Gene Information

Name : CGSHiGG_02800 (CGSHiGG_02800)
Accession : YP_001291965.1
Strain : Haemophilus influenzae PittGG
Genome accession: NC_009567
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 513645 - 514409 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGTCATTTACCGTGATTATCCCTGCTCGTTTTGCATCAAGTCGTTTGCCTGGAAAACCGCTTGCTGATATTGCAGGTAA
GCCAATGATTCAACATGTATTTGAGAAAGCACTGCAGTCTGGGGCGAACCGAGTGATTATTGCCACCGATAATGAAAATG
TGGCTGATGTTGTCAAAAATTTTGGCGCAGAAGTGTGCATGACTTCGGTTAATCATAATTCTGGTACAGAACGTTTAGCG
GAAGTTGTAGAAAAATTAGCGATTCCTGACAATGAAATCATTGTCAATATTCAAGGCGATGAGCCTTTGATTCCTCCCGT
TATCGTGCGACAAGTGGCAGATAATTTAGCAAAATTTAATGTAAATATGGCAAGCCTTGCGGTAAAAATTCACGATGGCG
AGGAATTATTTAATCCAAATGCAGTGAAAGTTTTGACGGATAAAGACGGCTATGTGCTATATTTTTCCCGTTCGGTTATT
CCTTACGATCGTGATCAGTTTATGAATTTACAGGATGTTCAGAAAGTACAGCTTGCGGACGCTTACTTACGTCATATTGG
CATTTACGCATATCGTTCGGGGTTCATAAAACAATATATGCAATGGGCTCCGACTCAACTTGAAAATCTAGAAAAACTTG
AGCAGCTTCGTGTGTTATATAACGGCGAACGCATTCATGTGGAGCTTGCGAAAGAAGTGCCTGCAGTGGGGGTGGATACT
GCTGAAGATTTGGAAAAAGTGCGGCTGATTTTGGCGAAGGATTAA

Protein sequence : 
MSFTVIIPARFASSRLPGKPLADIAGKPMIQHVFEKALQSGANRVIIATDNENVADVVKNFGAEVCMTSVNHNSGTERLA
EVVEKLAIPDNEIIVNIQGDEPLIPPVIVRQVADNLAKFNVNMASLAVKIHDGEELFNPNAVKVLTDKDGYVLYFSRSVI
PYDRDQFMNLQDVQKVQLADAYLRHIGIYAYRSGFIKQYMQWAPTQLENLEKLEQLRVLYNGERIHVELAKEVPAVGVDT
AEDLEKVRLILAKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-40 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-39 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-40 43