Gene Information

Name : murD (CGSHiGG_09340)
Accession : YP_001293049.1
Strain : Haemophilus influenzae PittGG
Genome accession: NC_009567
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 1732486 - 1733799 bp
Length : 1314 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAATGCCTATCAAAACAAAAATATTACGATCATTGGGCTTGGCAAAACAGGTCTTTCTTGTGTGGATTATCTCTTATC
CCAACAGGCTAATATTCGTGTGATTGATACTCGAAAAAATCCTACTGGTATTGATAAACTTCCTCAAAATATCCCTCTTC
ATACTGGTAGTTTAAATCAGGAATGGTTACTTGAAAGCGATATGATTGTTATCAGTCCAGGGCTTGCGGTAAAAACACCT
GAAATTCAAACCGCACTTAAAGCCGGCGTAGAAGTAATCGGTGATATTGAATTATTTTGCCGCGCAGCGACAAAGCCAAT
TGTGGGGATTACAGGTTCAAATGGTAAAAGTACCGTAACTACTTTAGTTTATGAAATGGCGAAAGCTGCTGGCGTGAAAG
TTGGTATGGGCGGAAATATTGGGATTCCCGCTTTGTCATTGTTGAATGAAGATTGTGAACTTTATGTACTAGAGCTTTCT
AGTTTTCAGCTTGAGACGACTTATAGCTTAAAAGCTGCGGCTGTGACTGTTTTGAACGTGACTGAAGATCATATGGATCG
CTATATGGATTTAGAAGATTATCGCCAAGCAAAATTACGTATTCATCATAATGCTAAAGTAGGTGTGTTGAACAATGAAG
ATAGGCTGACTTTTGGGGAAAACGAAAATCAAGCGAAACATACCGTTTCTTTTGCGGAAAATAGTGCGGATTATTGGCTA
AAAACTGAAAATGGCAAGCAATATTTAATGGTAAAAGATGAAGTGATTTTACCTTGTGAAGAAGCTACATTGGTTGGTCG
CCATAATTATATGAACATTTTGGCAGCAACAGCATTGGCACAAGCTATAGGTATTAATTTAGATTCAATTCGTACCGCAC
TTCGTCATTTCAAAGGGTTAGATCATCGTTTTCAATTAGTGCATCAAGCTAATGGCATTCGTTGGATTAATGACTCTAAA
GCAACAAATGTGGGGAGTACAGTTGCTGCATTGGCTGGGCTTTATATTGAGGGTAAATTGCATTTGTTGCTAGGTGGAGA
CGGAAAAGGGGCTGATTTTTCAGAATTAGCTGAATTAATTAATCAACCACACATTATTTGTTATTGTTTTGGTCGAGATG
GTGCGCAGCTTGCAAAATTTTCATCGCAAAGCTATTTGTTTGAAACAATGGAACAAGCGATAGAATTTTTACGCCCAACA
TTGCAAAGCGGAGATATGGTATTATTGTCGCCTGCTTGTGCAAGTCTCGATCAGTTTGCTTCTTTTGAAAAGCGCGGCGA
AGAATTTACGCATTTAGCTCAATATTCAGTCTAA

Protein sequence :
MNAYQNKNITIIGLGKTGLSCVDYLLSQQANIRVIDTRKNPTGIDKLPQNIPLHTGSLNQEWLLESDMIVISPGLAVKTP
EIQTALKAGVEVIGDIELFCRAATKPIVGITGSNGKSTVTTLVYEMAKAAGVKVGMGGNIGIPALSLLNEDCELYVLELS
SFQLETTYSLKAAAVTVLNVTEDHMDRYMDLEDYRQAKLRIHHNAKVGVLNNEDRLTFGENENQAKHTVSFAENSADYWL
KTENGKQYLMVKDEVILPCEEATLVGRHNYMNILAATALAQAIGINLDSIRTALRHFKGLDHRFQLVHQANGIRWINDSK
ATNVGSTVAALAGLYIEGKLHLLLGGDGKGADFSELAELINQPHIICYCFGRDGAQLAKFSSQSYLFETMEQAIEFLRPT
LQSGDMVLLSPACASLDQFASFEKRGEEFTHLAQYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 1e-53 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 1e-53 41