Gene Information

Name : CGSHiEE_03010 (CGSHiEE_03010)
Accession : YP_001290415.1
Strain : Haemophilus influenzae PittEE
Genome accession: NC_009566
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 606909 - 607673 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGTCATTTACCGTTATTATCCCCGCTCGTTTTGCATCAAGTCGTTTACCTGGAAAACCGCTTGCCGATATTGCAGGTAA
GCCAATGATTCAACATGTATTTGAGAAAGCACTGCAGTCTGGGGCGAGCCGAGTGATTATTGCCACCGATAATGAAAATG
TGGCTGATGTTGCCAAAAATTTTGGCGCGGAAGTGTGCATGACTTCGGTTAATCATAATTCTGGTACAGAACGTTTAGCG
GAAGTTGTAGAAAAATTAGCGATTCCTGACAATGAAATCATTGTCAATATTCAAGGCGATGAGCCTTTGATTCCTCCCGT
TATCGTGCGACAAGTGGCAGATAATTTAGCAAAATTTAATGTCAATATGGCAAGCCTTGCGGTAAAAATTCATGATGCTG
AGGAATTATTTAATCCAAATGCAGTGAAAGTATTAACAGATAAAGACGGCTATGTGCTGTATTTTTCCCGTTCGGTTATT
CCTTACGATCGTGATCAGTTTATGAATTTACAGAATGTTCAGAAAGTACAGCTTGCGGACGCTTACTTACGTCATATTGG
CATTTACGCATATCGTGCTGGTTTCATAAAACAATATGTGCAATGGGCACCGACTCAACTTGAAAATCTAGAAAAACTTG
AGCAGCTTCGCGTGTTATATAACGGCGAACGCATTCATGTTGAACTTGCGAAAGAGGTGCCTGCAGTGGGGGTAGATACC
GCTGAAGATTTGGAAAAAGTGCGGCTGATTTTGGCGAAGGATTAA

Protein sequence : 
MSFTVIIPARFASSRLPGKPLADIAGKPMIQHVFEKALQSGASRVIIATDNENVADVAKNFGAEVCMTSVNHNSGTERLA
EVVEKLAIPDNEIIVNIQGDEPLIPPVIVRQVADNLAKFNVNMASLAVKIHDAEELFNPNAVKVLTDKDGYVLYFSRSVI
PYDRDQFMNLQNVQKVQLADAYLRHIGIYAYRAGFIKQYVQWAPTQLENLEKLEQLRVLYNGERIHVELAKEVPAVGVDT
AEDLEKVRLILAKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-39 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-39 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-40 43