Gene Information

Name : guaA (BDI_1829)
Accession : YP_001303190.1
Strain : Parabacteroides distasonis ATCC 8503
Genome accession: NC_009615
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2180318 - 2181838 bp
Length : 1521 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACGAGAAACTTATTATTCTTGATTTCGGCTCGCAGACAACCCAGCTTATCGGCCGTAGGGTCAGAGAGTTGAATAT
GTATTGTGAGATCGTTCCTTATAACAAATTCCCGCATGACGCTACCGACGTGAAAGGTGTGATCCTTTCCGGAAGTCCTT
ATTCCGTATACGACGAGAATGCCTTTAAGGCTGATTTGACCGAGATACGGGGGAAGTATCCCGTCTTAGGTATTTGTTAT
GGAGCGCAGTTTCTAGCTTATACATCCGGAGGTAATGTGGAACCGGCTAATTCACGTGAGTATGGACGTGCTAATTTGTC
GCACATTGATGGTGAGGATGAATTACTGAAAGGGATCCATGTGGGTTCACAGATATGGATGTCTCATGGGGATACGATTA
CCGTATTGCCGGATAATTTCAAGGTGATCGCCAGCACGGACGACGTGAGGGCTGCCGCTTACCATGTGGAAGGTGAGCAA
ACGTGGGGCGTTCAGTTTCATCCGGAAGTATTCCATTCGACAGACGGTACGAAGTTGCTGGATAACTTCTTGAATATTTG
CGGATGCGCCAAGGATTGGACACCGGCTTCCTTTATCGAATCTACCGTAGCTGAGTTGAAGGAGCAATTGGGAGATGACA
AGGTGATCTTGGCTCTTTCCGGCGGTGTGGATTCATCTGTTACGGCCGTATTGCTGAATAAGGCGATCGGTAAGAACTTG
ACTTGCATTTTCGTGGATCATGGTTTGCTGCGCAAGAATGAGTTCGAGAACGTAATGAGGGATTATGAGCATTTAGGATT
GAACGTGATCGGCGTAAACGCAAAAGATAAGTTCTATAAAGAACTAGCGGGCGTTACGGAACCGGAGAAGAAACGTAAGA
TCATCGGCAAAGGATTTATCGATGTCTTCGATGAGGAGGCGCATAAGCTGAAAGATATCAAGTGGCTGGGGCAAGGTACG
ATTTATCCGGATGTGATCGAGTCGCTTTCTATCACAGGTACGGTTATCAAGAGCCATCATAATGTGGGCGGACTTCCGGA
TACGATGAACTTGAAACTCGTCGAGCCGCTTCGTCTTCTTTTCAAGGATGAGGTTCGCCGTGTCGGTATGGAGTTGGGTA
TGCAACCGCATTTGATCAAGCGCCATCCGTTCCCGGGACCGGGATTGGGTATCCGTATCTTGGGTGATATCACGCCGGAA
AAGGTACGTATCCTGCAAGACGCTGACGATATCTATATGTCATTGATGCGTGAGTGGGGACTTTACGATAAGATTTGGCA
AGCTGGGGTAATCTTACTTCCGATTCAATCCGTAGGTGTAATGGGCGATGAGCGTACCTATGAGAATACGGTAGCTTTAC
GTGCGGTCACTTCCACGGACGCTATGACCGCCGATTGGGCGCAGCTTCCGTACGAGTTCCTCGCCAAAGTTTCCAACGAG
ATTATCAATAAGGTGAAAGGCGTGAATAGAGTCGTGTACGACATCAGCTCGAAGCCGCCTGCAACCATCGAGTGGGAGTG
A

Protein sequence :
MHEKLIILDFGSQTTQLIGRRVRELNMYCEIVPYNKFPHDATDVKGVILSGSPYSVYDENAFKADLTEIRGKYPVLGICY
GAQFLAYTSGGNVEPANSREYGRANLSHIDGEDELLKGIHVGSQIWMSHGDTITVLPDNFKVIASTDDVRAAAYHVEGEQ
TWGVQFHPEVFHSTDGTKLLDNFLNICGCAKDWTPASFIESTVAELKEQLGDDKVILALSGGVDSSVTAVLLNKAIGKNL
TCIFVDHGLLRKNEFENVMRDYEHLGLNVIGVNAKDKFYKELAGVTEPEKKRKIIGKGFIDVFDEEAHKLKDIKWLGQGT
IYPDVIESLSITGTVIKSHHNVGGLPDTMNLKLVEPLRLLFKDEVRRVGMELGMQPHLIKRHPFPGPGLGIRILGDITPE
KVRILQDADDIYMSLMREWGLYDKIWQAGVILLPIQSVGVMGDERTYENTVALRAVTSTDAMTADWAQLPYEFLAKVSNE
IINKVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-122 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-122 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-122 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-112 47