Gene Information

Name : BDI_0522 (BDI_0522)
Accession : YP_001301920.1
Strain : Parabacteroides distasonis ATCC 8503
Genome accession: NC_009615
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 617438 - 618193 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGATGAAGTTTATAGGAATTATTCCGGCGAGATACGCCTCTACCCGTTTTCCGGGGAAGCCATTAGCGGATATGAACGG
AAAGCCCATGATACAACGTGTATATGAGCAAGTAAAGGATGTCTTAGACTCCGTTTGCGTAGCTACCGACGATATCCGGA
TAGAGAATGCGGTTAAAGCCTTCGGCGGCCAAGTCGTCATGACCTCCGATCAACATCGTAGCGGTACGGATCGTTGCTAC
GAGGCTTATCAGAAAATAGGCGAAGGGTATGATGTGATTGTCAATATCCAAGGTGACGAGCCTTTTATCCATCCCGAGCA
AATCCAGACGATCAAAACCTGCTTCGCCGACGCAAACACGCAAATAGCGACATTGGTAAAGCCTTTCCGTTCGGACGATG
ATTTCGAGAGTTCCCTATTCAATCCCAATTCCCCGAAAGTCGTACTCAACAAAAACAACGAGGCTATGTATTTCAGTCGA
TCTATTATTCCTTATATCCGGGGCAAGAAATATACGGAATGGTTGCCGAGTCATACCTTTTACAAACATATCGGGTTATA
TGCCTATCGTGCGCAAGTGCTGAAAGAAATCACCCAATTACCTCAATCCGCTTTAGAACTGGCGGAAAGCCTTGAGCAAT
TACGCTGGTTGGAAAACGGATATAAAATCAAGGTCGGCATCACAGAGCAAGAAACGATCGGTATAGATACACCGGAGGAC
ATGGAGAAAGCCTTAGCCTTCCTTGCGAACCGCTGA

Protein sequence : 
MMKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSVCVATDDIRIENAVKAFGGQVVMTSDQHRSGTDRCY
EAYQKIGEGYDVIVNIQGDEPFIHPEQIQTIKTCFADANTQIATLVKPFRSDDDFESSLFNPNSPKVVLNKNNEAMYFSR
SIIPYIRGKKYTEWLPSHTFYKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPED
MEKALAFLANR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-35 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-35 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 8e-36 44