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Name : leuS (CGSHiGG_08170) Accession : YP_001292851.1 Strain : Haemophilus influenzae PittGG Genome accession: NC_009567 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1508337 - 1510922 bp Length : 2586 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAACAATATCGCCCCGATATGATCGAACCAAAGGTTCAACAATATTGGGTAGAAAATAAAGTTTTCAAAGCAAT CAAAGACGAATCTAAAGAAAAATATTACTGTCTTTCTATGTTCCCATATCCTTCTGGTCGCCTACATATGGGGCACGTGC GTAACTACACTATTGGTGATGTAATTTCTCGTTATCAACGCATGCTAGGTAAAAACGTATTGCAACCATTTGGTTGGGAT GCTTTCGGCTTACCAGCAGAAGGTGCCGCAATCAAAAACAAAACTGCGCCTGCTAAATGGACGTACGAAAACATTGCCTA CATGAAAAAACAACTTCAGCTTTTAGGCTTTGGTTTCGACTGGGATCGCGAAATCGCAACCTGTAAACCAGAATACTACA AATGGGAACAATGGTTCTTCACGGAGCTTTATAAAAAAGGCTTAGTGTACAAAAAAACCTCAACCGTAAACTGGTGCCCG AATGATGAAACAGTACTCGCAAACGAGCAAGTACATGAAGGTTGTTGCTGGCGTTGTGATACACCAGTGGAACAAAAAGA AATTCCACAATGGTTTATCAAAATTACTGACTATGCCGAGCAATTATTAGGTGGTTTAGATACCCTTCCTCAATGGCCTG ATATGGTAAAAACCATGCAACGTAACTGGATTGGTCGTTCTGAAGGGGTAGAAATTACCTTTGATGTTGCAAATACCAAC GAAAAAGTGGCGGTTTACACCACGCGTCCAGATACCTTTTACGGTGTGAGTTATTTAGGTATTGCGGCGGCACATCCATT AGCAAGTTTGGCAGCTCAAAATAATCCCGAATTAGCCGCCTTTATCCAAGAAGCGAAAAACGCCAAAGTGGCAGAAGCTG ATCTTGCGACAATGGAGAAAAAAGGAATGGCAACGGGCTTATTTGCTATTCATCCATTGACGGGCGAAAAATTACCGATT TGGGTCGCTAATTTCGTGTTAATGCACTACGGTACTGGCGCAGTAATGGCAGTTCCTGCTCACGACCAACGTGACTTTGA ATTTGCTCAAAAATACAGTTTGCCAATTAAACAAGTGATCGCACCGCTTGCAGATGAAGAAATTGATTTAACTAAACAAG CTTTCGTTGAGCACGGTAAATTAGTGAACTCAGCTGAATTTGATGGTAAAGACTTTGATGGCGCATTCAACGGTATCGCG GATAAATTAGAAAAATTAGGTGTTGGAAAACGTCAAGTTAATTACCGTTTACGTGACTGGGGCGTTTCTCGCCAACGTTA TTGGGGTGCACCAATTCCGATGCTAACCCTTGAAAATGGCGATGTAGTACCTGCACCAATGGAAGATTTACCTATTATTC TACCTGAAGATGTGGTAATGGATGGCGTGAAAAGCCCAATTAAAGCTGATCCTAACTGGGCAAAAACAACCCTTAACGGC ACACCAGCGTTAAAAGAAACGGATACCTTTGATACCTTTATGGAATCCTCTTGGTATTACGCGCGCTACACTTGTCCACA ATATCAAAATGGCATGCTTGATGCGGAAGAAGCAAACTATTGGTTACCTGTGGATCAATATATCGGTGGTATTGAACACG CAACAATGCACTTGCTCTACTTCCGCTTCTTCCACAAATTGTTACGCGATGCAGGATTTGTAACCAGTGAGGAACCAGCC GATAAATTATTATGTCAAGGTATGGTGCTTGCAGATGCCTTCTACTACACAAGTCCAACCAATGAGCGTATTTGGGTGAG TCCAACACAGGTGACCCTTGAACGTGATGAAAAAGGCAGAATTATTAAAGCCACCGATCCTGAAGGGCGTGAATTAGTCC ACAGTGGCATGACCAAAATGTCGAAATCCAAAAATAACGGTATTGACCCACAGGAAATGGTAGAAAAATATGGTGCCGAT ACTGTTCGCCTCTTTATGATGTTTGCCTCTCCAGCAGAAATGACCTTGGAATGGCAAGAATCTGGCGTAGAAGGGGCGAA ACGTTTCTTAGGGCGTGTTTGGAATTTGGTATATCAATATCAACAAAATCCAGCAAAAACTAGCCTAGATATCACCGCAC TTTCCGCAGAACAAAAAGTGCTTCGTCGTGAAGTTCATAAAACCATTGCGAAAGTGAGCGATGATATTGGTCGTCGTCAA ACATTTAATACTGCGATTGCTGCAGTGATGGAATTGATGAATAAACTGACTAAGGCACCGCTTGATAGCGAGCAAGATCG TGCAGTTATGGCGGAGGCATTAAGTGCAGTTGTTCGTATGCTTTATCCAATTACTCCACATATCTGTTTTGAATTATGGC AAGCTCTTGGCAATGAAAGTGCTATTGATACTGCAGAATGGGTAAAAGCCGATGAAGCCGCAATGGTAGAAGATGAAAAA CTGATTGTTGTGCAAGTAAATGGCAAGGTTCGTGGCAAAGTTACTGTTGCGGCAGATGCAGATGAAGACACAGTCAAAAC GATTGCTTTTGCGGATGAAAATGTGAAGAAATTTATTGATAATCAACACATTGTCAAAGTGATTTATGTCGTAGGTAAAT TATTAAACGTGGTAGTGAAACCATAA Protein sequence : MQEQYRPDMIEPKVQQYWVENKVFKAIKDESKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPFGWD AFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTN EKVAVYTTRPDTFYGVSYLGIAAAHPLASLAAQNNPELAAFIQEAKNAKVAEADLATMEKKGMATGLFAIHPLTGEKLPI WVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQVIAPLADEEIDLTKQAFVEHGKLVNSAEFDGKDFDGAFNGIA DKLEKLGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILPEDVVMDGVKSPIKADPNWAKTTLNG TPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSEEPA DKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDDIGRRQ TFNTAIAAVMELMNKLTKAPLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQALGNESAIDTAEWVKADEAAMVEDEK LIVVQVNGKVRGKVTVAADADEDTVKTIAFADENVKKFIDNQHIVKVIYVVGKLLNVVVKP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 7e-152 | 41 |
