAHYPAIDVLMSVSRLMNDIVTKEHKISAMKLKDLIATYYDAKDLIDVGAYKKGTNPKIDKSI
ELIDEINKFLKQSIDESMSFDDTVQYLISIAKKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-83 52
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-83 52
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-97 50
escN AAK26715.1 EscN Virulence LEE Protein 2e-87 50
escN AAL57542.1 EscN Virulence LEE Protein 2e-87 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-87 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-87 50
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-86 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-97 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-97 49
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-96 49
escN AAC31513.1 L0034 Virulence LEE Protein 6e-87 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-87 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-87 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-87 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 8e-87 49
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-87 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 8e-87 49
escN AAC38383.1 EscN Virulence LEE Protein 7e-87 49
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-96 49
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-96 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-96 49
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-96 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-93 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-93 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-85 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-85 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-86 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-86 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-86 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 8e-87 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-86 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-80 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-80 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-80 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-78 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 8e-81 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-74 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-86 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-72 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-80 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-80 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-76 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-76 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG2144 Protein 1e-97 52
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG0390 Protein 7e-97 51
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG1254 Protein 6e-94 50
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG0192 Protein 5e-100 49
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG0048 Protein 1e-97 49
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG0812 Protein 3e-87 49
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG0730 Protein 4e-87 49
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG0515 Protein 3e-86 48
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG2331 Protein 5e-86 47
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG2499 Protein 1e-84 46
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG2459 Protein 2e-76 42
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG1778 Protein 7e-69 42
Tmel_1269 YP_001306503.1 flagellar protein export ATPase FliI VFG1008 Protein 2e-68 41