Gene Information

Name : Tmel_1067 (Tmel_1067)
Accession : YP_001306312.1
Strain : Thermosipho melanesiensis BI429
Genome accession: NC_009616
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 1093621 - 1094796 bp
Length : 1176 bp
Strand : +
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like

DNA sequence : 
ATGCATAAAATATCAGTAGCAGGAGCAGGATATGTGGGATTATCAATAGCAACAATGCTTTCTCAAAATCATAATGTAAC
TATACTTGACGTAGTAGATAAAAAGGTTAAAATGATAAATGAACGAATATGTCCGATTAAGGACAAAGAGATAGAAGAAT
TTTTTAAAACAAAAAAATTAAATTTGAAAGCAACGCTTGATAAATATGAAGCATATAAAAATTCAGAATATGTTATAGTA
GCAACTCCAACAAATTATGATCCTGAAAAAAATTACTTTGATACTTCCTCAGTTGAACAAGTAATACAAGATGTTTTAGA
AATAAATTCAAATGCTATTATCATAATAAAATCAACAATTCCAGTTGGTTTTACTAAAGAAATGAGAAAAAAATACAAAA
CTGATAATATTATATTTTCCCCTGAATTTTTAAGGGAAGGGAAAGCATTATATGATAATTTATATCCTTCAAGGATTGTA
GTGGGGGAAAAGTCTGAGAGGGCAAAAAGATTTGCCGATTTGCTACTTGAAGGTGCGATAAAAAAAGATGTTCCAATACT
TCTTACTGATTCAACAGAAGCTGAAGCAATTAAGTTATTTGCAAACACCTATCTTGCAATGAGAGTAGCGTTTTTTAACG
AACTTGATACTTATTGTGAGATTAAGGGGCTTAATACAAGACAGGTTATTGAAGGTGTTTGTCTTGATCCAAGAATAGGA
ATGTATTATAATAATCCTTCTTTTGGATATGGAGGTTATTGTTTGCCAAAAGATACAAAACAACTTTTAGCAAATTATGA
AAAAGATAAAGTTCCACAAAAACTTATTAAAGCTATTGTGGAATCAAATCAAGTTAGAAAACAGCATATTGCATATATGA
TAGAAAGAAGAAAGCCAAAAGTGATAGGTGTATATAGATTAATAATGAAAAAGGATTCAGATAATTTTAGACAATCAGCA
ATATTAGATGTGATGGATATTTTAAAAGAAAAAGGTTATGAGATAATAATATATGAACCTGTTATAAAAGAGAAAGAATT
TGAAGGGATTAAAGTTGAAAAGAATTTAGAAAAGTTTAAAAAAATTTCAGATGTAATACTTGCCAATAGGATGTTTAAAG
ATTTGGAAGATGTGGAAGGGAAAGTTTATACAAGAGATTTGTTTAATAGGGATTGA

Protein sequence : 
MHKISVAGAGYVGLSIATMLSQNHNVTILDVVDKKVKMINERICPIKDKEIEEFFKTKKLNLKATLDKYEAYKNSEYVIV
ATPTNYDPEKNYFDTSSVEQVIQDVLEINSNAIIIIKSTIPVGFTKEMRKKYKTDNIIFSPEFLREGKALYDNLYPSRIV
VGEKSERAKRFADLLLEGAIKKDVPILLTDSTEAEAIKLFANTYLAMRVAFFNELDTYCEIKGLNTRQVIEGVCLDPRIG
MYYNNPSFGYGGYCLPKDTKQLLANYEKDKVPQKLIKAIVESNQVRKQHIAYMIERRKPKVIGVYRLIMKKDSDNFRQSA
ILDVMDILKEKGYEIIIYEPVIKEKEFEGIKVEKNLEKFKKISDVILANRMFKDLEDVEGKVYTRDLFNRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 4e-92 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmel_1067 YP_001306312.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 1e-101 59