Gene Information

Name : CGSHiEE_02565 (CGSHiEE_02565)
Accession : YP_001290341.1
Strain : Haemophilus influenzae PittEE
Genome accession: NC_009566
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 505251 - 506153 bp
Length : 903 bp
Strand : +
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGCGTTGTTTAGCACTAGATATTGGTGGGACAAAAATTGCTGCGGCGATTGTAAAAAATGGCGAAATTGAGCAACGTCA
GCAAATTCATACACCACGTGAAAATGTAGTGGAGGGAATGCACCAAGCGTTAGGCAAATTGCTTGCTGATTATGAAGGGC
AGTTTGATTATGTAGCGGTAGCATCTACGGGTATCATCAATAATGGTATTTTAAGTGCATTAAATCCGAAAAACTTAGGT
GGCTTGGCGGAATTTCCACTTAAAGCGAGTATTGCAAAACATACGGATAAACCGATTGGTTTATTAAATGATGCACAAGC
TGCGACTTATGCGGAATATCAATTGCAAAATTCTGAACAGGTATCAAATTTTGTTTTTATTACCGTTTCAACAGGAGTTG
GCGGAGGGATTGTGCTGAACCAAATTTTGCAGACAGGTTCTCGTGGTATTGCTGGGCATATTGGTCATACATTAGCTGAT
CCAAATGGTGCGATCTGTGGTTGTGGTCGTCGAGGTTGTGTCGAAGCGATTGCTTCAGGGCGAGCAATTGAAGCAGTTTC
TTCCCAATGGGAAGATCCGTGCGATCCAAAAGAAGTGTTTGAGCGTTTTAGAAAAAATGATGAAAAAGCGACCGCACTTG
TCGAACGTTCTGCGAAAGCCATTGCTAATTTAATTGCTGATTTAGTGATTAGTTTAGATATTCAAAAAATCGCGATTGGT
GGCAGTGTGGGATTAGCTGAGGGATATTTATCTTTGGTTGAAAAATATTTACAAGATTTTCCTTCGATATATTGTTGTGA
AATTGAAACCGCTAAATTTGGACAAGATGCAGGTTTAATTGGCGCAGCTTATTGGGTAAAAGATGTTTTACTGGATAAGC
CTGAAGGAACAATTTATGGCTAA

Protein sequence : 
MRCLALDIGGTKIAAAIVKNGEIEQRQQIHTPRENVVEGMHQALGKLLADYEGQFDYVAVASTGIINNGILSALNPKNLG
GLAEFPLKASIAKHTDKPIGLLNDAQAATYAEYQLQNSEQVSNFVFITVSTGVGGGIVLNQILQTGSRGIAGHIGHTLAD
PNGAICGCGRRGCVEAIASGRAIEAVSSQWEDPCDPKEVFERFRKNDEKATALVERSAKAIANLIADLVISLDIQKIAIG
GSVGLAEGYLSLVEKYLQDFPSIYCCEIETAKFGQDAGLIGAAYWVKDVLLDKPEGTIYG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 2e-38 49
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 6e-34 43
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 6e-34 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CGSHiEE_02565 YP_001290341.1 N-acetylmannosamine kinase VFG1115 Protein 3e-34 43