Gene Information

Name : CGSHiEE_02725 (CGSHiEE_02725)
Accession : YP_001290366.1
Strain : Haemophilus influenzae PittEE
Genome accession: NC_009566
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 542973 - 544262 bp
Length : 1290 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCAAATTTACTCCGTAATAATTTAGCAGAAGTCGCAGAAAAATTAAAAGTAAAACGCAACTTTATGCTTGA
TACGGAAAAACTCACCGCGTTAGAAGATCAGCGCAAAAACTTACAAGTCACTACCGAAAACTTACAAGCGGAACGTAATG
CTCGTTCCAAAGCCATTGGTGCTGCTAAAGCACGTGGTGAAGATATCGCACCATTATTGGCAGAAATGGATGATATGGGC
AATCAATTGACTGAAGCAAAAGCACAATTAGATGCGGTACTTGCAGAAATCAATCAAATTGCATTAAGTATTCCAAATCT
ACCCGCAGACGAAGTGCCATTAGGCAAAGATGACACAGAAAATAAAGAAATCTTACGTTGGGGTACACCGCGTACATTTG
ATTTTGAAGTCAAAGATCATATCACTTTGGGTGAAGAAGCAAATGGCTTAGATTTTGCTGCTGGGGCTAAATTAGCTGGT
GCGCGTTTCGCCGTAATGAAAGGTCAAATCGCTAAAATGCACCGTGCATTGGCACAATTCATGTTAGATCTTCATACGGA
ACAACACGGCTATTTAGAAACCTATGTGCCTTATTTAGTAAATCACGCCACACTTTATGGAACAGGGCAATTACCAAAAT
TCGGGGAAGATTTATTCCATACTTTAGCCTTACAAGGCGAACAACCTTACGCATTAATTCCAACCGCAGAAGTGCCCGTC
ACTAATTTAGTGCGTGACGTGATTATTGATGAAGCAAAATTACCAATAAAAATGACCGCACATACGCCATGTTTCCGTTC
TGAAGCAGGCTCTTACGGTCGTGATACTCGTGGTTTAATTCGTATGCACCAATTTGATAAAGTAGAAATGGTACAAATCG
TTGATCCAGATAAATCAATGGAAGCACTTGAAGAATTAACAGGTCATGCGGAAAAAGTATTGCAATTATTAAATTTACCA
TACCGTAAAGTTTTACTTTGCACAGGCGATATGGGCTTTGGTTCTTGCAAAACTTACGATTTAGAAGTTTGGGTGCCTGC
ACAAAATACTTATCGAGAAATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCTCGCCGTATGCAAGCTCGCTGTAAAG
CAAAAGGCGATAAGAAAACTCGCTTAGTGCACACATTAAATGGTTCAGGCTTAGCGGTTGGTCGTACTTTAGTAGCTGTG
CTTGAAAACTATCAAAATGCCGATGGTTCAATCACCGTACCAGAAGTGCTACGTCCATATATGGGCGGATTAGACGTTAT
CGGCAAATAA

Protein sequence :
MIDPNLLRNNLAEVAEKLKVKRNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAIGAAKARGEDIAPLLAEMDDMG
NQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDTENKEILRWGTPRTFDFEVKDHITLGEEANGLDFAAGAKLAG
ARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLFHTLALQGEQPYALIPTAEVPV
TNLVRDVIIDEAKLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLP
YRKVLLCTGDMGFGSCKTYDLEVWVPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTRLVHTLNGSGLAVGRTLVAV
LENYQNADGSITVPEVLRPYMGGLDVIGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-97 53