Gene Information

Name : guaA (BVU_3587)
Accession : YP_001300822.1
Strain : Bacteroides vulgatus ATCC 8482
Genome accession: NC_009614
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4449723 - 4451276 bp
Length : 1554 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAAGAAAAGATCATTATTCTCGACTTCGGTTCACAAACCACACAGCTCATAGCCCGTCGCGTTCGCGAACTGAATAC
TTATTGCGAGATTGTGCCTTACAACAAATTTCCACACAATGATCCGTCCATAATCGGCGTTATCCTTTCGGGAAGCCCTT
TCTCGGTGTATGATGAAAGCGCCTTTAAAGTCGATTTGAGTGACATTCGCGGAAAGTATCCTATTTTGGGTATCTGCTAT
GGTGCACAGTTCATGTCTTATACAAACGGTGGGAAAGTGGAACCGGCCGGCACACGTGAATACGGACGTGCACACCTTTC
CACTTTCGACCAAGAGAACCCACTATTGAAGAACGTCCGTGAACACTCACAAGTATGGATGAGCCACGGAGATACCATCA
CCGCCATTCCGGAGAATTTCAAAATTATCGCTTCAACAGATAAAGTAGCCATCGCTGCTTATCAAATAAAGGAAGAGAAA
GTATGGGGAGTACAGTTCCACCCGGAAGTGTTCCACAGTGAAGACGGAACCCAGCTTCTGAAAAATTTTGTAGTCGACAT
TTGCGGGGGGAAACAGGACTGGAGCGCTGCCTCTTTCATTGAAACGACTGTAGCCGAACTGAAAGCGCAACTGGGAAATG
ACAAAGTAGTACTGGGGCTGAGTGGCGGAGTAGACTCATCTGTGGCAGCCGTATTATTAAATAAAGCGATAGGCAAGAAT
CTTACCTGCATTTTTGTAGATCACGGCATGCTGCGTAAGAACGAATTCAAAAATGTACTCCATGATTATGAATGTCTCGG
ACTGAATGTAATCGGAGTGGATGCCAGCCAAAAATTCTTCAGTGAACTGGCAGGTGTGGAAGAACCTGAGAAGAAGCGTA
AGATTATCGGTAAAGGTTTTATTGACGTATTCGATGAAGAAGCTCATAAAATTAAAGATGTGAAATGGCTGGCACAAGGT
ACCATTTATCCTGACTGTATCGAGTCATTAAGTATCACCGGCACTGTAATCAAAAGTCATCACAACGTAGGTGGACTGCC
CGAAAAAATGAATTTGAAACTATGCGAGCCTCTGCGTCTGCTATTCAAGGATGAAGTACGCCACGTAGGTCGTGAACTGG
GTATGCCGGAACATCTGATTACACGCCATCCATTCCCCGGACCAGGACTTGCGGTACGTATTTTGGGTGATATCACTCCT
GAGAAAGTACGTATTCTGCAAGACGCCGATGATATCTATATCCAAGGATTGAGAGACTGGAAAGTGAAAGACTCGGACGG
AAACGAAACATCCCTTTACCACCAAGTATGGCAGGCAGGCGTAATCTTGCTACCCGTACAAAGTGTGGGAGTAATGGGGG
ACGAACGTACATACGAACGTGCCGTTGCCCTACGTGCCGTAACTAGTACGGATGCCATGACCGCCGACTGGGCTCATCTT
CCCTATGAATTTATGGCTAAGGTTTCAAACGACATAATCAATAAAGTAAAAGGTGTAAACCGCGTATGCTATGATATCTC
GTCCAAACCGCCTGCCACAATTGAGTGGGAATAA

Protein sequence :
MQEKIIILDFGSQTTQLIARRVRELNTYCEIVPYNKFPHNDPSIIGVILSGSPFSVYDESAFKVDLSDIRGKYPILGICY
GAQFMSYTNGGKVEPAGTREYGRAHLSTFDQENPLLKNVREHSQVWMSHGDTITAIPENFKIIASTDKVAIAAYQIKEEK
VWGVQFHPEVFHSEDGTQLLKNFVVDICGGKQDWSAASFIETTVAELKAQLGNDKVVLGLSGGVDSSVAAVLLNKAIGKN
LTCIFVDHGMLRKNEFKNVLHDYECLGLNVIGVDASQKFFSELAGVEEPEKKRKIIGKGFIDVFDEEAHKIKDVKWLAQG
TIYPDCIESLSITGTVIKSHHNVGGLPEKMNLKLCEPLRLLFKDEVRHVGRELGMPEHLITRHPFPGPGLAVRILGDITP
EKVRILQDADDIYIQGLRDWKVKDSDGNETSLYHQVWQAGVILLPVQSVGVMGDERTYERAVALRAVTSTDAMTADWAHL
PYEFMAKVSNDIINKVKGVNRVCYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-118 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-118 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-118 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-111 46