Gene Information

Name : CGSHiGG_03125 (CGSHiGG_03125)
Accession : YP_001292008.1
Strain : Haemophilus influenzae PittGG
Genome accession: NC_009567
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 573421 - 574710 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCAAATTTACTCCGTAATAATTTAGCAGAAGTCGCAGAAAAATTAAAAGTAAAACGCAACTTTATGCTTGA
TACGGAAAAACTCACTGCGTTAGAAGATCAGCGCAAAAACTTACAAGTCACTACCGAAAACTTACAAGCGGAACGTAATG
CTCGTTCCAAAGCCATTGGTGCTGCTAAAGCACGTGGTGAAGATATCGCACCATTATTGGCAGAAATGGATGATATGGGC
AATCAATTGACTGAAGCAAAAGCACAATTAGATGCGGTACTTGCAGAAATCAATCAAATTGCACTAAGTATTCCAAATCT
ACCCGCGGACGAAGTGCCATTAGGCAAAGATGACACAGAAAATAAAGAAATCTTACGTTGGGGAACACCGCGTACATTTG
ATTTTGAAGTCAAAGATCATGTCACTTTGGGTGAAGAAGCAAATGGCTTAGATTTTGCTGCTGGGGCTAAATTAACTGGT
GCGCGTTTTGCCGTAATGAAAGGTCAAATCGCTAAAATGCACCGCGCATTGGCACAATTCATGTTAGATCTTCATACGGA
ACAACACGGCTATTTAGAAACCTATGTGCCTTATTTAGTAAATCACGCCACACTTTATGGAACAGGGCAATTACCAAAAT
TCGGGGAAGATTTATTCCATACTTTAGCCTTACAAGGCGAACAACCTTACGCATTAATTCCAACCGCAGAAGTGCCAGTC
ACTAATTTAGTGCGTGATGTAATTATTGATGAAGCAGAATTACCAATAAAAATGACCGCACATACGCCATGTTTCCGTTC
TGAAGCAGGCTCTTACGGTCGTGATACTCGTGGTTTAATTCGTATGCACCAATTTGATAAAGTAGAAATGGTACAAATCG
TTGATCCAGATAAATCAATGGAAGCACTTGAAGAATTAACAGGTCATGCGGAAAAAGTATTGCAATTATTAAATTTACCA
TACCGTAAAGTTTTACTTTGCACAGGCGATATGGGCTTTGGTTCTTGCAAGACTTACGATTTAGAAGTCTGGGTGCCTGC
ACAAAATACTTATCGTGAAATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCTCGCCGTATGCAAGCACGTTGTAAAG
CAAAAGGGGATAAGAAAACCCACTTAGTGCATACCTTAAATGGTTCTGGCTTGGCTGTTGGTCGTACTTTAGTGGCTGTG
CTTGAAAACTATCAAAATGCCGATGGTTCAATCACCGTGCCAGAAGTGCTACGTCCATATATGGGCGGATTAGACGTTAT
CGGAAAATAA

Protein sequence :
MIDPNLLRNNLAEVAEKLKVKRNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAIGAAKARGEDIAPLLAEMDDMG
NQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDTENKEILRWGTPRTFDFEVKDHVTLGEEANGLDFAAGAKLTG
ARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLFHTLALQGEQPYALIPTAEVPV
TNLVRDVIIDEAELPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLP
YRKVLLCTGDMGFGSCKTYDLEVWVPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTHLVHTLNGSGLAVGRTLVAV
LENYQNADGSITVPEVLRPYMGGLDVIGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-104 53